Topical estrogen, testosterone, and vaginal dilator in the prevention of vaginalstenosis after radiotherapy in women with cervical cancer: a randomized clinical trial. We aimed to evaluate the effects of different therapeutic options to prevent the evolution of vaginalstenosis after pelvic radiotherapy in women with cervical cancer. open-label randomized clinical trial of 195 women, stage I -IIIB, aged 18-75 years, using topical estrogen (66), topical testosterone (34), water-based intimate lubricant gel (66), and vaginal dilators (29) to assess the incidence and severity of vaginalstenosis after radiotherapy at UNICAMP-Brazil, from January/2013 to May/2018. The main outcome measure was vaginalstenosis assessed using the Common Terminology Criteria for Adverse Events (CTCAE) scale
The Use of Singapore Flaps for Vaginal Reconstruction in Women with VaginalStenosis with Obstetric Fistula: A Surgical Technique. Gynecologic and plastic surgeons collaborate to improve vaginal reconstruction for women with vaginalstenosis and obstetric fistula. As these cases occur typically in low-resource settings, the Singapore flap is a useful technique given its reliability, safety, ease
Radiation-induced vaginalstenosis: current perspectives Treatment of gynecological cancer commonly involves pelvic radiation therapy (RT) and/or brachytherapy. A commonly observed side effect of such treatment is radiation-induced vaginalstenosis (VS). This review analyzed the incidence, pathogenesis, clinical manifestation(s) and assessment and grading of radiation-induced VS. In addition
Is the use of a vaginalstenosis dilator after radiotherapy effective? A systematic review PROSPERO International prospective register of systematic reviews Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied
Postpartum VaginalStenosis Due to Chemical Vaginitis Acquired vaginalstenosis is a rare obstructing anomaly, which can be caused by use of chemicals in the vagina. A 21-year-old gravida 1 para 1, presented with secondary amenorrhea and inability to have sexual intercourse, after normal spontaneous vaginal delivery complicated by post partum bleeding. The delivery was conducted by untrained dyspareunia. Post partum vaginalstenosis due to chemical vaginitis is rare. These cases can be prevented by adequate training of untrained health care workers.
Dosimetric Predictors of Radiation-Induced VaginalStenosis After Pelvic Radiation Therapy for Rectal and Anal Cancer. Although vaginalstenosis (VS) is a recognized toxicity in women who receive pelvic radiation therapy (RT), the relationship between RT dose and the volume and extent of toxicity has not been analyzed. We modeled this relationship to identify predictors of VS. We evaluated 54 of vaginal volume to a low dose may be important. When gEUD (a = -1) was <35 Gy and the mean vaginal dose was <43 Gy, severe VS was reduced (P=.02). A 1-year analysis suggests increasingly negative D values with increasing mean dose. However, patients with compliance <40% were more likely to have toxicity. Vaginalstenosis is influenced by multiple RT dose-volume characteristics. Mean dose and gEUD
Role of vaginal pallor reaction in predicting late vaginalstenosis after high-dose-rate brachytherapy in treatment-naive patients with cervical cancer To assess actual rates of late vaginalstenosis and identify predisposing factors for complications among patients with previously untreated cervical cancer following high-dose-rate brachytherapy. We performed longitudinal analyses of 57 patients using the modified Dische score at 6, 12, 18, 24, 36, and 60 months after treatment, which consisted of 15 interstitial brachytherapys and 42 conventional intracavitary brachytherapys, with a median follow-up time of 36 months (range, 6 to 144 months). More than half of the patients developed grade 1 (mild) vaginalstenosis within the first year of follow-up, and grade 2 (97.5%, moderate) to grade 3
Fat Grafting for VaginalStenosis in Gynaelogical Cancer The GRASS study looks at performing a technique called "Fat Tissue Grafting" to assess whether it can reduce the side effects of vaginalstenosis effects and improve the sexual function of participants who wish to preserve penetrative sexual function Vaginalstenosis is a common sequelae of radiotherapy treatment for cervical cancer vaginalstenosis after radiotherapy treatment for advanced cervical cancer, by the Gynaecological and Plastic surgical teams at the Royal Marsden Hospital (RM). The fat tissue was harvested and processed using the method as described and injected into the vagina area (rectovaginal wall) with the aim being to generate more elasticity and improve the quality of the vaginal tissue. As a result
Physical therapy resources applied in the vaginalstenosis treatment after radiotherapy in cervical cancer patients: a systematic review and meta-analysis. Physical therapy resources applied in the vaginalstenosis treatment after radiotherapy in cervical cancer patients: a systematic review and meta-analysis. Print | PDF PROSPERO This information has been provided by the named contact
Quantifying Radiation Induced VaginalStenosis Radiation (RT) affects the vagina by narrowing, tightening and scarring, termed vaginalstenosis (VS). VS occurs in up to 88% of patients treated with radiation for cervical cancer. VS is not well characterized in measurements. There is a lack of understanding of how short and tight the vagina becomes after RT. This study will use specific of vaginalstenosis.
Influence of diagnostic methods for vaginalstenosis in vaginal dilators compliance Influence of diagnostic methods for vaginalstenosis in vaginal dilators compliance Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information
An Enhanced Vaginal Dilator to Reduce Radiation-Induced VaginalStenosis This is a randomized control trial aimed to decreased radiation-induced vaginalstenosis in patients with endometrial or cervical cancer treated with post-operative external beam radiation therapy with or without brachytherapy. The intervention is an enhanced vaginal dilator model, including a silicone band placed cancer. Radiation-induced vaginalstenosis is a well recognized complication of radiation therapy and can result in painful, inadequate pelvic exams and sexual dysfunction. Current recommendations to prevent and manage vaginalstenosis include regular use of vaginal dilators, with our institutional recommendation being three times weekly for 10 minutes. Compliance varies among studies but is generally
approach due to position distant from the US probe and free fluid. Visualization TAUS may also be better than TVUS in select other circumstances (patient discomfort, large fibroids, surgical changes) or when TVUS is uncomfortable or inappropriate (post-treatment vaginalstenosis/fibrosis, juvenile age, sexually naïve patient). US Pelvis Transvaginal A combined transabdominal