Outcomes of Mechanical Thrombectomy for AcuteLimbIschemia at a Tertiary Referral Center. Acutelimbischemia (ALI) harbors high risk of limb loss and mortality. We reviewed the use and outcomes of mechanical thrombectomy devices in the management of ALI at a tertiary referral center. ALI cases with duration of symptoms <2 weeks and treated with mechanical thrombectomy at a tertiary referral
Comparison of open and endovascular therapy for infrainguinal acutelimbischemia in the era of percutaneous thrombectomy. Endovascular treatment of acutelimbischemia (ALI), primarily consisting of catheter-directed thrombolysis (CDT), has been shown to reduce mortality without affecting limb salvage. Percutaneous thrombectomy (PT) devices have expanded endovascular approaches while decreasing
Single Center Experience with the JETi Hydrodynamic Thrombectomy System for AcuteLimbIschemia. Acutelimbischemia (ALI) remains a vascular emergency with high morbidity and mortality. While the JETi Hydrodynamic Thrombectomy System (Abbott, Abbott Park, IL) offers a percutaneous approach to fragment and aspirate thrombus in patients with arterial occlusions, data on its efficacy and safety
Percutaneous Thrombectomy for AcuteLimbIschemia is Associated With Equivalent Limb and Mortality Outcomes Compared to Open Thrombectomy. Acutelimbischemia (ALI) carries a 15-20% risk of combined death or amputation at 30 days and 50-60% at 1 year. Percutaneous mechanical thrombectomy (PT) is an emerging minimally invasive alternative to open thrombectomy (OT). However, ALI thrombectomy cases
Multi-Level Thrombotic/Embolic Burden and Its Role in Sex-Related Outcomes in AcuteLimbIschemia (ALI). The impact of sex upon outcomes in acutelimbischemia (ALI) remains disputed. We aim to quantify the effect of sex upon amputation-free survival (AFS) after a percutaneous-first approach for ALI. Two-center retrospective review of ALI managed via a percutaneous-first approach. Demographics
Clinical outcomes of acutelimbischaemia caused by femoropopliteal stent thrombosis. Although femoropopliteal-specific stents have durable patency, stent thrombosis (ST) may occur, which can lead to acutelimbischaemia (ALI). We aimed to investigate the clinical features and outcomes of ALI caused by femoropopliteal ST in patients with lower extremity artery disease. This multicentre
Contemporary Practice Patterns and Outcomes of Endovascular Revascularization of AcuteLimbIschemia. Acutelimbischemia is a vascular emergency associated with high rates of limb loss and mortality. As the use of endovascular techniques increases, estimation of rates and predictors of adverse outcomes remains needed. This study sought to assess contemporary outcomes and predictors of adverse events following endovascular treatment of acutelimbischemia in a nationwide, multicenter registry. Patients who had peripheral vascular intervention performed for the indication of acutelimbischemia in National Cardiovascular Data Registry Peripheral Vascular Intervention Registry between 2014 and 2020 were included. The primary outcome was a composite of all-cause mortality and major amputation
Retracted: Effect of AcuteLimbIschemia on the Mortality of Patients with Extracorporeal Membrane Oxygenation Established by Femoral Vein-Arterial Catheterization and Analysis of Related Risk Factors. [This retracts the article DOI: 10.1155/2021/3471764.].
The Management of Patients with Popliteal Artery Aneurysms Presenting with AcuteLimbIschemia. Endovascular popliteal artery aneurysm (PAA) repair has acceptable outcomes compared to open repair for elective therapy. Endovascular repair for urgent PAA causing acutelimbischemia (ALI) has not been well studied. This project compares outcomes of urgent endovascular and open repair of PAA
Incidence and Predictors of AcuteLimbIschemia in Patients With Acute Myocardial Infarction-Insight from National Readmission Database. Acutelimbischemia (ALI) has been a rare complication of acute myocardial infarction (AMI), however, with the increasing use of mechanical circulatory devices it is seen more frequently. The incidence and predictors of ALI in patients with AMI in contemporary
Safety and Efficacy of Mechanical Aspiration Thrombectomy at 30-days for Patients with Lower Extremity AcuteLimbIschemia (STRIDE). Acutelimbischemia is associated with high rates of amputation and consequent morbidity and mortality. The objective of this study is to report on the safety and efficacy of aspiration thrombectomy using the Indigo® Aspiration System in patients with lower extremity acutelimbischemia (LE-ALI). The STRIDE study was an international, multicenter, prospective, study that enrolled 119 participants presenting with LE-ALI. Patients were treated firstline with mechanical thrombectomy using the Indigo® Aspiration System, prior to stenting or angioplasty, or other therapies as determined by treating physician. The primary endpoint was target limb salvage at 30
High risk and low prevalence diseases: Acutelimbischemia. Acutelimbischemia is a rare but serious condition that carries with it a high rate of morbidity and mortality. This review highlights the pearls and pitfalls of acutelimbischemia, including presentation, diagnosis, and management in the emergency department (ED) based on current evidence. Acutelimbischemia is defined as a sudden injury. Patients with acutelimbischemia most commonly present with severe pain and sensory changes in the initial stages, with prolonged ischemia resulting in weakness, sensory loss, and color changes to the affected limb. The emergency clinician should consult the vascular specialist as soon as ischemia is suspected, as the diagnosis should be based on the history and examination. Computed
COVID-associated acutelimbischemia during the Delta surge and the effect of vaccines. Hypercoagulability is common in severe acute respiratory syndrome coronavirus 2 and has been associated with arterial thrombosis leading to acutelimbischemia (ALI). Our objective was to determine the outcomes of concurrent coronavirus disease 2019 (COVID-19) infection and ALI, particularly during the Delta
Incidence and predictors of acutelimbischemia in acute myocardial infarction complicated by cardiogenic shock. To describe the incidence and predictors of acutelimbischemia (ALI) in patients with acute myocardial infarction (AMI) complicated by cardiogenic shock (CS). Patients with index hospitalizations for AMI complicated by cardiogenic shock from 2016 to 2019 in the US National
Reduction in AcuteLimbIschemia With Rivaroxaban Versus Placebo in Peripheral Artery Disease After Lower Extremity Revascularization: Insights From VOYAGER PAD Patients with peripheral artery disease (PAD) are at heightened risk of acutelimbischemia (ALI), a thrombotic event associated with amputation, disability, and mortality. Previous lower extremity revascularization (LER) is associated
Among patients undergoing lower limb revascularization for PAD, does addition of low dose rivaroxaban (2.5mg twice daily) to aspirin'clopidogrel lower risk of acutelimbischemia, major amputation for vascular causes, MI, ischemic stroke, or CV mortality VOYAGER-PADJump to navigationJump to searchPublishedBonaca M, et al. "Rivaroxaban in Peripheral Artery Disease after Revascularization". The New patients undergoing lower limb revascularization for PAD, does addition of low dose rivaroxaban (2.5mg twice daily) to aspirin±clopidogrel lower risk of acutelimbischemia, major amputation for vascular causes, MI, ischemic stroke, or CV mortality or increase bleeding, when compared to placebo?Bottom LineAmong patients undergoing lower limb revascularization for PAD, the addition of low dose rivaroxaban
Young patients without prior vascular disease are at increased risk of limb loss and reintervention after acutelimbischemia. The objective of the present study was to categorize the presentation and treatment of acutelimbischemia (ALI) in young patients and compare the adverse outcomes after revascularization compared with that of older patients. All the patients who had presented to a multi
Acutelimbischemia among patients with COVID-19 infection. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been associated with thrombotic complications such as deep vein thrombosis or stroke. Recently, numerous cases of acutelimbischemia (ALI) have been reported although pooled data are lacking. We systematically searched PubMed, Embase, Scopus, and the Cochrane
Acutelimbischemia in an adolescent with COVID-19 and systemic scleroderma: a case report. Juvenile Scleroderma is a rare autoimmune disease of the connective tissue. Its concurrence with COVID-19 can lead to limb ischemia as both disease entities are pro-inflammatory and pro-thrombotic. To date, there is no case report describing the symptomatology and course of disease in patients with juvenile Scleroderma and COVID-19. An adolescent with acutelimbischemia presented with a history of generalized hypo-and-hyperpigmented skin lesions and mild, non-productive cough. She tested positive for SARS-CoV-2 on nasopharyngeal swab RT-PCR. Further work-up revealed elevated anti-phospholipid antibodies, anti-nuclear antibody, and D-dimer; low Protein S activity; and evidence of peripheral
Outcomes of acutelimbischemia in COVID-19. The inflammatory cascade caused by severe acute respiratory syndrome coronavirus 2 infection may result in arterial thrombosis and acutelimbischemia (ALI) with devastating consequences. The aims of this study were to compare outcomes of ALI in the lower extremities in patients with and without coronavirus disease 2019 (COVID-19), and to determine if ALI development in the context of COVID-19 portends a worse prognosis compared with COVID-19 without ALI. Queries were built on TriNetX, a federated network of health care organizations across the United States that provides de-identified patient data. International Classification of Diseases, 10th revision diagnostic codes were used to identify patients with acutelimbischemia of the lower