"Benign neonatal sleep myoclonus"

Benign Neonatal Sleep Myoclonus Benign Neonatal Sleep Myoclonus: Background, Pathophysiology, Epidemiology For YouNews & PerspectiveDrugs & DiseasesCME & EducationAcademyVideoDecision PointEdition:EnglishMedscapeEnglishDeutschEspañolFrançaisPortuguêsUKNewUnivadisLog In Sign Up It's Free!English EditionMedscape * English * Deutsch * Español * Français * Português * UKNewUnivadisXUnivadis from =aHR0cHM6Ly9lbWVkaWNpbmUubWVkc2NhcGUuY29tL2FydGljbGUvMTM1NTU2Ny1vdmVydmlldw==processing....Drugs & Diseases > Pediatrics: Cardiac Disease and Critical Care Medicine Benign Neonatal Sleep MyoclonusUpdated: Dec 17, 2019 * Author: Marc P DiFazio, MD; Chief Editor: Ted Rosenkrantz, MD more... * * Share * Email * Print * FeedbackClose * Facebook * Twitter * LinkedIn * WhatsAppSections Benign Neonatal Sleep Myoclonus * * Sections Benign Neonatal Sleep Myoclonus

of an encephalopathy • Can also be seen in hyperekplexia7,10 • Can be stopped by flexion of the forehead to the chest7 Benign neonatal sleep myoclonus • Benign condition in which the infant has myoclonic jerks during sleep • Involves one or more limbs–more commonly observed in arms7,10 • Limb movements in slow wave sleep often just after falling asleep or waking up • Can be quite dramatic–whole body may shake7

HospitalMontrealQCCanadaDisclosuresLC declares that he has no competing interests. * * Differentials * Severe myoclonic epilepsy of infancy (Dravet syndrome) * Benign familial infantile seizures * Benign neonatal sleep myoclonus More Differentials * Guidelines * Epilepsies in children, young people and adults * Evidence-based guideline update: medical treatment of infantile spasms More Guidelines * Patient

HospitalMontrealQCCanadaDisclosuresLC declares that he has no competing interests. * * Differentials * Severe myoclonic epilepsy of infancy (Dravet syndrome) * Benign familial infantile seizures * Benign neonatal sleep myoclonus More Differentials * Guidelines * Epilepsies in children, young people and adults * Evidence-based guideline update: medical treatment of infantile spasms More Guidelines * Patient

* Benign neonatal sleep myoclonus * Nonepileptic apnea * Opisthotonos (hyperextension, back arching, spasticity – either physiologic or pathologic in cases of meningitis, tetanus) * Normal movementNon-neonates: * Syncope * BRUE * Breath-holding spells * Migraine with aura (vomiting, motor deficits, altered LOC) * Sydenham’s chorea * Various sleep disorders – narcolepsy, cataplexy * Tics * Psychogenic

/L. Sampling times were not reported.[6]Effects in Breastfed InfantsTwo side effects possibly related to sertraline in breastmilk have been reported to the Australian Adverse Drug Reaction Advisory Committee. Benign neonatal sleep myoclonus occurred in one 4-month-old infant and agitation that spontaneously resolved was reported in another infant.[22,23]None of 26 infants with an average age

Withdrawal for infants of mothers on longterm medications of drugs (e.g. Methadone, SSRI) 7. Benign neonatal sleep Myoclonus 1. Myoclonic Jerks while sleeping (resolves when infants are awake) 2. Presents at 2-4 weeks of life, and resolves by age 6 months 8. Saccadic Intrusions 1. When infants are tracking with their eyes, their eyes may make corrective jumps 1. Small amplitude

Respiratory Alkalosis * Pediatric Respiratory Failure * Pediatric Status Epilepticus * Pulmonary Infarction * Shock in Pediatrics * Treatment of Sepsis and Septic Shock in ChildrenNeonatology * Anemia of Prematurity * Apnea of Prematurity * Benign Neonatal Sleep Myoclonus * Birth Trauma * Breast Milk Jaundice * Bronchopulmonary Dysplasia * Chorioamnionitis * Congenital Pneumonia * Counseling * Atrioventricular Node Reentry Supraventricular Tachycardia * Atrioventricular Septal Defect Surgery * Benign Neonatal Sleep Myoclonus * Bicuspid Aortic Valve * Birth Trauma * Breast Milk Jaundice * Bronchopulmonary Dysplasia * Chest Wall Deformities * Chorioamnionitis * Circulatory Arrest and Cardiopulmonary Bypass Hypothermia * Coarctation of the Aorta * Commotio Cordis * Congenital Lung Malformations

, NREM parasomnias, and rapid eye movement (REM)–related parasomnias. Relevant miscellaneous sleep disorders include the following: * * Benign neonatal sleep myoclonus * * Bruxism * * Congenital hypoventilation syndrome * * Enuresis * * Infant sleep apnea * * Nocturnal paroxysmal dystonia * * Periodic limb movements * * Rhythmic movement

, NREM parasomnias, and rapid eye movement (REM)–related parasomnias. Relevant miscellaneous sleep disorders include the following: * * Benign neonatal sleep myoclonus * * Bruxism * * Congenital hypoventilation syndrome * * Enuresis * * Infant sleep apnea * * Nocturnal paroxysmal dystonia * * Periodic limb movements * * Rhythmic movement

, NREM parasomnias, and rapid eye movement (REM)–related parasomnias. Relevant miscellaneous sleep disorders include the following: * * Benign neonatal sleep myoclonus * * Bruxism * * Congenital hypoventilation syndrome * * Enuresis * * Infant sleep apnea * * Nocturnal paroxysmal dystonia * * Periodic limb movements * * Rhythmic movement

, NREM parasomnias, and rapid eye movement (REM)–related parasomnias. Relevant miscellaneous sleep disorders include the following: * * Benign neonatal sleep myoclonus * * Bruxism * * Congenital hypoventilation syndrome * * Enuresis * * Infant sleep apnea * * Nocturnal paroxysmal dystonia * * Periodic limb movements * * Rhythmic movement

, NREM parasomnias, and rapid eye movement (REM)–related parasomnias. Relevant miscellaneous sleep disorders include the following: * * Benign neonatal sleep myoclonus * * Bruxism * * Congenital hypoventilation syndrome * * Enuresis * * Infant sleep apnea * * Nocturnal paroxysmal dystonia * * Periodic limb movements * * Rhythmic movement

, NREM parasomnias, and rapid eye movement (REM)–related parasomnias. Relevant miscellaneous sleep disorders include the following: * * Benign neonatal sleep myoclonus * * Bruxism * * Congenital hypoventilation syndrome * * Enuresis * * Infant sleep apnea * * Nocturnal paroxysmal dystonia * * Periodic limb movements * * Rhythmic movement

Withdrawal for infants of mothers on longterm medications of drugs (e.g. Methadone, SSRI) 7. Benign neonatal sleep Myoclonus 1. Myoclonic Jerks while sleeping (resolves when infants are awake) 2. Presents at 2-4 weeks of life, and resolves by age 6 months 8. Saccadic Intrusions 1. When infants are tracking with their eyes, their eyes may make corrective jumps 1. Small amplitude

. It is important to distinguish them from epileptic seizures to avoid over- and inappropriate treatment. Some are physiological in the normal infant, such as neonatal tremor, benign neonatal sleep myoclonus, and shuddering attacks, whereas others may herald alternative rare neurological diagnoses with differing prognoses such as hyperekplexia, paroxysmal extreme pain disorder and alternating hemiplegia

Benign Neonatal Sleep Myoclonus: A Review of the Literature. Neurologically normal term infants sometimes present with repetitive, rhythmic myoclonic jerks that occur during sleep. The condition, which is traditionally resolved by 3 months of age with no sequelae, is termed benign neonatal sleep myoclonus. The goal of this review was to synthesize the published literature on benign neonatal reports in which 164 term-born (96%) or near-term-born (4%) infants were described. Neonatal sleep myoclonus occurred in all sleep stages, disappeared after arousal, and was induced by rocking the infant or repetitive sound stimuli. Furthermore, in affected infants, jerks stopped or even worsened by holding the limbs or on medication with antiepileptic drugs. Finally, benign neonatal sleep myoclonus did

responsiveness caused by the use of drugs are listed in Table 1. Other conditions that may imitate more focal epileptic seizures are omitted. Benign neonatal sleep myoclonus, apnea and apparent life-threatening events in infants, cyanotic and pallid breath-holding spells, syncope, staring spells, psychogenic seizures, hyperventilation syndrome, and narcolepsy have been selected based on frequency