"Bradycardia" from_date:2012

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                            1
                            2024BMJ Best Practice
                            Bradycardia Bradycardia - Symptoms, diagnosis and treatment | BMJ Best PracticeSkip to main contentSkip to search * English (US)EnglishPortuguês中文 * Log in * Personal account * Access through your institution(Open Athens) * Subscribe * Access through your institution * Log in * English (US)EnglishPortuguês中文 HomeSearchSearchHome * About usOverviewWhat is BMJ Best Practice?Our historyKey * Management * Approach * Treatment algorithm * Emerging * Prevention * Patient discussions * Follow up * Monitoring * Complications * Prognosis * Resources * Guidelines * Images and videos * References * Patient information Log in or subscribe to access all of BMJ Best PracticeLast reviewed: 23 Aug 2024Last updated: 17 Sep 2024SummarySinus bradycardia is any heart rhythm slower than 50 bpm, even
                            2
                            2022Medical Services Advisory Committee
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                            Procedures for the insertion or removal of a leadless permanent pacemaker for the treatment of bradyarrhythmia 1 ; Public Summary Document Application No. 1672 – Procedures for the insertion or removal of a leadless permanent pacemaker for the treatment of bradyarrhythmia Applicant: Medtronic Australasia Pty Ltd Date of MSAC consideration: 28-29 July 2022 Context for decision: MSAC makes its advice in accordance with its Terms of Reference, visit the MSAC website 1. Purpose of application An application requesting Medicare Benefits Schedule (MBS) listing of percutaneous transcatheter insertion or removal of a leadless permanent pacemaker (LPM) for the treatment of bradyarrhythmia that requires single-chamber ventricular pacing was received from the medical device company Medtronic
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                            3
                            Agency's (MHRA) Expert Advisory Group recommendations on leadless cardiac pacemaker therapy. 1.7 NICE may review this procedure on publication of further evidence. 2 2 The condition, current treatments and The condition, current treatments and procedure procedure The condition The condition 2.1 Bradyarrhythmias are abnormal heart rhythms that can result in a slow heart rate (bradycardia), usually defined Current treatments 2.2 Bradyarrhythmias are managed with pacemakers, as described in NICE technology appraisal guidance on dual-chamber pacemakers for symptomatic bradycardia due to sick sinus syndrome and/or atrioventricular block and dual-chamber pacemakers for symptomatic bradycardia due to sick sinus syndrome without atrioventricular block. Dual-chamber pacing is recommended for symptomatic
                            4
                            2025Nature Genetics
                            The impact of common and rare genetic variants on bradyarrhythmia development. To broaden our understanding of bradyarrhythmias and conduction disease, we performed common variant genome-wide association analyses in up to 1.3 million individuals and rare variant burden testing in 460,000 individuals for sinus node dysfunction (SND), distal conduction disease (DCD) and pacemaker (PM) implantation LMNA for all bradyarrhythmia phenotypes, SMAD6 and SCN5A for DCD and TTN, MYBPC3 and SCN5A for PM. These results show that variation in multiple genetic pathways (for example, ion channel function, cardiac developmental programs, sarcomeric structure and cellular homeostasis) appear critical to the development of bradyarrhythmias.
                            5
                            2018BMJ Best Practice
                            Bradycardia Bradycardia - Symptoms, diagnosis and treatment | BMJ Best PracticeSkip to main contentSkip to search * About us * Help * Subscribe * Access through your institution * Log inBMJ Best Practice * Help * Getting started * FAQs * Contact us * Recent updates * Specialties * Calculators * Patient leaflets * Videos * Evidence * Drugs * Recent updates * Specialties * Prognosis * Resources * Guidelines * Images and videos * References * Patient leaflets Log in or subscribe to access all of BMJ Best PracticeLast reviewed: 13 Jun 2022Last updated: 18 Nov 2021SummarySinus bradycardia is any heart rhythm slower than 50 bpm, even if transient, owing to sinus node dysfunction and/or atrioventricular (AV
                            6
                            2024JAMA Internal Medicine
                            Unusual Tachycardia in a Patient With Chest Pain and Bradycardia. This case report describes a patient in their 50s who presented with squeezing chest pain for 4 hours and an initial electrocardiogram showing acute inferior wall and right ventricular infarction with third-degree atrioventricular block.
                            7
                            2024eLife
                            Chemo- and optogenetic activation of hypothalamic Foxb1-expressing neurons and their terminal endings in the rostral-dorsolateral PAG leads to tachypnea, bradycardia, and immobility. -expressing neurons occur in the dorsal premammillary nucleus (PMd) and further rostrally in the parvafox nucleus, a longitudinal cluster of neurons in the lateral hypothalamus of rodents. The descending projection , hM3Dq-mediated, global neuron excitation activates respiration. Time-resolved optogenetic gain-of-function manipulation of the terminal endings of neurons in the rostral third of the dlPAG leads to abrupt immobility and bradycardia. Chemogenetic activation of cell bodies and ChR2-mediated excitation of their axonal endings in the dlPAG led to a phenotypical presentation congruent with a 'freezing
                            8
                            Comparison of clinical outcomes between transthoracic echocardiography- and X-ray-guided left bundle branch pacing for bradycardia: A randomized controlled trial. Left bundle branch pacing (LBBP) is a physiological pacing modality. However, the long procedure and fluoroscopy time of LBBP is still a problem. This study aims to compare the clinical outcomes between transthoracic echocardiography
                            9
                            2024Heart & Lung
                            Effects of bradycardia, hypoxemia and early intubation on bronchopulmonary dysplasia in very preterm infants: An observational study. Bronchopulmonary dysplasia (BPD) is the most common pulmonary complication in preterm infants. The study aimed to explore the effects of bradycardia, hypoxemia, and early intubation on BPD in very preterm infants. This is a prospective observational cohort study of bradycardia, hypoxemia, and early intubation on BPD in very preterm infants. Model fit was visually assessed using receiver operating characteristic curve analysis. Bradycardia, hypoxemia, and early intubation significantly increased the odds of BPD among the preterm infants (N = 39) during NICU stay; the odds ratios for bradycardia, hypoxemia, and early intubation for BPD versus non-BPD were 1.058, 1.013
                            10
                            2024Obesity Surgery
                            The Prevalence of Bradycardia 12 Years After Roux-en-Y Gastric Bypass for Severe Obesity. The aim was to describe the frequency of bradycardia 12 years after Roux-en-Y gastric bypass (RYGB), relations to weight loss, patient characteristics, and the clinical impact. The BAROPS study is a prospective observational study of patients who had follow-up > 10 years after RYGB. Patients with heart rate in heart rate. The only predictor of HR ≤ 50 was the use of beta-blockers (p = 0.010). There were no difference in bradycardia-related symptoms. Six percent of patients had HR ≤ 50 bpm 12 years after RYGB, but there was no increased bradycardia-related symptoms in these patients. RYGB induced a significant reduction in HR, and heart rate and changes in heart rate 12 years after RYGB were related
                            11
                            2024Pediatric Cardiology
                            Atrial Arrhythmia and Bradycardia as a Presentation of Congenital Long QT Syndrome. We present a term newborn with atrial arrhythmia on the first day of life (DOL). An echocardiogram showed normal structure and normal function; laboratory testing showed normal electrolytes and thyroid function. After initiation of flecainide, the EKG on DOL 2 showed significant and increasing bradycardia with atrial arrhythmia and extremely prolonged QTc interval. Flecainide was stopped and esmolol started. After 6 h of treatment, atrial tachycardia was suppressed, and the rhythm converted to sinus. Genetic testing found variants of unknown significance in the ALPK3 gene and KCNQ1 gene, which has been associated with long QT syndrome (LQTs). LQTs in infants can present as bradycardia, 2:1 AV block
                            12
                            2024BMC Cardiovascular Disorders
                            Comparison between catheter ablation versus permanent pacemaker implantation as an initial treatment for tachycardia-bradycardia syndrome patients: a prospective, randomized trial. Clinical outcomes after catheter ablation (CA) or pacemaker (PM) implantation for the tachycardia-bradycardia syndrome (TBS) has not been evaluated adequately. We tried to compare the efficacy and safety outcomes
                            13
                            2024Journal of Pediatrics
                            Apnea, Intermittent Hypoxemia, and Bradycardia Events Predict Late-Onset Sepsis in Extremely Preterm Infants. To examine the association of cardiorespiratory events, including apnea, periodic breathing, intermittent hypoxemia (IH), and bradycardia, with late-onset sepsis for extremely preterm infants (<29 weeks' gestational age [GA]) on versus off invasive mechanical ventilation quantified apnea, periodic breathing, bradycardia, and IH. We analyzed the relationships between these daily measures and late-onset sepsis (positive blood culture >72 hours after birth and ≥5d antibiotics). For infants not on a ventilator, apnea, periodic breathing, and bradycardia increased before sepsis diagnosis. During times on a ventilator, increased sepsis risk was associated with longer events
                            14
                            2024Circulation
                            Long-Term Incidence of Bradycardia and Pacemaker Implantations Among Cross-Country Skiers: A Cohort Study. Bradycardia is more common among well-trained athletes than in the general population, but the association with pacemaker implantations is less known. We investigated associations of endurance training with incidence of bradycardia and pacemaker implantations, including sex differences and long-term outcome, in a cohort of endurance trained individuals. All Swedish skiers who completed >1 race in the cross-country skiing event Vasaloppet between 1989 and 2011 (n=209 108) and a sample of 532 290 nonskiers were followed until first event of bradycardia, pacemaker implantation, or death, depending on end point. The Swedish National Patient Register was used to obtain diagnoses. Cox
                            15
                            2024Pediatric Cardiology
                            Effect of Bedside Ultrasound-Guided Versus Fluoroscopy-Guided Transvenous Cardiac Temporary Pacing in Children with Bradyarrhythmia. To compare the efficacy and safety of bedside ultrasound-guided and fluoroscopy-guided transvenous cardiac temporary pacing in the treatment of bradyarrhythmia in children. Children treated by temporary intravenous cardiac pacing from January 2016 to June 2023
                            16
                            2024Heart & Lung
                            Exploration of COVID-19 associated bradycardia using heart rate variability analysis in a case-control study of ARDS patients. Bradycardia and dysautonomia observed during SARS-Cov2 infection suggests involvement of the autonomic nervous system (ANS). Limited data exists on ANS dysregulation and its association with outcomes in patients with acute respiratory distress syndrome (ARDS) related with C-ARDS. A positive correlation was found between the low-to high-frequency ratio (LF/HF) and length of intensive care unit stay (r = 0.576, p<.001). This study confirmed that C-ARDS was associated with marked bradycardia and severe ANS impairment, suggesting a sympathovagal imbalance with vagal overtone. Poor outcomes appeared to be more related to sympathetic rather than parasympathetic
                            17
                            2024Pediatric Cardiology
                            Response to "Effect of Bedside Ultrasound‑Guided Versus Fluoroscopy‑Guided Transvenous Cardiac Temporary Pacing in Children with Bradyarrhythmia". The article "Effect of Bedside Ultrasound‑Guided Versus Fluoroscopy‑Guided Transvenous Cardiac Temporary Pacing in Children with Bradyarrhythmia" offers valuable insights into comparative short-term pacing strategies for pediatric bradyarrhythmias . This letter commends the study for its relevance and potential to improve patient care but highlights several limitations. Notably, the study overlooks the impact of genetic factors on bradyarrhythmias and treatment outcomes, lacks detailed information on the influence of medications, and does not address the cost-effectiveness of the pacing techniques. Future research should address these aspects
                            18
                            2024BMC Oral Health
                            Transient bradycardia during local anaesthesia to the oral cavity under intravenous sedation and its associate factors: a prospective observational study. Local anaesthesia in dental procedures is generally safe, although the occurrence of transient bradycardia (TB) has occasionally been reported. TB is often associated with two reflexes, the trigeminal cardiac reflex (TCR) and the vasovagal
                            19
                            Early bolus epinephrine administration during pediatric cardiopulmonary resuscitation for bradycardia with poor perfusion: an ICU-resuscitation study. Half of pediatric in-hospital cardiopulmonary resuscitation (CPR) events have an initial rhythm of non-pulseless bradycardia with poor perfusion. Our study objectives were to leverage granular data from the ICU-RESUScitation (ICU-RESUS) trial to: (1) determine the association of early epinephrine administration with survival outcomes in children receiving CPR for bradycardia with poor perfusion; and (2) describe the incidence and time course of the development of pulselessness. Prespecified secondary analysis of ICU-RESUS, a multicenter cluster randomized trial of children (< 19 years) receiving CPR in 18 intensive care units in the United
                            20
                            2024Anesthesiology
                            Repeated, High-dose Fentanyl Administration in Rats Reveals Minimal Tolerance to Unconsciousness, Bradycardia, Muscle Rigidity and Respiratory Depression. Fentanyl is a synthetic opioid that is widely used in anesthesiology, but its illicit use is rapidly increasing. At high doses fentanyl induces unconsciousness and muscle rigidity, the mechanisms of which are poorly understood. Since animal