'Mama, Can You Die from a BrokenHeart?' Exploring the Pathogenesis of Takotsubo Cardiomyopathy “Mama, Can You Die from a BrokenHeart?” Exploring the Pathogenesis of Takotsubo Cardiomyopathy – Clinical Correlations Clinical Correlations * AboutAboutAwardsPeer Review * CategoriesBedside RoundsChiefs' Inquiry CornerCORE IM PodcastDiseases 2.0EthicsEvolution and MedicineGamechanger?Healthcare PolicyHotSpotsMystery QuizMyths and RealitiesPrimeCutsSpotlightSee All Categories * SystemsAllergy/ImmunologyCardiologyDermatologyEndocrineGeriatricsGIHeme/OncIDMusculoskeletalNeuroNutritionPain/PalliativePsychiatryPulmonary/Critical CareRadiologyRenalRheumatologyUrology * Subscribe Search “Mama, Can You Die from a BrokenHeart?” Exploring the Pathogenesis of Takotsubo CardiomyopathyOctober 9, 2024 Uncategorized 4
Brick Walls and BrokenHearts: Physicians Draw how they Feel About Treating Pain and Addiction. As part of a continuing medical education activity, primary care physicians in Arizona were asked to draw how they feel about treating patients with chronic pain and addiction. Their drawings, complete with cliffs, walls, torn-out hair, and connected hearts, make for a harrowing look at burnout, angst
Recovering from a brokenheart. A molecular signature found in the brains of monogamous prairie voles begins to decay after prolonged separation from their partner.
Rationale and design of BROKEN-SWEDEHEART: a registry-based, randomized, parallel, open-label multicenter trial to test pharmacological treatments for brokenheart (takotsubo) syndrome. Takotsubo syndrome (TS) is a life-threatening acute heart failure syndrome without any evidence-based treatment options. No treatment for TS has been examined in a randomized trial. BROKEN-SWEDEHEART
Tbx1 orchestrates an immune niche that safeguards a brokenheart. Cardiac lymphatics cooperate with the reparative immune response in myocardial healing after infarction. In this issue of Immunity, Wang and colleagues discover a mechanism underlying this cooperation, dependent on the transcription factor Tbx1 and responsible for the creation of an immunosuppressive niche that mitigates
Macrophage efferocytosis with VEGFC and lymphangiogenesis: rescuing the brokenheart. Cardiac repair following ischemic injury is indispensable for survival and requires a coordinated cellular response involving the mobilization of immune cells from the secondary lymphoid organs to the site of damage. Efferocytosis, the engulfment of cell debris and dying cells by innate immune cells, along
Lymphatics in the brokenheart. Cardiac lymphatics have emerged as a therapeutic target in cardiovascular diseases to limit myocardial edema and inflammation, notably after myocardial infarction (MI). While most experimental therapeutic approaches have focused on vascular endothelial growth factor C (VEGF-C) delivery, it remains uncertain to what degree the beneficial cardiac effects are related
Lymphatic vessels help mend brokenhearts. Experiments on zebrafish show that the regeneration of the heart after an injury is supported by lymphatic vessels.
Clinical impact of advanced chronic kidney disease on outcomes and in-hospital complications of Takotsubo Syndrome (broken-heart-syndrome): Propensity-matched national study. Multiple studies evaluated the outcomes and complications rate of Takotsubo Syndrome (TTS) in patients with and without advanced chronic kidney disease (CKD), revealed conflicting results. This study aims to assess
Mending a BrokenHeart: Treatment of Stress-Induced Heart Failure after Solid Organ Transplantation Stress-induced heart failure, also known as BrokenHeart Syndrome or Takotsubo Syndrome, is a phenomenon characterized as rare but well described in the literature, with increasing incidence. While more commonly associated with postmenopausal women with psychiatric disorders, this entity is found
Potential Role of Exosomes in Mending a BrokenHeart: Nanoshuttles Propelling Future Clinical Therapeutics Forward Stem cell transplantation therapy is a promising adjunct for regenerating damaged heart tissue; however, only modest improvements in cardiac function have been observed due to poor survival of transplanted cells in the ischemic heart. Therefore, there remains an unmet need
BrokenHeart Syndrome in a Patient on Maintenance Hemodialysis Brokenheart syndrome or Takotsubo cardiomyopathy (TC) is a disorder characterized by transient left ventricular apical ballooning that almost invariably precedes emotional or physical stress. Although the patients with chronic kidney disease on hemodialysis have shown to exhibit sustained activity of sympathetic nervous system
Tis the Season for….BrokenHearts? Tis the Season for....BrokenHearts? - Evidence-Based Nursing blog Skip to content * Home * Topic Index * JournalTis the Season for….BrokenHearts?Posted on December 17, 2018 by rhealeRoberta Heale Associate Editor @robertaheale, @EBNursingBMJFor many of us, our hearts fill with joy as the holiday season settles upon us. For many others, this time of year includes sadness or stresses so strong they can break a heart. I recently travelled to visit a friend who had suffered the loss of her husband and then soon afterward had been hospitalized for chest pain and shortness of breath. After numerous investigations, she was told that, thankfully, she didn’t have a heart attack. Rather, she was diagnosed with brokenheart syndrome.Broken heart syndrome, also
BrokenHeart Syndrome: A Systematic Review PROSPERO International prospective register of systematic reviews Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission is accurate and complete. CRD bears
No more brokenhearts: weight loss after bariatric surgery returns patients' postoperative risk to baseline following coronary surgery. The obesity epidemic is associated with a rise in coronary surgeries because obesity is a risk factor for coronary artery disease. Bariatric surgery is linked to improvement in cardiovascular co-morbidities and left ventricular function. No studies have
Brokenheart, tako-tsubo or stress cardiomyopathy? Metaphors, meanings and their medical impact. The cardiac impact of psychological stress historically and socially understood as boundary experiences of human life has long since become an icon. From the aching heart to the sudden death provoked by awe, horror, grief, anger, and humiliation on one side and extreme enchantment, enthusiasm , and excitement on the other, the brokenheart has become a globally recognized and powerful metaphor present from folklore to popular culture to high literature and back to everyday communication. In medicine, the "brokenheart syndrome" is described as a relatively new nosological entity that has been used synonymously with the term tako-tsubo or stress cardiomyopathy. Among those three terms, however