The prevalence of peanut-triggered foodprotein-inducedenterocolitissyndrome in a prospective cohort of infants introducing peanut in the first year of life. Since the early introduction of peanut to prevent IgE-mediated peanut allergy, other case series have suggested an increased incidence of peanut-triggered FoodProteinInducedEnterocolitisSyndrome (FPIES). Data on the prevalence
Wheat-Triggered FoodProtein-InducedEnterocolitisSyndrome in Celiac Children on Gluten-Free Diet: A New Clinical Association. The association between foodprotein-inducedenterocolitissyndrome (FPIES) and wheat ingestion in children with celiac disease is unknown at this time. We present seven cases of children with celiac disease who presented with symptoms of wheat-triggered acute FPIES
Discrepancy between Caregivers' Reports and Physicians' Evaluation of Causative Foods in FoodProtein-InducedEnterocolitisSyndrome in Japan: The Japan Environment and Children's Study. Foodprotein-inducedenterocolitissyndrome (FPIES) is a form of non-IgE-mediated gastrointestinal food allergy. FPIES is considered a rare food allergy disorder and is often under-recognized. Therefore
Whole Exome Sequencing Identifies Epithelial and Immune Dysfunction-Related Biomarkers in FoodProtein-InducedEnterocolitisSyndrome. Foodprotein-inducedenterocolitissyndrome (FPIES) is a food allergy primarily affecting infants, often leading to vomiting and shock. Due to its poorly understood pathophysiology and lack of specific biomarkers, diagnosis is frequently delayed. Understanding
Formulation of Adult Food-Protein-InducedEnterocolitisSyndrome Diagnostic Scoring System Differentiating from Immediate-type Food Allergy. Adult foodprotein-inducedenterocolitissyndrome (FPIES) has recently been recognized, and there are no international diagnostic criteria for this disease. Differentiating adult FPIES from immediate-type food allergy reactions and providing specific
Current status and future directions in FoodProtein-InducedEnterocolitisSyndrome (FPIES): An NIAID Workshop Report. Food Protein-Induced Enterocolitis (FPIES) is a non-IgE mediated GI food allergy characterized by delayed, protracted vomiting, accompanied by lethargy and pallor, usually 1-4 hours following ingestion of the food allergen. The pathophysiology of FPIES remains unknown
Comparison of Adult Food-Protein-InducedEnterocolitisSyndrome to Crustaceans and Immediate-Type Food Allergy. Food-protein-inducedenterocolitissyndrome (FPIES) is increasingly seen in adults. FPIES requires different treatment from immediate-type food allergy (FA) in emergency medicine. However, no comparison of the clinical presentations of these diseases has been reported. To compare
Early infancy dysbiosis in foodprotein-inducedenterocolitissyndrome: a prospective cohort study. The microbiome associations of foodprotein-inducedenterocolitissyndrome (FPIES) are understudied. We sought to prospectively define the clinical features of FPIES in a birth cohort, and investigate for the evidence of gut dysbiosis. We identified children diagnosed with FPIES
Pearls and pitfalls in foodprotein-inducedenterocolitissyndrome (FPIES). Foodprotein-inducedenterocolitissyndrome (FPIES) is a rare, non-immunoglobulin E (IgE) mediated gastrointestinal food hypersensitivity. It is a clinical diagnosis commonly characterized by profuse vomiting 1 to 4 hours after ingestion of the triggering food(s). The objective was to increase awareness of FPIES
Recent trends in foodprotein-inducedenterocolitissyndrome (FPIES). Foodprotein-inducedenterocolitissyndrome (FPIES) was first described in detail in the late 20th century as a non-IgE-mediated food allergy characterized by delayed gastrointestinal symptoms after ingestion of a trigger food. Although the initial case series reported infants reacting to cow's milk- and soy-based formulas, we
Differentiation of foodprotein-inducedenterocolitissyndrome misleading to necrotizing enterocolitis. Foodprotein-inducedenterocolitissyndrome (FPIES) is a rare non-immunoglobulin E-mediated food allergy with necrotizing enterocolitis (NEC)-like symptoms which requires differential diagnosis as treatments differ. To evaluate the clinical, laboratory, and radiologic findings
Foodprotein-inducedenterocolitissyndrome in the British Isles. Foodprotein-inducedenterocolitissyndrome (FPIES) is a delayed type of food allergy, most often seen in infancy. We aimed to estimate its incidence, to describe common food triggers and the patient journeys of this rare but serious condition. We undertook a prospective epidemiological survey of FPIES using the British Paediatric
Potential of Thymus and Activation-Regulated Chemokine (TARC) as a Prognostic Biomarker of FoodProtein-InducedEnterocolitisSyndrome (FPIES) Caused by Egg Yolk. Several recent studies have reported egg yolk-associated foodprotein-inducedenterocolitissyndrome (FPIES) in Japan. We previously reported the usefulness of post-emetic thymus and activation-regulated chemokine (TARC) levels
Evaluation of the Clinical Characteristics of Patients with FoodProtein-InducedEnterocolitisSyndrome: A Multicenter Study. Foodprotein-inducedenterocolitissyndrome (FPIES) is a rare non-IgE, cell-mediated food allergy disorder. We aimed to report the demographic characteristics, clinical features, and management of pediatric patients with FPIES. This retrospective study included all
Differences in Thymus and Activation-Regulated Chemokine and Squamous Cell Carcinoma Antigen 2 Levels in FoodProtein-InducedEnterocolitisSyndrome and Atopic Dermatitis. We previously reported that thymus and activation-regulated chemokine (TARC) levels measured after vomiting are useful predictors of a foodprotein-inducedenterocolitissyndrome (FPIES) diagnosis. However, interpreting TARC
IL-27 as a potential biomarker for distinguishing between necrotising enterocolitis and highly suspected early-onset foodprotein-inducedenterocolitissyndrome with abdominal gas signs. The initial clinical manifestations and abdominal imaging findings of neonates with necrotising enterocolitis (NEC) and foodprotein-inducedenterocolitissyndrome (FPIES) are sometimes similar; however
Food aversion and poor weight gain in foodprotein-inducedenterocolitissyndrome: A retrospective study. Foodprotein-inducedenterocolitissyndrome (FPIES) is a form of non-IgE-mediated gastrointestinal food allergy. Insufficient data exist in regard to gastrointestinal history and outcome, particularly comorbidity, family history, food aversion, and poor body weight gain. We sought
Evaluation of the Diagnostic Accuracy of Thymus and Activation-Regulated Chemokine to Discriminate FoodProtein-InducedEnterocolitisSyndrome from Infectious Gastroenteritis. Post-emetic elevation in thymus and activation-regulated chemokine (TARC) levels has been reported in patients with foodprotein-inducedenterocolitissyndrome (FPIES); however, no studies have investigated differences
Foodprotein-inducedenterocolitissyndrome. Foodprotein-inducedenterocolitissyndrome (FPIES) is a non-IgE-mediated gastrointestinal food allergic disorder that has gained a major interest the past decade. FPIES prevalence, which still needs to be accurately determine in different populations, appears to be higher than previously thought (ie up to 0.7% in infants in the 1st year of life