"Wolff's law" from_date:2012

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                            1
                            2025National Hemophilia Foundation
                            Trip Score
                            NarrativeNarrative based
                            EvidenceEvidence based
                            ?
                            ; as with Wolff’s Law, with increased mechanical loading, the bones will become stronger from the cancellous bone to the outer cortical layer.30, 31 This agrees with the Center for Disease Control’s (CDC) recommendation for children and adolescents to participate in aerobic, strengthening and bone building exercises as part of their regular physical activity.32 Furthermore, bone banking, the creation Resistance Training on Physical Function and Pain in People With Hemophilia. Physical Therapy. 2020;100(9):1632-44. 29. Benedetti MG, Furlini G, Zati A, Letizia Mauro G. The Effectiveness of Physical Exercise on Bone Density in Osteoporotic Patients. Biomed Res Int. 2018;2018:4840531. 30. Frost HM. Wolff's Law and bone's structural adaptations to mechanical usage: an overview for clinicians. Angle Orthod
                            2
                            2025European Spine Journal
                            biomechanical adaptation according to Wolff's law. It is more pronounced in well-fused segments with a greater degree of lordosis and may indicate successful fusion and good sagittal alignment restoration. Further research is needed to evaluate its long-term clinical implications.
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                            3
                            Cementless Reverse Total Shoulder Arthroplasty Implantation With Humeral Matchstick Autograft Augmentation: Early Radiographic Outcomes. Humeral-sided complications account for up to 21% of all revision Reverse Total Shoulder Arthroplasty (RTSA) surgeries. Stress shielding with large bulky stems can lead to proximal bone resorption per Wolff's law, complicating further surgeries. Previously
                            4
                            2020Medscape
                            program.Therefore, under normal circumstances, bone appears able to keep up with necessary repairs without manifesting clinically significant injury as it remodels in accordance with Wolff's law. However, when a bone's reparative and adaptive capacity is overwhelmed by chronic overload, damage can begin to accumulate. If allowed to progress, this multifactorial process may eventually result in a stress
                            5
                            2020Clinics in Sports Medicine
                            to injury than bone. Although remodeling can correct for even moderate deformities if sufficient growth potential exists, remodeling cannot return the child to normal anatomy in many cases. Remodeling depends on intact periosteum, a nearby growing physis, and competent ligaments to direct remodeling via Hueter-Volkmann and Wolff's laws.
                            6
                            that had a posterior surgical approach, LF is associated with a larger interval regression in disc-osteophyte complex size compared to laminoplasty. This is likely related to the loss of motion of the cervical spine after surgery as governed by Wolff's law and the Heuter-Volkmann's principle. Although the decompressive effect of LF and laminoplasty is primarily related to the dorsal drift of the spinal
                            7
                            2016Spine
                            Overview of Biologics. Biologics in the appropriate biomechanical environment provide viable bone graft substitutes for repair of injured bone while promoting bone formation and osseointegration. Surgeons must recall the basics of bone structure, the principles of Wolff's law, and the components and steps of new bone formation to optimize the fusion environment and to maximize patient outcomes.
                            8
                            2016Journal of morphology
                            Trabecular bone of precocials at birth; Are they prepared to run for the wolf(f)? Bone is a dynamic tissue adapting to loading according to "Wolff's law of bone adaptation." During very early life, however, such a mechanism may not be adequate enough to adapt to the dramatic change in environmental challenges in precocial species. Their neonates are required to stand and walk within hours after
                            9
                            2016Bone and Joint Journal
                            entity. This 'bone-healing unit' produces a physiological response to its biological and mechanical environment, which leads to the normal healing of bone. This tissue responds to mechanical forces and functions according to Wolff's law, Perren's strain theory and Frost's concept of the "mechanostat". In response to the local mechanical environment, the bone-healing unit normally changes with time
                            10
                            2016Interface focus
                            Experimental studies of bone mechanoadaptation: bridging in vitro and in vivo studies with multiscale systems Despite advancements in technology and science over the last century, the mechanisms underlying Wolff's law-bone structure adaptation in response to physical stimuli-remain poorly understood, limiting the ability to effectively treat and prevent skeletal diseases. A challenge to overcome
                            11
                            of non-union of tibia. In conservatively treated cases of fracture, both bones of leg, non-union of tibia may coexist with compensatory hypertrophy of fibula to the extent that, it becomes main weight bearing bone of the leg. We are presenting here two cases of natural tibialization of fibula along with nonunion tibia. Our article supports the theory of Wolff's law.
                            14
                            2014eMedicine Surgery
                            , and the distinction between the nucleus and the anulus becomes blurred. The proteoglycan, water, and noncollagenous protein concentrations decrease, while the collagen concentration increases. The increase in collagen concentration is more pronounced in the nucleus and in the posterior quadrants of the disk. It is more pronounced with age and moves caudally in the lumbar spine (similar to the Wolff law
                            15
                            2014eMedicine Surgery
                            or the posterolateral gutter approaches, it leaves both the back muscles and nerves undisturbed. Another advantage is that placing the graft in the front of the spine puts it in compression, and bone in compression tends to fuse better, according to the Wolff law. However, because of the reliance on compression for achieving solid fusion, osteoporosis is a contraindication for ALIF.Major risks of ALIF include
                            16
                            2014eMedicine.com
                            without manifesting clinically significant injury as it remodels in accordance with Wolff's law. However, when a bone's reparative and adaptive capacity is overwhelmed by chronic overload, damage can begin to accumulate. If allowed to progress, this multifactorial process may eventually result in a stress fracture.Animal studies have demonstrated that bone subjected to repetitive cyclical loading
                            19
                            2014eMedicine Surgery
                            , and the distinction between the nucleus and the anulus becomes blurred. The proteoglycan, water, and noncollagenous protein concentrations decrease, while the collagen concentration increases. The increase in collagen concentration is more pronounced in the nucleus and in the posterior quadrants of the disk. It is more pronounced with age and moves caudally in the lumbar spine (similar to the Wolff law
                            20
                            2014eMedicine Surgery
                            or the posterolateral gutter approaches, it leaves both the back muscles and nerves undisturbed. Another advantage is that placing the graft in the front of the spine puts it in compression, and bone in compression tends to fuse better, according to the Wolff law. However, because of the reliance on compression for achieving solid fusion, osteoporosis is a contraindication for ALIF.Major risks of ALIF include