COVID-19: High Flow Nasal Cannula (HFNC)/Non-Invasive PositivePressureVentilation (NIPPV) Indications COVID-19: HIGH FLOW NASAL CANNULA (HFNC) / NON-INVASIVE POSITIVEPRESSUREVENTILATION (NIPPV) INDICATIONS A Rapid Guidance Summary from the Penn Medicine Center for Evidence-based Practice Last updated April 11, 2020 3:00 pm. Sources rechecked April 11 unless otherwise noted. Key questions Francisco, University of Michigan, University of Washington, Weill-Cornell Medical Center, Zhejiang University Hospital (China) Definition of terms HFNC: High flow nasal cannula. NIPPV: Non-invasive PositivePressureVentilation. This designation may include bilevel positive airway pressure (BiPAP), continuous positive airway pressure (CPAP). About this report A Rapid Guidance Summary is a focused
Safety of bubble nasal intermittent positivepressureventilation (NIPPV) versus bubble nasal continuous positive airway pressure (NCPAP) in preterm infants with respiratory distress. Nasal Intermittent PositivePressureVentilation (NIPPV) is an effective therapy for infants in respiratory distress. We here report the safety of a novel, low-cost, non-electric bubble NIPPV device in comparison with bubble NCPAP. At Paramitha Children's Hospital (Hyderabad, India), preterm (n = 60) neonates with moderate respiratory distress were pragmatically allocated to bubble NCPAP (5-8 cm HO) or bubble NIPPV (P 8-12 cm HO/P 5-8 cm HO) based on staff and equipment availability. Primary outcomes to assess safety included clinically relevant pneumothorax, nasal septal necrosis, or abdominal distention. One
The effect of changing respiratory rate settings on CO(2) levels during nasal intermittent positivepressureventilation (NIPPV) in premature infants. To examine the change in CO, when applying NIPPV with either a low or a high rate in stable premature infants. Prospective, controlled, crossover study. Preterm infants on NIPPV were monitored by tcCO during two rate changes switching every hour to low. Multiplying or dividing the rate settings by three did not significantly change the tcCO readings an hour after the change. These findings could affect the management of ventilation settings of NIPPV in premature infants. ClinicalTrials.gov ID: NCT04836689 , The name of the trial registry: "Influence of Respiratory Rate Settings on CO Levels During Nasal Intermittent PositivePressure
management is crucial, especially for high-risk populations. We conducted the present study to compare the effectiveness of oxygen therapy administered using high-flow nasal cannulae (HFNC) and noninvasive positivepressureventilation (NIPPV) in preventing reintubation among patients receiving prolonged mechanicalventilation (PMV). This single-center, prospective, unblinded randomized controlled trial Effectiveness of high-flow nasal cannulae compared with noninvasive positive-pressureventilation in preventing reintubation in patients receiving prolonged mechanicalventilation. Many intensive care unit patients who undergo endotracheal extubation experience extubation failure and require reintubation. Because of the high mortality rate associated with reintubation, postextubation respiratory
Comparison of extubation success using noninvasive positivepressureventilation (NIPPV) versus noninvasive neurally adjusted ventilatory assist (NI-NAVA). Compare rates of initial extubation success in preterm infants extubated to NIPPV or NI-NAVA. In this pilot study, we randomized 30 mechanicallyventilated preterm infants at the time of initial elective extubation to NI-NAVA or NIPPV in a 1 :1 assignment. Primary study outcome was initial extubation success. Rates of continuous extubation for 120 h were 92% in the NI-NAVA group and 69% in the NIPPV group (12/13 vs. 9/13, respectively, p = 0.14). Infants extubated to NI-NAVA remained extubated longer (median 18 vs. 4 days, p = 0.02) and experienced lower peak inspiratory pressures (PIP) than infants managed with NIPPV throughout
Cardiorespiratory effects of NIV-NAVA, NIPPV, and NCPAP shortly after extubation in extremely preterm infants: A randomized crossover trial. Investigate the cardiorespiratory effects of noninvasive neurally adjusted ventilatory assist (NIV-NAVA), nonsynchronized nasal intermittent positivepressureventilation (NIPPV), and nasal continuous positive airway pressure (NCPAP) shortly after no differences in HRV between modes. A significantly reduced Edi area and breath amplitude, and increased coefficient of variation (CV) of breath amplitude were observed during NIV-NAVA and NIPPV compared to NCPAP. A higher proportion of assisted breaths (99% vs. 51%; p < .001) provided a higher mean airway pressure (MAP; 9.4 vs. 8.2 cmH O; p = .002) with lower peak inflation pressures (PIPs; 14 vs. 16 cmH O
traditionally been treated pharmacologically, with a combination of nitrates, diuretics, morphine, and inotropes. Since the introduction of noninvasive positivepressureventilation (NIPPV), a method of providing mechanicalventilation that does not bypass the upper airway, this modality has been widely used as an important addition to the acute care of ACPE. NIPPV encompasses both CPAP (continuous positive Noninvasive PositivePressureVentilation for Cardiogenic Pulmonary Edema HomeReviewsTherapy (NNT) ReviewsDiagnosis (LR) ReviewsAboutThe NNT, ExplainedThe NNT Rating SystemtheNNT Editorial ProcessThe NNT Intervention QuizAbout theNNT TeamSubmit an articleAccountLoginSign upContactDONATENoninvasive PositivePressureVentilation for Cardiogenic Pulmonary EdemaReduces hospital mortality
Factors associated with adherence to noninvasive positivepressureventilation in amyotrophic lateral sclerosis. This cohort study aimed to investigate the factors associated with noninvasive positivepressureventilation adherence and assess the long-term effects of noninvasive positivepressureventilation adherence in patients with amyotrophic lateral sclerosis (ALS). The medical records of patients with ALS admitted to a tertiary hospital for noninvasive positivepressureventilation initiation were retrospectively reviewed. Pulmonary function parameters, variables of blood gas analysis, the site of symptom onset, the time from onset and diagnosis to noninvasive positivepressureventilation application, ALS Functional Rating Scale-Revised, neurophysiological index, and the length
Effect of High-Intensity vs Low-Intensity Noninvasive PositivePressureVentilation on the Need for Endotracheal Intubation in Patients With an Acute Exacerbation of Chronic Obstructive Pulmonary Disease: The HAPPEN Randomized Clinical Trial. The effect of high-intensity noninvasive positivepressureventilation (NPPV) on the need for endotracheal intubation in patients with an acute
Nasal mask ventilator-delivered versus face maskT-piece resuscitator positivepressureventilation during resuscitation of preterm neonates: a cohort study. To evaluate the clinical impact of nasal mask ventilator-delivered positivepressureventilation (PPV) versus face mask manual T-piece resuscitator PPV during resuscitation of preterm neonates. We conducted a pre-post cohort study in a tertiary neonatal unit, comparing consecutive neonates born 25-28 weeks of gestational age (GA) who received PPV ≤10 min after birth, before and after changing the approach during resuscitation from face mask manual T-piece resuscitator PPV (epoch 1, April 2018-April 2020) to nasal mask ventilator-delivered PPV (epoch 2, May 2020-February 2022). The association between birth epoch and the primary outcome
Nasal Intermittent PositivePressureVentilation During Neonatal Endotracheal Intubation: A Randomized Controlled Trial. This prospective, multicenter, randomized controlled trial aimed to determine whether the use of nasal intermittent positivepressureventilation (NIPPV) during neonatal endotracheal intubation increased the rate of successful intubation without physiological instability during all intubation attempts. In total, 150 infants were randomly assigned to either an NIPPV or standard care group (n = 75 each). The primary outcome was successful intubation without physiological instability (defined as ≥ 20% decline in the peripheral oxygen saturation [SpO] from preintubation value or bradycardia with a heart rate < 100 beats/min) during all intubation attempts. The mean
Positivepressureventilation improves oxygen saturation at altitude during recreational aviation: A pilot study. We investigated whether a commercial bi-level positive airway pressure (BPAP) device, would improve peripheral oxygen saturation (SpO) during recreational aviation up to 12,500 feet without supplemental oxygen. Ten adults with recreational flight experience (age:47 ± 14; female = 5
, Chiesi Pharmaceuticals), as surfactant replacement therapy, on the need for Intermittent PositivePressureVentilation (IPPV) in Neonatal Respiratory Distress Syndrome (NRDS) more precisely by fitting a semi-parametric efficient model adjusted for appropriate covariates. This study is secondary and we re-analyzing data of a published RCT. This RCT was conducted in the NICU of Alzahra Hospital in Tabriz Comparing the Effect of Beractant (Beraksurf™) with That of Poractant Alfa (Curosurf®) on the Need for Intermittent PositivePressureVentilation in Neonatal Respiratory Distress Syndrome by Adopting a Semi-parametric Approach: Re-Analyzing Data of a Ran Randomized controlled trial (RCT) data are analyzed by two challengeable adjusted and non-adjusted approaches. Performing appropriate adjusted
the duration of invasive mechanicalventilation (IMV) in preterm infants, whereas NHFOV and noninvasive intermittent positivepressureventilation (NIPPV) result in fewer reintubations than nasal continuous positive airway pressure (NCPAP). It is unknown whether NHFOV is similarly effective in extremely preterm neonates or in those with more severe respiratory failure (based on the duration of previous Effectiveness of Nasal Continuous Positive Airway Pressure vs Nasal Intermittent PositivePressureVentilation vs Noninvasive High-Frequency Oscillatory Ventilation as Support After Extubation of Neonates Born Extremely Preterm or With More Severe Respir The NASONE (Nasal Oscillation Post-Extubation) trial showed that noninvasive high-frequency oscillatory ventilation (NHFOV) slightly reduces
Effectiveness of a telenursing intervention program in reducing exacerbations in patients with chronic respiratory failure receiving noninvasive positivepressureventilation: A randomized controlled trial. Telenursing for patients with chronic respiratory failure receiving noninvasive positivepressureventilation (NPPV) is an important aid in reducing exacerbations; however
been proven a useful treatment option for SF-deficient neonates. The objective of this study was to explore the impact on the brain (using cerebral near infrared spectroscopy, NIRS) of different LISA methods during NIV, using nasal intermittent positivepressureventilation (NIPPV) for treating neonatal RDS. For this, we used five groups of spontaneously breathing newborn piglets (n = 6/group Structural and haemodynamic evaluation of less invasive surfactant administration during nasal intermittent positivepressureventilation in surfactant-deficient newborn piglets. The most recent approaches to the initial treatment of respiratory distress syndrome (RDS)- involve non-invasive ventilation (NIV) and less-invasive surfactant (SF) administration (LISA). Combining these techniques has
Continuous positive airway pressure (CPAP) vs noninvasive positivepressureventilation (NIPPV) vs noninvasive high frequency oscillation ventilation (NHFOV) as post-extubation support in preterm neonates: protocol for an assessor-blinded, multicenter, ra Various noninvasive respiratory support modalities are available in neonatal critical care in order to minimize invasive ventilation . Continuous positive airway pressure (CPAP) is the more commonly used but noninvasive positivepressureventilation (NIPPV) seems more efficacious in the early post-extubation phase, although it is not clear if NIPPV may influence longterm outcomes. A recently introduced alternative is noninvasive high frequency oscillatory ventilation (NHFOV) which might be especially useful in babies needing high constant
EBNEO Commentary: Non-invasive high-frequency oscillatory ventilation vs nasal continuous positive airway pressure vs nasal intermittent positivepressureventilation as postextubation support for preterm neonates in China: A randomized clinical trial.
Tidal volume delivery during nasal intermittent positivepressureventilation: infant cannula vs. nasal continuous positive airway pressure prongs. To measure tidal volume delivery during nasal intermittent positivepressureventilation with two nasal interfaces: infant cannula and nasal prongs. A single-center crossover study of neonates with mild respiratory distress. Fifteen preterm neonates breaths without patient effort (III). Clinical trial #NCT04326270. Type III breaths delivered no significant tidal volume. No significant difference was measured in relative tidal volume delivery between the interfaces when breath types were matched. Nasal intermittent positivepressureventilation delivers neither clinically nor statistically significant tidal volume with either infant cannula or nasal
Comparison of positivepressureventilation devices during compliance changes in a neonatal ovine model. To compare tidal volume (V) delivery with compliance at 0.5 and 1.5 mL/cmHO using four different ventilation (PPV) devices (i.e., self-inflating bag (SIB), T-Piece resuscitator, Next Step (a novel Neonatal Resuscitator), and Fabian ventilator (conventional neonatal ventilator) using a neonatal piglet model. Randomized experimental animal study using 10 mixed-breed neonatal piglets (1-3 days; 1.8-2.4 kg). Piglets were anesthetized, intubated, instrumented, and randomized to receive positivepressureventilation (PPV) for one minute with a SIB with or without a respiratory function monitor (RFM), T-Piece resuscitator with or without an RFM, Next Step, and Fabian Ventilator with both