"Diflorasone diacetate" from_date:2012

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                            1
                            2016European Dermatology Forum
                            Trip Score
                            NarrativeNarrative based
                            EvidenceEvidence based
                            ?
                            application on the mothers’ skin, appreciable levels of betamethasone 17, 21-dipropionate were detected in the fetal blood of mice and rabbits.20 Animal studies have found topical corticosteroids are also teratogenic. Diflorasone diacetate cream caused cleft palate after applied to pregnant rats’ skin at a dose of 0.001 mg/kg/day, which was just one-third of the equivalent human topical dose. The treated rats had a higher rate of fetal death than untreated controls when the dose was increased to 0.5 mg/kg/day.21 After topical application of diflorasone diacetate 0.016 mg/kg/day to pregnant rabbits, depressed fetal growth, external anomalies (31.9%), cleft palate (22.2%), and visceral defects (45.5%) were found.22 To sum up, animal experiments demonstrated that topical application of topical
                            2
                            2018FP Notebook
                            , Hydrocortisone Cream, Hydrocortisone Topical, Halobetasol Propionate, Ultravate, Temovate, Diprolene, Diflorasone diacetate, Psorcon, Amcinonide, Cyclocort, Diprosone, Mometasone furoate, Elocon, Florone, Fluocinonide, Lidex, Maxiflor, Desoximetasone, Topicort, Halcinonide, Halog, Hydrocortisone valerate, Westcort, Kenalog, Flurandrenolide, Cordran, Betamethasone valerate, Valisone, Hydrocortisone butyrate , spray cream 3. Diflorasone diacetate (Psorcon) 0.05% ointment 4. Flucinonide (Lidex) 0.1% cream 5. Flurandrenolide 4 mcg/cm2 tape 6. Halobetasol Propionate (Ultravate) 0.05% cream and ointment VI. Preparations: Level 2 (Very High Potency) 1. Halcinonide (Halog) 0.1% cream 2. Amcinonide (Cyclocort) 0.1% ointment 3. Betamethasone Dipropionate augmented (Diprolene AF) 0.05% cream 4. Betamethasone
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                            3
                            , groups A [eg, hydrocortisone, hydrocortisone-21-butyrate] and D2 [eg, hydrocortisone-17-butyrate] may be much more frequently observed than allergy to those corticosteroid molecules that are halogenated and have a methyl group at C16 (ie, groups D1 [eg, betamethasone dipropionate, clobetasol propionate, diflorasone diacetate, fluticasone propionate, mometasone furoate] and C [eg, desoximetasone
                            4
                            2014eMedicine.com
                            , groups A [eg, hydrocortisone, hydrocortisone-21-butyrate] and D2 [eg, hydrocortisone-17-butyrate] may be much more frequently observed than allergy to those corticosteroid molecules that are halogenated and have a methyl group at C16 (ie, groups D1 [eg, betamethasone dipropionate, clobetasol propionate, diflorasone diacetate, fluticasone propionate, mometasone furoate] and C [eg, desoximetasone
                            5
                            [eg, hydrocortisone-17-butyrate] may be much more frequently observed than allergy to those corticosteroid molecules that are halogenated and have a methyl group at C16 (ie, groups D1 [eg, betamethasone dipropionate, clobetasol propionate, diflorasone diacetate, fluticasone propionate, mometasone furoate] and C [eg, desoximetasone, desoxymethasone]). [30] C16-methylated corticosteroids should
                            6
                            2014eMedicine.com
                            , groups A [eg, hydrocortisone, hydrocortisone-21-butyrate] and D2 [eg, hydrocortisone-17-butyrate] may be much more frequently observed than allergy to those corticosteroid molecules that are halogenated and have a methyl group at C16 (ie, groups D1 [eg, betamethasone dipropionate, clobetasol propionate, diflorasone diacetate, fluticasone propionate, mometasone furoate] and C [eg, desoximetasone
                            7
                            2014eMedicine.com
                            without C16-methyl substitution in the D-ring (ie, groups A [eg, hydrocortisone, hydrocortisone-21-butyrate] and D2 [eg, hydrocortisone-17-butyrate] may be much more frequently observed than allergy to those corticosteroid molecules that are halogenated and have a methyl group at C16 (ie, groups D1 [eg, betamethasone dipropionate, clobetasol propionate, diflorasone diacetate, fluticasone propionate
                            8
                            2014eMedicine.com
                            [eg, hydrocortisone-17-butyrate] may be much more frequently observed than allergy to those corticosteroid molecules that are halogenated and have a methyl group at C16 (ie, groups D1 [eg, betamethasone dipropionate, clobetasol propionate, diflorasone diacetate, fluticasone propionate, mometasone furoate] and C [eg, desoximetasone, desoxymethasone]). [30] C16-methylated corticosteroids should
                            9
                            2015FP Notebook
                            , Hydrocortisone Cream, Hydrocortisone Topical, Halobetasol Propionate, Ultravate, Temovate, Diprolene, Diflorasone diacetate, Psorcon, Amcinonide, Cyclocort, Diprosone, Mometasone furoate, Elocon, Florone, Fluocinonide, Lidex, Maxiflor, Desoximetasone, Topicort, Halcinonide, Halog, Hydrocortisone valerate, Westcort, Kenalog, Flurandrenolide, Cordran, Betamethasone valerate, Valisone, Hydrocortisone butyrate , spray cream 3. Diflorasone diacetate (Psorcon) 0.05% ointment 4. Flucinonide (Lidex) 0.1% cream 5. Flurandrenolide 4 mcg/cm2 tape 6. Halobetasol Propionate (Ultravate) 0.05% cream and ointment VI. Preparations: Level 2 (Very High Potency) 1. Halcinonide (Halog) 0.1% cream 2. Amcinonide (Cyclocort) 0.1% ointment 3. Betamethasone Dipropionate augmented (Diprolene AF) 0.05% cream 4. Betamethasone