steroids were significantly higher in 21OHD patients: 17OHP (67-fold; P < .01), 21-deoxycortisol (21dF; 35-fold; P < .01), 16α-hydroxyprogesterone (16OHP; 28-fold; P < .01), progesterone (2-fold; P < .01), and 11β-hydroxyprogesterone (11OHP; not detected in controls; P < .01). The same steroids were the highest in media from TART cells relative to the NA cells: 11OHP, 58- to 65-fold; 21dF, 30- to 41-fold
it is a more specific marker of the 21-hydroxylase deficiency than 17α-hydroxyprogesterone. Even so, 21-deoxycortisol measurement has not been commonly performed by laboratories until 2019, thus, as of 2020, experience is limited.[35][36] * 21-Deoxycorticosterone, also known as 11β-hydroxyprogesterone (11β-OHP), have been proposed as a marker in 1987.[37][38] A study in 2017 has shown that in subjects