Total anklereplacement versus ankle arthrodesis for patients aged 50 85 years with end-stage ankle osteoarthritis: the TARVA RCT Text onlyJournals LibraryNHS NIHR - National Institute for Health and Care ResearchSelectEMEGHRHSDRHTAPGfARPHR AdvancedJournalsEfficacy and Mechanism EvaluationGlobal Health ResearchHealth and Social Care Delivery ResearchHealth Technology AssessmentProgramme Grants for Applied ResearchPublic Health ResearchTwitterFacebookLinkedInEmailHome >> Journals >> Health Technology Assessment >> Volume 27 >> Issue 5ToolkitDownload report PDFDownload report documentsDisclosure of interestDownload report XMLPrintResponses to this report (0)Permissions informationVIEW PROJECTTotal anklereplacement versus ankle arthrodesis for patients aged 50 85 years with end-stage ankle
A Comparison of Wound Related Complications Between Intramedullary and Lateral Plate Osteosynthesis After Fibula Osteotomy in the Lateral Approach Total AnkleReplacement. Total anklereplacement (TAR) has evolved in the last decade from a procedure rife with complication and failure to a promising alternative to arthrodesis. The ability to maintain ankle joint range of motion is showing great
Reliability and validity of the Forgotten Joint Score-12 for total anklereplacement and ankle arthrodesis. This study evaluated the reliability and validity of the Forgotten Joint Score-12 (FJS-12)-a measure of patients' ability to forget their joints in daily life-in patients who underwent total anklereplacement (TAR) or ankle arthrodesis (AA). Patients who underwent TAR or AA were recruited
Influence of sidewall retention and interference fit in total anklereplacement on implant-bone micromotion: A finite element study. The success of uncemented total anklereplacement (TAR) is linked to initial stability because bony ingrowth depends upon limited early micromotion. Tibial implant design fixation features resist micromotion aided by bony sidewall retention and interference fit. Our
Cost-Utility Analysis of Total AnkleReplacement Compared with Ankle Arthrodesis for Patients Aged 50-85 Years with End-Stage Ankle Osteoarthritis: The TARVA Study. Patients with end-stage ankle osteoarthritis suffer from reduced mobility and quality of life and the main surgical treatments are total anklereplacement (TAR) and ankle fusion (AF). Our aim was to calculate the mean incremental
Implant Choice May Reduce the Risk of Early Mechanical Failure in Total AnkleReplacement. Total anklereplacements (TARs) have rapidly advanced in terms of volume, technique, design, and indications. However, TARs are still at risk for early mechanical failure and revision. Prior studies have investigated potential risk factors for failure, but have been limited to smaller series or older
Custom Patient-Specific 3D-Printed Titanium Truss Tibiotalocalcaneal Arthrodesis Implants for Failed Total AnkleReplacements: Classification, Technical Tips, and Treatment Algorithm. The management of failed total anklereplacements, with significant loss of bone stock, is challenging with high rates of complications and associated morbidity. Recent technological advances have enabled the development of patient-customized 3D-printed titanium truss arthrodesis implants, which offer an alternative salvage option for failed total anklereplacements. A prospective observational study was performed of 6 cases of failed total anklereplacements that were managed using custom patient-specific 3D-printed titanium truss arthrodesis implants. Technical tips, classification, and a treatment algorithm
Lessons From Revision Total AnkleReplacement: Tibias Fail Earlier, and Taluses Fail Later (and Fail Again). The literature on survivorship and outcomes after revision total anklereplacement (TAR) in the modern era is limited. This study aimed to describe the timing to revision and survivorship after revision TAR. We hypothesized that tibial-sided failures would occur earlier after the primary
Defining the Patient Acceptable Symptom State (PASS) for PROMIS After Total AnkleReplacement. Although patient-reported outcomes (PROs), such as the Patient-Reported Outcomes Measurement Information System (PROMIS), are a key element of evaluating success after total anklereplacement (TAR), many do not explicitly state a key factor of postoperative success: is the patient satisfied
Outcome after total anklereplacement or ankle arthrodesis in end-stage ankle osteoarthritis on the basis of german-wide data: a retrospective comparative study over 10 years. In symptomatic end-stage osteoarthritis of the ankle joint, total anklereplacement and ankle arthrodesis are the two primary surgical options for patients for whom conservative treatment fails. Published revision rates to undergo an unplanned reoperation within ten years. After total anklereplacement, the unplanned reoperation rate was 38% [95% CI, 29-48%] among 172 patients. For initial surgeries conducted at a later date, unplanned reoperation rates within five years were 21% [95% CI, 19-24%] for 1,168 ankle arthrodesis patients and 23% [95% CI, 19-28%] for 561 total anklereplacement patients. Significant risk
Postoperative Medial Malleolar Fractures in Total AnkleReplacement Are Associated With Decreased Medial Malleolar Width and Varus Malalignment: A Case-Control Study. There are limited data regarding risk factors associated with periprosthetic medial malleolar fractures in total ankle arthroplasty (TAA). This case-control study aimed to identify the risk factors and analyze the effect
Influence of Tibial Component Design Features and Interference Fit on Implant-Bone Micromotion in Total AnkleReplacement: A Finite Element Study. Implant survivorship in uncemented total anklereplacement (TAR) is dependent on achieving initial stability. This is because early micromotion between the implant and bone can disrupt the process of osseointegration, leading to poor long-term
Outcomes of Total AnkleReplacement Versus Ankle Arthrodesis for the Treatment of End-Stage Ankle Arthritis: A Concise Follow-up, at a Minimum of 10 Years, of a Previous Report. Despite the increasing utilization of total anklereplacement (TAR) for end-stage ankle arthritis, there remains a paucity of long-term follow-up data comparing arthroplasty to arthrodesis. The aim of the current paper
Total AnkleReplacement Versus Arthrodesis for End-Stage Ankle Osteoarthritis : A Randomized Controlled Trial. End-stage ankle osteoarthritis causes severe pain and disability. There are no randomized trials comparing the 2 main surgical treatments: total anklereplacement (TAR) and ankle fusion (AF). To determine which treatment is superior in terms of clinical scores and adverse events nonunion rate for AF was 7%. A post hoc analysis suggested superiority of fixed-bearing TAR over AF (-11.1 [CI, -19.3 to -2.9]). Only 52-week data; pragmatic design creates heterogeneity of implants and surgical techniques. Both TAR and AF improve MOXFQ-W/S and had similar clinical scores and number of harms. Total anklereplacement had greater wound healing complications and nerve injuries, whereas AF
Total anklereplacement versus ankle arthrodesis for patients aged 50-85 years with end-stage ankle osteoarthritis: the TARVA RCT. We aimed to compare the clinical effectiveness, cost-effectiveness and complication rates of total anklereplacement with those of arthrodesis (i.e. ankle fusion) in the treatment of end-stage ankle osteoarthritis. This was a pragmatic, multicentre, parallel-group March 2015 and January 2019, 303 participants were randomised using a minimisation algorithm: 152 to total anklereplacement and 151 to ankle fusion. At 52 weeks, the mean (standard deviation) Manchester-Oxford Foot Questionnaire walking/standing domain score was 31.4 (30.4) in the total anklereplacement arm ( = 136) and 36.8 (30.6) in the ankle fusion arm ( = 140); the adjusted difference
Analysis of Polyethylene-Related Revisions After Total AnkleReplacements Reported in US Food and Drug Administration Medical Device Adverse Event Database. There are 2 general types of total anklereplacement (TAR) designs with respect to the polyethylene insert, mobile-bearing (MB) and fixed-bearing (FB) TARs. The aim of this study is to compare polyethylene-related adverse events (AEs as compared with FB TAR designs. Further study of device-related complications with more recent designs for both MB and FB anklereplacement components are needed to improve the outcomes of total anklereplacement. Level III, retrospective comparative study.
Risk Factors for Failure of Total AnkleReplacements: A Data Linkage Study Using the National Joint Registry and NHS Digital. Despite the increasing numbers of anklereplacements, there remains debate about which patients should undergo an anklereplacement, and there are limited studies analyzing risk factors for failure of an anklereplacement. The primary aim of this study is to analyze the risk factors for failure of total anklereplacements. A data linkage study combining the National Joint Registry (NJR) Data and NHS (National Health Service) Digital data was performed. The primary outcome of failure is defined as the removal or exchange of any components of the implanted device. Kaplan-Meier survival charts were used to illustrate survivorship. Multivariable Cox proportional hazards
Outcomes in AnkleReplacement Study (OARS). The aim of this study was to capture 12-month outcomes from a representative multicentre cohort of patients undergoing total ankle arthroplasty (TAA), describe the pattern of patient-reported outcome measures (PROMs) at 12 months, and identify predictors of these outcome measures. Patients listed for a primary TAA at 19 NHS hospitals between February
Early outcomes of the Exactech Vantage fixed-bearing total anklereplacement. The Vantage Total Ankle System is a fourth-generation low-profile fixed-bearing implant that has been available since 2016. We aimed to describe our early experience with this implant. This is a single-centre retrospective review of patients who underwent primary total ankle arthroplasty (TAA) with a Vantage implant
Randomized Controlled Trial Comparing Early Mobilization vs Six Weeks of Immobilization in a Walking Cast Following Total AnkleReplacement. Rehabilitation for patients after total anklereplacement traditionally involves weeks of immobilization in a plaster cast followed by progressive mobilization. In a small randomized trial, we compared teh outcomes of patients who received a 3-component