Novel and unusual USP6 fusion partners in aneurysmalbonecyst and their role in pathogenesis and histopathological evaluation of this disease. The purpose of this study is to report novel and unusual fusion partners in aneurysmalbonecysts (ABCs). These findings may be useful in routine diagnostics as well as in studying the biology of -related disorders. A cohort of seven patients diagnosed
Metatarsal AneurysmalBoneCysts Treated With En Bloc Resection and Reconstruction With Fibular Allograft. Treatment of Primary metatarsal aneurysmalbonecyst (ABC) with curettage and bone grafting unfortunately has a high recurrence rate, particularly in short tubular bones. This study presents a 16-year experience treating ABCs in the bones of the foot at an orthopaedic oncology referral
Aneurysmalbonecyst of the temporal bone presenting with reversible vestibular impairment. Aneurysmalbonecysts are expansile benign lesions associated with compressive destruction and obscure pathogenesis. The most common sites of temporal bone involvement are the petrous apex, squamous portions and mastoid. This paper reports a right temporal aneurysmalbonecyst in a 51-year-old man who presented clinically with facial palsy, and hearing loss and impaired vestibular function. Magnetic resonance imaging and computed tomography findings were consistent with a diagnosis of aneurysmalbonecyst. Inter-operative findings showed that the lesion had caused compressive damage to the internal auditory canal. Following surgical excision, the patient experienced vertigo, indicating recovery
Giant cell tumor of bone with secondary aneurysmalbonecyst does not have a higher risk of local recurrence. Fluid-fluid levels (FFLs) is found in 10%-16% of giant cell tumor of bone (GCTB), and the presence of FFLs raises the suspicion of GCTB with secondary aneurysmalbonecyst (ABC), which can lead to increased intraoperative bleeding and, blurring the operative field, be associated
Aneurysmalbonecysts: A UK wide tumor center experience. This multicenter retrospective series of consecutive extra-spinal aneurysmalbonecysts aims to identify risk factors for treatment failure. Aneurysmalbonecysts treated within seven collaborating centers with over 12-months follow-up were eligible for inclusion. Survival analyses were performed to identify variables associated procedure, 47% required no further treatment. Patients under 13 years (log-rank p = 0.006, HR 2.3, p = 0.011) and those treated who had limited curettage (log-rank p = 0.001, HR 2.7, p = 0.002) had a higher risk of recurrence/persistence. There is a high risk of recurrence following surgical treatment for aneurysmalbonecysts and this risk is higher in young patients. However, the cyst heals
Aneurysmalbonecyst: Is selective arterial embolization effective as curettage and bone grafting? Aneurysmalbonecyst (ABC) is a lytic benign bone lesion representing about 1% of all primary bone tumors. Method to treat ABC's have developed over time. The standard of care cure for ABC has been curettage with or without bone grafting of the defect but is burdened by recurrence rates
Does cryotherapy decrease the local recurrence rate in the treatment of an AneurysmalBoneCyst? A comparative assessment. Curettage with or without the use of adjuvants is standard of care in treatment of an AneurysmalBoneCyst (ABC). Historically, our approach combined curettage, high speed burr drilling and cryo-ablation. However, treatments varied based on age, tumor location and surgeon
Aneurysmalbonecyst of the pelvis and sacrum: a single-center study of 17 cases. The aneurysmalbonecyst (ABC) is a benign, but locally aggressive cystic lesion of the bone. It usually occurs in the metaphysis of long bones of adolescents and young adults but can also affect the pelvis. This single-center study is a retrospective review of 17 patients with primary ABCs of the pelvis
Primary aneurysmalbonecysts. The aim of this study was to analyze the complications and outcomes of treatment in a series of previously untreated patients with a primary aneurysmalbonecyst (ABC) who had been treated by percutaneous sclerosant therapy using polidocanol. Between January 2010 and December 2016, 56 patients were treated primarily with serial intralesional sclerosant injections
Huge aneurysmalbonecyst secondary to giant cell tumor of the hand phalanx: a case report and related literature. Aneurysmalbonecyst (ABC) secondary to Giant Cell Tumor of bone (GCT) is a rare lesion, of which the incidence is about 0.011 to 0.053 per 100,000 every year. There are only a few previous case reports, and most of them occur in the spine, long bones or flat bones. We report one as aneurysmalbonecyst secondary to giant cell tumor, 13 × 8 × 6 cm, with no local infiltration observed. No recurrence and metastasis occurred 18 months after the operation, and the patient recovered well. In this report, we discuss the etiology, diagnosis, differentiation, and management of AneurysmalboneCyst secondary to Giant Cell Tumor of bone, and review previous case studies.
Tailored treatment of aneurysmalbonecyst of the scapula: en bloc resection for the body and extended curettage for the neck and acromion. The acromion and neck of the scapula are essential components of shoulder function, but the body section is less critical. We treated aneurysmalbonecysts (ABCs) of the neck and acromion with extended curettage and ABCs of the body with en bloc resection
Aneurysmalbonecysts of the clavicle: a comparison of extended curettage and segmental resection with bone reconstruction. Although curettage of an aneurysmalbonecyst (ABC) of the clavicle has a high rate of local recurrence, segmental resection is often avoided for treatment as it causes functional impairment and shoulder deformity. We evaluated the rate of local recurrence and functional
Giant cell tumors combined with secondary aneurysmalbonecysts are more likely to develop postoperative recurrence: A retrospective study of 256 cases. The epidemiology and clinicopathology of aneurysmalbonecysts (ABCs) secondary to giant cell tumors of bone (GCTBs) have been well documented in the previous literature. However, reports on whether secondary ABCs could affect the postoperative
Symptomatic aneurysmalbonecysts of the spine: clinical features, surgical outcomes, and prognostic factors. The aim of the study was to report the long-term outcomes and analyze the potential prognostic factors that may contribute to symptomatic patients with aneurysmalbonecyst (ABC) of the spine undergoing surgical treatments. A retrospective analysis of consecutive patients with ABCs
Aneurysmalbonecyst: results of an off label treatment with Denosumab. The treatment of aneurysmalbonecysts (ABCs) has evolved and less invasive methods have been tried. Denosumab is a monoclonal antibody which inhibits osteoclasts. It has been shown to be effective in giant cell tumour of bone (GCT) of bone and hence promises some effect also in ABC. We report on 6 patients treated
A case report of aneurysmalbonecyst of the thoracic spine treated by serial anterior and posterior fusion. Aneurysmalbonecyst (ABC) is a benign, reactive, non-neoplastic, proliferative, highly vascular osseous lesion. Because of the rarity of aggressive ABC cases, diagnostic and treatment protocols remain controversial and problematic. Treatment of ABC includes surgery, radiotherapy
Treatment of aneurysmalbonecysts using endoscopic curettage. Although aneurysmalbonecysts (ABCs) are benign tumours, they have the potential to be locally aggressive. Various treatment approaches, such as en bloc resection, open curettage, radiotherapy, sclerotherapy, and embolization have been proposed, but the most appropriate treatment should be selected after considering the risk
Aneurysmalbonecyst of the clavicle: a series of 13 cases. Aneurysmalbonecyst (ABC) is a benign but locally aggressive bone tumor occurring most commonly in the first 2 decades of life. The clavicle is a rare location for tumors, and ABCs of the clavicle have been sparsely described in the literature. We present the largest known series of ABCs of the clavicle to describe this rare condition
Metacarpal AneurysmalBoneCyst En Bloc Resection Reconstructed With Osteoarticular Allograft. Aneurysmalbonecysts are large lytic lesions that appear most often around metaphyseal bone. The lesions are locally aggressive with high recurrence rates. Therefore, wide resection is commonly necessary, leading to challenging reconstruction of the defect, especially when the articular surface is involved. We present a case of an aneurysmalbonecyst of the fourth metacarpal, treated with an en bloc resection and reconstruction with a metacarpal osteoarticular allograft. At 8 years after surgery, the patient has shown no signs of recurrence, but radiographic articular reabsorption was noted. However, the patient showed an excellent outcome with a satisfactory active range of motion and grip