Guideline "TransientGlobalAmnesia (TGA)" of the German Society of Neurology (Deutsche Gesellschaft f'r Neurologie): S1-guideline In 2022 the DGN (Deutsche Gesellschaft für Neurologie) published an updated TransientGlobalAmnesia (TGA) guideline. TGA is characterized by a sudden onset of retrograde and anterograde amnesia for a period of one to a maximum of 24 h (with an average of 6 to 8 h
The link between reversible cerebral vasoconstriction syndrome and transientglobalamnesia. Reversible cerebral vasoconstriction syndrome (RCVS) and transientglobalamnesia (TGA) are acute and self-limiting intra-cerebral conditions. Although previously studied as independent phenomena, there are increasing reports of co-occurrence of these two pathologies. We report a 55-year-old male who
Acute coronary syndrome and transientglobalamnesia with sumatriptan. Triptans are potent serotoninergic vasoconstrictors. They are generally avoided in elderly patients age greater than 65 or in patients with a history of CAD. Although there are reported cases of Acute Coronary Syndrome (ACS) or TransientGlobalAmnesia (TGA) in patients after ingesting therapeutic doses of triptan . Neurology was consulted for her amnesia and diagnosed her with TransientGlobalAmnesia (TGA). They recommended discontinuing sumatriptan and beginning topiramate as a prophylactic therapy. There is an increasing number of reports delineating sumatriptan's adverse effects. Emergency medicine physicians should promptly recognize the toxic effects and adverse reactions from triptans. Sumatriptan-induced
Factors Associated With Risk of Recurrent TransientGlobalAmnesia. Transientglobalamnesia (TGA) is usually considered a benign event with a low recurrence rate. However, recurrence rates vary considerably among studies and there are no known risk factors for TGA. To examine risk factors for the recurrence of TGA. This retrospective cohort study involved medical record review of patients
Factors determining recurrence in transientglobalamnesia. Aetiology of transientglobalamnesia (TGA) remains uncertain, though many have been proposed, including ischaemic, migrainous or epileptic pathologies. We attempted to determine risk factors for TGA, as well as prognostic factors that may cause recurrence. We evaluated clinical history, family history and magnetic resonance diffusion
Long-Term Risk of Stroke After TransientGlobalAmnesia in Two Prospective Cohorts. Background and Purpose- Transientglobalamnesia (TGA) is known as a benign syndrome, but recent data from neuroradiological studies support an ischemic cause in some cases, which might suggest an increased susceptibility to cerebrovascular events. We determined the long-term risk of stroke after a first TGA in 2
Subarachnoid hemorrhage after transientglobalamnesia caused by cerebral venous congestion: case report. Transientglobalamnesia is reported to be caused by cerebral venous congestion. Internal jugular venous flow reversal in particular with the Valsalva maneuver leads to cerebral venous congestion. In addition, Valsalva maneuver can also induce subarachnoid hemorrhage. Transientglobalamnesia and subarachnoid hemorrhage might have common a pathophysiology in cerebral venous congestion. We report here the case of a 57-year-old woman who twice experienced convexal subarachnoid hemorrhage just after straining at stool following an episode of transientglobalamnesia. Digital subtraction angiography showed left temporal congestion. Left jugular vein ultrasonography revealed reflux
Risk factors of transientglobalamnesia: Three case reports. Transientglobalamnesia (TGA) is characterized by a sudden onset of anterograde and retrograde amnesia, sometimes associated with mild subclinical neuropsychological deficits and vegetative symptoms, lasting for days after the episode. Migraine history, cardiovascular risk factors, and emotional stress are considered possible risk
TransientGlobalAmnesia Deteriorates the Network Efficiency of the Theta Band. Acute perturbation of the hippocampus, one of the connector hubs in the brain, is a key step in the pathophysiological cascade of transientglobalamnesia (TGA). We tested the hypothesis that network efficiency, meaning the efficiency of information exchange over a network, is impaired during the acute stage of TGA
Transientglobalamnesia: Minor inconvenience or early warning sign? Transientglobalamnesia (TGA) is a clinical diagnosis and is often a diagnosis of exclusion. However, despite the benign nature of this condition, it has been associated with underlying life-threatening medical conditions (e.g., myocardial infarction, dissecting aortic aneurysm, arrhythmias). Our case report highlights
A case of recurrent transientglobalamnesia: don’t forget the hippocampal punctuate diffusion restriction Transientglobalamnesia (TGA) is a syndrome characterized by reversible impairment of short-term memory. TGA itself is a benign disease, however, it is reasonable to investigate and exclude sinister causes of global amnesia; such as stroke or a seizure activity. A case of TGA is presented
Temporary Memory Steal: TransientGlobalAmnesia Secondary to Nephrolithiasis Transientglobalamnesia (TGA) is typified by an abrupt and transient anterograde amnesia, "with repetitive questioning and often variable retrograde amnesia persisting up to 24 hours." A 54-year-old male presented to our emergency department with paroxysms of left-sided flank pain, suggestive of renal colic. Computed
Relationship between Cytotoxicity in the Hippocampus and an Abnormal High Intensity Area on the Diffusion-weighted Images of Three Patients with TransientGlobalAmnesia Objective An abnormal high intensity area (HIA) on diffusion-weighted imaging (DWI) indicates the presence of cytotoxic edema and has been reported to be observed in the hippocampus of patients with transientglobalamnesia (TGA
PRevalence Of TransientGlobalAmnesia in Obstructive Sleep Apnea Syndrome Amnesic stroke is an amnestic syndrome lasting less than 24 hours characterized by the occurrence of anterograde amnesia often associated with retrograde amnesia, the pathophysiology of which is still poorly understood at present. A recent study on a small sample size (N=29) highlighted an association between obstructive
Long-Term Outcome in Patients With TransientGlobalAmnesia: A Population-Based Study. To study the long-term risk of cerebrovascular events, seizures, and cognitive impairment in patients with transientglobalamnesia (TGA). Data for all patients diagnosed with possible TGA in Olmsted County, Minnesota, between January 1, 1985, through December 31, 2010, were retrieved from the Rochester Epidemiology Project database. Transientglobalamnesia was defined clinically. End points were cerebrovascular event (stroke or transient ischemic attack), seizure, or cognitive impairment (mild cognitive impairment or dementia) during follow-up. End points were studied using Kaplan-Meier survival plots and log-rank test. A total of 221 patients with TGA were identified and 221 age- and sex-matched controls
Cortical morphology in patients with transientglobalamnesia This study evaluated alterations in cortical morphology in patients with transientglobalamnesia (TGA). Diagnoses of TGA occurred at our hospital. Evaluation involved a structured interview to obtain clinical information and a brain magnetic resonance imaging scan. We analyzed whole-brain T1-weighted MRI data using FreeSurfer 5.1
Transientglobalamnesia: current perspectives Transientglobalamnesia (TGA) is a clinical syndrome characterized by the sudden onset of an extraordinarily large reduction of anterograde and a somewhat milder reduction of retrograde episodic long-term memory. Additionally, executive functions are described as diminished. Although it is suggested that various factors, such as migraine, focal
Reversible Cerebral Vasoconstriction Syndrome Presenting with TransientGlobalAmnesia A 65-year-old man who had been diagnosed with transientglobalamnesia (TGA) 15 years previously was admitted to hospital with complaints of amnesia and headache. His symptoms improved on day-2. The initial brain MRI and electroencephalography findings were normal. He was diagnosed with a recurrence of TGA