"Angioedema"

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                            2025Institute for Quality and Efficiency in Healthcare (IQWiG)
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                            Lanadelumab (hereditary angioedema, 2 to < 12 years) ' Benefit assessment according to '35a Social Code Book V 1 Translation of Sections I 1 to I 6 of the dossier assessment Lanadelumab (hereditäres Angioödem, 2 bis 11 Jahre)– Nutzenbewertung gemäß § 35a SGB V. Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers . However, solely the German original text is absolutely authoritative and legally binding. Lanadelumab (hereditary angioedema, 2 to 11 years) Benefit assessment according to §35a SGB V1 EXTRACT Project: A23-135 Version: 1.0 Status: 6 Mar 2024 DOI: 10.60584/A23-135_en Extract of dossier assessment A23-135 Version 1.0 Lanadelumab ( hereditary angioedema, 2 to 11 years) 6 Mar 2024 Institute for Quality
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                            Pharmacologic Management of ACE-Inhibitor Angioedema Pharmacologic Management of ACE-Inhibitor Angioedema - Emergency MedicineSkip to contentSkip to searchSkip to footerWashU MedicineEmergency Medicine Open MenuBackCloseMenuSearch for:SearchClose Search * AboutAbout * Clinical Sites * Community Impact * Explore St. Louis * Giving * Contact Us * Our TeamOur Team * Leadership * Faculty * Residency , and has been taking lisinopril for hypertension for the past six months. You and your attending discuss treatment options for bradykinin-mediated (ACE inhibitor) angioedema, including steroids and antihistamines. You consider alternative treatments such as TXA and FFP but given the stability of your patient elect to hold off on these. When you check on the patient 30 minutes later, he has since
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                            Berotralstat for preventing recurrent attacks of hereditary angioedema Berotralstat for preventing recurrent attacks of hereditary angioedema Technology appraisal guidance Published: 20 October 2021 www.nice.org.uk/guidance/ta738 © NICE 2021. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Your responsibility Your responsibility impact of implementing NICE recommendations wherever possible. Berotralstat for preventing recurrent attacks of hereditary angioedema (TA738)© NICE 2021. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Page 2 of21Contents Contents 1 Recommendations
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                            2024NIHR Innovation Observatory
                            Berotralstat for preventing recurrent attacks of hereditary angioedema in children aged 2 to <12 years Berotralstat for preventing recurrent attacks of hereditary angioedema in children aged 2 to * Who we are * What we do * Our Networks * Engage * Events * News * Resources Get in touch * * A world leading Horizon Scanning Facility The NIHR Innovation Observatory is a world leading health and care Mission * Our Values * What we do * Emerging horizon * Transitional horizon * Imminent horizon * Our Networks * Our Stakeholders * Our Work with NICE * Health & Life Sciences Ecosystem * Engage * Industry * Public Involvement * Capacity Building * Events * News * Resources * Contact 31 October 2024 Berotralstat for preventing recurrent attacks of hereditary angioedema in children aged 2 to Berotralstat
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                            2024NIHR Innovation Observatory
                            Donidalorsen for the prophylactic treatment of hereditary angioedema Donidalorsen for the prophylactic treatment of hereditary angioedema - NIHR Innovation Observatory * Who we are * What we do * Our Networks * Engage * Events * News * Resources Get in touch * * A world leading Horizon Scanning Facility The NIHR Innovation Observatory is a world leading health and care innovation scanning centre treatment of patients with hereditary angioedema (HAE). HAE is a rare inherited disorder characterised by recurrent episodes of the accumulation of fluids outside of the blood vessels, blocking the normal flow of blood or lymphatic fluid and causing rapid swelling of tissues in the hands, feet, limbs, face, intestinal tract, or airway causing discomfort and pain (angioedema). Donidalorsen is in clinical
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                            2021All Wales Medicines Strategy Group
                            Conestat alfa (Ruconest) - hereditary angioedema (HAE) Home - All Wales Therapeutics and Toxicology CentreSkip to main contentOpens in new window * NHS Wales * NHS 111 Wales * Skip Navigation * Accessibility * Contact us * CymraegCymraeg * Welcome to All Wales Therapeutics and Toxicology Centre * All...SearchAll Wales Therapeutics and Toxicology CentreSearchCymraegCymraegMenu * Home * COVID
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                            2023CADTH - Reimbursement Review
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                            Berotralstat (Orladeyo) - Hereditary angioedema (HAE) Return to Article DetailsBerotralstat (Orladeyo)
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                            2023CADTH - Reimbursement Review
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                            Berotralstat (Orladeyo) - Hereditary angioedema (HAE) Return to Article DetailsBerotralstat (Orladeyo)
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                            2021Institute for Quality and Efficiency in Healthcare (IQWiG)
                            Review Analysis
                            Appears Promising
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                            Berotralstat (hereditary angioedema) - Benefit assessment according to §35a Social Code Book V 1 Translation of Sections 2.1 to 2.5 of the dossier assessment Berotralstat (hereditäres Angioödem) – Nutzenbewertung gemäß § 35a SGB V (Version 1.0; Status: 13 September 2021). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Extract IQWiG Reports – Commission No. A21-80 Berotralstat (hereditary angioedema) – Benefit assessment according to §35a Social Code Book V1 Extract of dossier assessment A21-80 Version 1.0 Berotralstat (hereditary angioedema) 13 September 2021 Institute
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                            2021Institute for Quality and Efficiency in Healthcare (IQWiG)
                            Review Analysis
                            Appears Promising
                            ?
                            Lanadelumab (hereditary angioedema) - Benefit assessment according to §35a Social Code Book V 1 Translation of Sections 2.1 to 2.5 of the dossier assessment Lanadelumab (hereditäres Angioödem) – Nutzenbewertung gemäß § 35a SGB V (Version 1.0; Status: 12 August 2021). Please note: This translation is provided as a service by IQWiG to English -language readers. However, solely the German original text is absolutely authoritative and legally binding. Extract IQWiG Reports – Commission No. A21-63 Lanadelumab (hereditary angioedema) – Benefit assessment according to §35a Social Code Book V1 Extract of dossier assessment A21-63 Version 1.0 Lanadelumab ( hereditary angioedema) 12 August 2021 Institute for Quality and Efficiency in Health Care
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                            2022Scottish Medicines Consortium
                            Berotralstat (Orladeyo) - hereditary angioedema (HAE) PROSPEROInternational prospective register of systematic reviews Print | PDFEffectiveness of multi-professional educational interventions to train Comprehensive Geriatric Assessment (CGA) - a Systematic ReviewSonja Lindner-Rabl, Regina Roller-Wirnsberger, Katrin Singler, Maria Cristina Polidori Nelles, Gerald Seinost, Carolin HerzogTo enable
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                            2020FDA - Drug Approval Package
                            Berotralstat (Orladeyo) - To treat patients with hereditary angioedema Drug Approval Package: ORLADAYO * Skip to main page content * Skip to search * Skip to topics menu * Skip to common linksHHS U.S. Department of Health and Human Services U.S. Food and Drug Administration * Follow FDA * En EspañolSearch FDASubmit search * Popular Content * Home * Food * Drugs * Medical Devices * Radiation
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                            2021California Technology Assessment Forum
                            Prophylaxis of Hereditary Angioedema with Takhzyro and C1 Inhibitors: Effectiveness and Value ©Institute for Clinical and Economic Review, 2021 Observational Real-World Evidence Update Prophylaxis of Hereditary Angioedema with Takhzyro and C1 Inhibitors: Effectiveness and Value August 24, 2021 ©Institute for Clinical and Economic Review, 2021 Page i HAE RWE Update - Report DATE OF PUBLICATION: August 24, 2021 How to cite this document: Bloudek L*, Jaksa A*, McKenna A, Carlson J, Chen Y, Patrick A, Campbell JD. Observational Real-World Evidence Update; Prophylaxis of Hereditary Angioedema with Takhzyro and C1 Inhibitors: Effectiveness and Value. August 24, 2021. https://icer.org/assessment/hereditary-angioedema-2018/#timeline *Co-lead authors Lisa Bloudek and Ashley Jaksa served
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                            Lanadelumab for preventing recurrent attacks of hereditary angioedema Lanadelumab for preventing recurrent attacks of hereditary angioedema Technology appraisal guidance Published: 16 October 2019 www.nice.org.uk/guidance/ta606 © NICE 2021. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Your responsibility Your responsibility impact of implementing NICE recommendations wherever possible. Lanadelumab for preventing recurrent attacks of hereditary angioedema (TA606)© NICE 2021. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Page 2 of24Contents Contents 1 Recommendations
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                            Perioperative treatment for recurrent idiopathic angioedema Cookie NoticeThis site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our cookies information for more details.OKskip to main contentToggle site navigationAllergist Resources Ask The Expert 2023 Perioperative Treatment For Recurrent Idiopathic AngioedemaPerioperative treatment for recurrent idiopathic angioedemaQuestion:12/13/2023Allergy service consulted for preoperative (knee total replacement) assessment on a 60-year-old black male known to us for recurrent idiopathic angioedema. The onset of the episode was years ago. Angioedema episodes typically occur once every one to two months, affecting the periorbital areas, lips, and the uvula less frequently—the swelling entirely
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                            Urticaria and angioedema persistent after progesterone discontinuation Urticaria & angioedema after progesterone discontinuation Cookie NoticeThis site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our cookies information for more details. OK skip to main content Toggle site navigation * Annual Meeting * Ask The Expert * Journals * Find Statement * Membership * Advocacy * News & Press * Service and Stewardship * Strategic Relationships * Organizational Support 1. Allergist Resources 2. Ask The Expert 3. 2024 4. Urticaria and angioedema persistent after progesterone discontinuation Urticaria and angioedema persistent after progesterone discontinuationQuestion:10/29/2024I have a 37-year-old female that had onset of urticarial lesions
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                            THE RELATIONSHIP BETWEEN SURGICAL PROCEDURES AND ANGIOEDEMA ATTACKS IN HEREDITARY ANGIOEDEMA. Surgical interventions can trigger angioedema attacks in hereditary angioedema (HAE). The aim of this study was to assess the incidence of perioperative angioedema and identify associated risk factors. This retrospective study included HAE patients diagnosed between 1999 and 2024 at a tertiary adult allergy clinic. Data on surgical procedures and perioperative angioedema were analyzed. Of 102 HAE patients, 28 were excluded due to incomplete data, leaving 74 patients (46 female, 62.2%). Fifty-three patients underwent 94 surgeries, with the most common being gynecological (27, 28.7%), abdominal (27, 28.7%), and otorhinolaryngological (16, 17.0%). Of 54 surgeries before HAE diagnosis, 23 (42.5%) were
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                            2024NEJM
                            CRISPR-Cas9 In Vivo Gene Editing of KLKB1 for Hereditary Angioedema. Hereditary angioedema is a rare genetic disease that leads to severe and unpredictable swelling attacks. NTLA-2002 is an in vivo gene-editing therapy based on clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein 9. NTLA-2002 targets the gene encoding kallikrein B1 (), with the goal of lifelong control of angioedema attacks after a single dose. In this phase 1 dose-escalation portion of a combined phase 1-2 trial of NTLA-2002 in adults with hereditary angioedema, we administered NTLA-2002 at a single dose of 25 mg, 50 mg, or 75 mg. The primary end points were the safety and side-effect profile of NTLA-2002 therapy. Secondary and exploratory end points included pharmacokinetics
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                            Angioedema after semaglutide Cookie NoticeThis site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our cookies information for more details.OKskip to main contentToggle site navigationAllergist Resources Ask The Expert 2023 Angioedema After SemaglutideAngioedema after semaglutideQuestion:7/19/2023Do you have any recommendations for testing and a graded challenge to semaglutide (ozempic) in a patient who developed facial angioedema (including peri orbital swelling) two hours after taking semgalutide and ~ 12 hours after taking romosozumab. Despite discontinuation of the semaglutide, she continued to have episodes of swelling and it was thought to be due to the romosozumab. Since discontinuation of the romosozumab she has not had any further
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                            Prophylaxis for angioedema of tongue with normal complement and tryptase studies Cookie NoticeThis site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our cookies information for more details.OKskip to main contentToggle site navigationAllergist Resources Ask The Expert 2023 Prophylaxis For Angioedema Of Tongue With Normal Complement And Tryptase StudiesProphylaxis for angioedema of tongue with normal complement and tryptase studiesQuestion:7/14/2023An 82-year-old female who presents with CKD4, HTN, CAD, T2DM, has recurrent tongue swelling. In 2021 the patient had swelling due to ACE-I and ARB's, and contrast media. In 2021 she also had swelling which was felt to be due to losartan but occurred after intubation for COVID. On 6/26/23 she