" or "desensitizing agent*" or "desensitizing drug*" or "desensitizing medication*" or Dexmedetomidine or difelikefalin or Dihydroergotamine or dimiracetam or dizatrifone or doxpicomine or drinidene or Dronabino or Duloxetine or ecopladib or edronocaine or efipladib or elismetrep or C-3 "embelate potassium" or enkephalin or epibatidine or equagesic or Ergotamine or ethoheptazine or fadolmidine or fasinumab
Doxpicomine in postoperative pain. In a single-dose study the analgesic activity of 400 mg doxpicomine was compared with 4 and 8 mg morphine administered intramuscularly. Our subjects wee 43 men with moderate or severe postsurgical pain on the first postoperative day. Results of a double-blind trial indicate the analgesic activity of 400 mg intramuscular doxpicomine to be within the range of 8 mg morphine. There was no statistical significance between the effects of 400 mg doxpicomine and 8 mg morphine with the exception of half-hour data where doxpicomine was more effective than morphine. Doxpicomine has a rapid onset of analgesic action, the duration of which is equivalent to that of 8 mg morphine.
Further efficacy evaluation of doxpicomine for postoperative pain. In this single-dose, double-blind study, the analgesic activity of 400 and 200 mg doxpicomine was compared with 100 and 50 mg meperidine and placebo when given intramuscularly in 102 subject patients experiencing severe postoperative pain. Results indicate that 400 mg doxicomine is similar to 100 mg meperidine in analgesic