surgery, orchiectomy (ORX), ORX + anastrozole (AN; aromatase inhibitor), ORX + testosterone-enanthate (TE, 7.0 mg/wk), ORX + TE + AN, ORX + trenbolone-enanthate (TREN; nonaromatizable, nonestrogenic testosterone analogue; 1.0 mg/wk), or ORX + TREN + AN. ORX animals exhibited histomorphometric indices of high-turnover osteopenia and reduced cancellous bone volume compared with Shams. Both TE and TREN
they are not widely used in medicine.[66] Boldenone undecylenate and trenbolone acetate are used in veterinary medicine.[1]Designer steroids are AAS that have not been approved and marketed for medical use but have been distributed through the black market.[71] Examples of notable designer steroids include 1-testosterone (dihydroboldenone), methasterone, trenboloneenanthate, desoxymethyltestosterone