. CE are obtained from natural sources and are a mixture of sodium estrone sulphate, sodium equilin sulfate, and concomitant components, sodium sulfate conjugates, 17α-dihydroequilin, 17α-estradiol, and 17β-dihydroequilin. CE is a well-established therapy for the treatment of oestrogen deficiency symptoms (EDS) in postmenopausal women, available in the US since , molecular formulae and relative molecular mass of Defined Components in conjugated oestrogens Description Chemical Name Molecular Formulae relative molecular mass Conjugated Oestrogens Primary Components Sodium Estrone Sulfate (NES) Sodium Equilin Sulfate (NEQS) Concomitant Components Sod ium 17 α-Dihydroequilin Sulfate Sodium 17β-Dihydroequilin Sulfate 17-oxoestra-1,3,5(10)-trien-3-yl sodium
time from the control lag time of 57 ± 2 min was 0.47 for 17β-dihydroequilenin, 17α-dihydroequilenin, Δ-estrone; 0.6 to 0.7 for Δ-17β-estradiol, equilenin, and quercetin; 0.9 for 17β-dihydroequilin and 17α-dihydroequilin; 1.3 for equilin, estrone, 17β-estradiol, 17α-estradiol; 1.4 for trolox; 1.9 for probucol; and 3.0 for t-resveratrol. The data from the in vivo study indicate that after long-term