"Alzheimer's disease" from_date:2012

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                            1
                            2023NIHR HTA programme
                            Review Analysis
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                            A pragmatic, multicentre, double-blind, placebo-controlled randomised trial to assess the safety, clinical and cost-effectiveness of mirtazapine and carbamazepine in people with Alzheimer's disease and agitated behaviours: the HTA-SYMBAD trial Text onlyJournals LibraryNHS NIHR - National Institute for Health and Care ResearchSelectEMEGHRHSDRHTAPGfARPHR AdvancedJournalsEfficacy and Mechanism informationVIEW AWARDA pragmatic, multicentre, double-blind, placebo-controlled randomised trial to assess the safety, clinical and cost-effectiveness of mirtazapine and carbamazepine in people with Alzheimer's disease and agitated behaviours: the HTA-SYMBAD trialSube Banerjee, Nicolas Farina, Catherine Henderson, Juliet High, Susan Stirling, Lee Shepstone, Julia Fountain, Clive Ballard, Peter Bentham, Alistair
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                            2024European Medicines Agency - EPARs
                            Lecanemab (Leqembi) - Alzheimer's disease Official address Domenico Scarlattilaan 6 ● 1083 HS Amsterdam ● The Netherlands An agency of the European Union Address for visits and deliveries Refer to www.ema.europa.eu/how-to-find-us Send us a question Go to www.ema.europa.eu/contact Telephone +31 (0)88 781 6000 © European Medicines Agency, 2024. Reproduction is authorised provided the source is acknowledged. 26 July 2024 EMA/337466/2024 EMEA/H/C/005966 Refusal of the marketing authorisation for Leqembi (lecanemab) The European Medicines Agency has recommended the refusal of the marketing authorisation for Leqembi, a medicine intended for the treatment of Alzheimer’s disease. The Agency issued its opinion on 25 July 2024. The company that applied for authorisation, Eisai GmbH, may ask for re
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                            2024FDA - Drug Approval Package
                            Donanemab azbt (Kisunla) - Alzheimer's disease Drug Approval Package: KISUNLA * Skip to main content * Skip to FDA Search * Skip to footer links An official website of the United States governmentHere's how you know The .gov means it's official.Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site. The site
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                            2023BMJ Best Practice
                            Alzheimer's disease Skip to main contentSkip to searchAbout usHelpSubscribeAccess through your institutionLog inBMJ Best PracticeSearchSearchSelect languageAlzheimer's disease MENULog in or subscribe to access all of BMJ Best PracticeLast reviewed:10 Jan 2023Last updated:08 Feb 2023IMPORTANT UPDATESSummaryAlzheimer's disease (AD) is a chronic, progressive neurodegenerative disorder
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                            2025CADTH - Health Technology Review
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                            Health System Readiness for Disease-Modifying Therapies for Alzheimer Disease View of Health System Readiness for Disease-Modifying Therapies for Alzheimer Disease | Canadian Journal of Health Technologies Return to Article DetailsHealth System Readiness for Disease-Modifying Therapies for Alzheimer Disease
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                            2025NIHR Innovation Observatory
                            Blarcamesine for managing early Alzheimer's disease in people aged 55 to 85 years 16 DECEMBER 2024 Blarcamesine for managing early Alzheimer’s disease in people aged 55 to 85 years Blarcamesine is in clinical development for the treatment of mild cognitive impairment or earlystage mild dementia due to Alzheimer’s disease. Alzheimer’s disease is the most common cause of dementia in the UK . Alzheimer’s disease is a progressive condition, which means the symptoms develop gradually over many years and eventually become more severe. It affects multiple brain functions. Dementia is the name for a group of symptoms associated with an ongoing decline of brain functioning. It can affect memory, thinking skills and other mental abilities. The exact cause of Alzheimer’s disease is not yet fully
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                            2025Scottish Medicines Consortium
                            Lecanemab (Leqembi) - Alzheimer's disease 1 Published 10 February 2025 1 SMC2700 lecanemab concentrate for solution for infusion (Leqembi®) Eisai 10 January 2025 The Scottish Medicines Consortium (SMC) has completed its assessment of the above product and advises NHS Boards and Area Drug and Therapeutic Committees (ADTCs) on its use in NHSScotland. The advice is summarised as follows: ADVICE : following a full submission lecanemab (Leqembi®) is not recommended for use within NHSScotland. Indication under review: for the treatment of mild cognitive impairment and mild dementia due to Alzheimer’s disease in adult patients that are apolipoprotein E ɛ 4 (ApoEɛ4) heterozygotes or non-carriers. In a randomised, double-blind, phase III study, lecanemab reduced the cognitive and functional decline
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                            2023FDA - Drug Approval Package
                            Lecanemab irmb (Leqembi) - Alzheimer's disease Skip to main contentSkip to FDA SearchSkip to footer links An official website of the United States government Here's how you know U.S. Food and Drug Administration  Search   MenuSearch FDASubmit search Home Drugs Drug Approvals and Databases Drugs@FDADrug Approval Package: LEQEMBIShareTweetLinkedinEmailPrintCompany: Eisai Inc.Application Number
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                            2021NIHR HTA programme
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                            Losartan to slow the progression of mild-to-moderate Alzheimer's disease through angiotensin targeting: the RADAR RCT Losartan to slow the progression of mild-to-moderate Alzheimer's disease through angiotensin targeting: the RADAR RCT * Text only * * Home * Journals * * Other NIHR research * * For authors * For reviewers * About * * Accessibility * Journals LibraryNHS NIHR - National report documents * Download report documents * * Disclosure of interest * * * Download report XML * * Citation Tools * Print * * * * Responses to this report (0) * Permissions information View ProjectLosartan administered over 12 months did not alter brain atrophy in Alzheimer's disease. {{author}}{{author}}{{($index
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                            2023Austrian Institute of Health Technology Assessment
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                            Biomarkers in Alzheimer's Disease ENGLISH | DEUTSCH ATOM RSS 1.0 RSS 2.0SIMPLE SEARCHADVANCED SEARCHHELPSERVICESLOGINBrowseTypeSubjectAuthor / EditorInstitutionYear AIHTA - Publications - Search - Biomarkers in Alzheimer's DiseaseEttinger, S. and Jeindl, R. and Erdös, J. (2023): Biomarkers in Alzheimer's Disease. Rapid Review Nr.: 004. PDF - Sie müssen einen PDF-Viewer auf Ihrem PC installiert
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                            2023California Technology Assessment Forum
                            Lecanemab for Early Alzheimer's Disease ©Institute for Clinical and Economic Review, 2023 Page 1 Lecanemab for Early Alzheimer’s Disease: Final Policy Recommendations April 17, 2023 ©Institute for Clinical and Economic Review, 2023 Page 2 Policy Recommendations Introduction The following policy recommendations reflect the main themes and points made during the Policy Roundtable discussion at the March 17, 2023 CTAF public meeting on the use of lecanemab for the treatment of early Alzheimer’s disease. At the meeting, ICER presented the findings of its revised report on these treatments and the CTAF voting council deliberated on key questions related to their comparative clinical effectiveness, potential other benefits and contextual considerations, and long-term value for money
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                            2021FDA - Drug Approval Package
                            Aducanumab (Aduhelm) - For treatment of Alzheimer’s disease Drug Approval Package: Aduhelm (aducanumab-avwa) * Skip to main page content * Skip to search * Skip to topics menu * Skip to common linksHHS U.S. Department of Health and Human Services U.S. Food and Drug Administration * Follow FDA * En EspañolSearch FDASubmit search * Popular Content * Home * Food * Drugs * Medical Devices
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                            2024Brazilian Clinical Guidelines
                            Guidelines for the use and interpretation of Alzheimer's disease biomarkers in clinical practice in Brazil: recommendations from the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology In recent years, the diagnostic accuracy of Alzheimer's disease has been enhanced by the development of different types of biomarkers that indicate the presence make this scenario even more challenging in healthcare. This article presents the recommendations from the Scientific Department of Cognitive Neurology and Aging of the Brazilian Academy of Neurology () regarding the rational use and interpretation of Alzheimer's disease biomarkers in clinical practice. The clinical diagnosis of cognitive-behavioral syndrome is recommended as the initial step
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                            2020NIHR HTA programme
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                            Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer's disease: the MADE Phase II, three-arm RCT Minocycline 200 mg or 400 mg versus placebo for mild Alzheimer's disease: the MADE Phase II, three-arm RCT * Text only * * Home * Journals * * Other NIHR research * * For authors * For reviewers * About * * Accessibility * Journals LibraryNHS NIHR - National Institute for Health documents * Download report documents * * Disclosure of interest * * * Download report XML * * Citation Tools * Print * * * * Responses to this report (0) * Permissions information View ProjectMinocycline did not delay the progress of cognitive or functional impairment in people with mild Alzheimer's disease over 2 years and minocycline 400 mg
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                            2022CADTH - Horizon Scan
                            An Overview of New and Emerging Technologies for Early Diagnosis of Alzheimer Disease Skip to main contentAboutCollaboration/OutreachPatient/CommunityCareersContactMy CADTHFRReportsResourcesProvide InputSubmit a RequestNews & EventsWhat Does The Evidence Say About...SearchBreadcrumbHome An Overview of New and Emerging Technologies for Early Diagnosis of Alzheimer DiseaseCopied to clipboardAn Overview of New and Emerging Technologies for Early Diagnosis of Alzheimer Disease( Last Updated : May 16, 2022)Project Status:CompletedProject Line:Horizon ScanProject Sub Line:Emerging Health TechnologiesProject Number:EH0103-000DetailsAlzheimer disease is a progressive neurologic condition that leads to the decline of cognitive functioning and eventual death. Proposed causes of Alzheimer disease
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                            2022CADTH - Health Technology Review
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                            Utilization of Cholinesterase Inhibitors for Alzheimer's Disease in Canada Skip to main contentAboutCollaboration/OutreachPatient/CommunityCareersContactMy CADTHFRReportsResourcesProvide InputSubmit a RequestNews & EventsWhat Does The Evidence Say About...SearchBreadcrumbHome Utilization of Cholinesterase Inhibitors for Alzheimer’s Disease in CanadaCopied to clipboardUtilization of Cholinesterase Inhibitors for Alzheimer’s Disease in Canada( Last Updated : June 13, 2022)Project Status:CompletedProject Line:Health Technology ReviewProject Sub Line:Technology ReviewProject Number:HC0027-000DetailsAlzheimer disease (AD) is a progressive neurodegenerative disorder and the leading cause of dementia worldwide. The cholinesterase inhibitors (ChEIs) donepezil, galantamine, and rivastigmine are first-line
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                            2022ACE Horizon Scanning
                            The PrecivityAD Test for the Prognosis of Alzheimer's Disease ACE BRIEF FOR NEW AND EMERGING HEALTH TECHNOLOGIES The PrecivityAD Test for the Prognosis of Alzheimer’s Disease Document Number: HSB-M 01/2022 Date: Jan 2022 This briefing presents independent research by the ACE. It reflects the evidence available at the time of writing based on a limited literature search. It does not involve critical appraisal and is not intended to be a definitive statement on the safety, efficacy or effectiveness of the health technology covered. The views expressed are those of the author and not necessarily those of the ACE, or the Ministry of Health. 2 Summary of Key Points • Alzheimer’s disease (AD) is a neurodegenerative disorder whose main pathogenesis is attributed to senile plaques
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                            2021Swiss Federal Office of Public Health HTA
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                            Medicines for Dementia due to Alzheimer's Disease and Parkinson's Disease Medicines for Dementia due to Alzheimer's Disease and Parkinson's Disease * Homepage * Main navigation * Content area * Sitemap * SearchThe Federal Administration in treecrumb format * The federal Council * The federal Council admin.ch * FCh: Federal Chancellery * FDFA: Federal Department of Foreign Affairs : Federal Office of Meteorology and Climatology * Swissmedic: Swiss Agency for Therapeutic Products * FOGE: Federal Office for Gender Equality * FOPH * FOPH: Federal Office of Public Health Medicines for Dementia due to Alzheimer's Disease and Parkinson's DiseaseLanguages * DE * FR * IT * ENService navigation * Contact * Media * Jobs * Easy-to-read
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                            2020FDA - Drug Approval Package
                            Flortaucipir F18 (Tauvid) - Diagnostic agent for patients with Alzheimer’s disease Drug Approval Package: TAUVID * Skip to main page content * Skip to search * Skip to topics menu * Skip to common linksHHS U.S. Department of Health and Human Services U.S. Food and Drug Administration * Follow FDA * En EspañolSearch FDASubmit search * Popular Content * Home * Food * Drugs * Medical Devices
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                            2020Medical Services Advisory Committee
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                            F-18 Flurodeoxyglucose Positron Emission Tomography (FDG PET) for the diagnosis of Alzheimer’s disease MSAC - 1195.1 - F-18 flurodeoxyglucose positron emission tomography (FDG PET) for the diagnosis of Alzheimer Disease Skip to content Skip to site navigation Skip to local navigation Search Search Department of Health and Aged Care Medical Services Advisory CommitteeSearch Search * MSAC * About / * MSAC Applications / * Application Page /1195.1 - F-18 flurodeoxyglucose positron emission tomography (FDG PET) for the diagnosis of Alzheimer Disease Page last updated: 15 February 2021Application DetailDescription of Medical ServiceIt is proposed that flurodeoxyglucose positron emission tomography (FDG PET) brain imaging be Medicare Benefits Schedule (MBS) listed to diagnose Alzheimer Disease