"Anomaly scan"

Incorporation of vasa previa screening into a routine anomaly scan: A single center cohort study. Vasa previa (VP), defined as unprotected fetal vessels traversing the membranes over the cervix, is associated with a high perinatal mortality when undiagnosed prenatally. Conversely, prenatal diagnosis with ultrasound and cesarean delivery before the membranes rupture is associated with excellent outcomes. However, controversy exists regarding screening for VP. In the UK, routine screening for VP is not recommended. The objective of this study was to report the incidence of VP and our experience in the detection of VP with a universal screening protocol at the time of the second-trimester fetal anomaly scan with third-trimester confirmation in an unselected population of pregnancies. We performed

Introduction of a nationwide first-trimester anomaly scan in the Dutch national screening program. A significant proportion of major fetal structural anomalies can be detected in the first trimester by ultrasound examination. However, the test performance of the first-trimester anomaly scan (FTAS) performed in a low-risk population as part of a nationwide prenatal screening program is unknown

Informed choice and routinization of the second-trimester anomaly scan: a national cohort study in the Netherlands. Since 2007 all pregnant women in the Netherlands are offered the second-trimester anomaly scan (SAS) in a nationwide prenatal screening program. This study aims to assess the level of informed choice of women opting for the SAS and to evaluate the presence of routinization 16 years

First trimester anomaly scan using virtual reality (VR FETUS study): study protocol for a randomized clinical trial. In recent years it has become clear that fetal anomalies can already be detected at the end of the first trimester of pregnancy by two-dimensional (2D) ultrasound. This is why increasingly in developed countries the first trimester anomaly scan is being offered as part of standard

The added value of detailed early anomaly scan in fetuses with increased nuchal translucency. This study aims to assess the utility of a detailed early fetal anatomy scan prior to karyotyping in the management of pregnancies with an increased nuchal translucency (NT). The study included fetuses with NT above the 99th centile. These women were offered the option of an early detailed fetal anatomy

First-trimester screening for trisomy 18, 13, triploidy and Turner syndrome by a detailed early anomaly scan. To examine the performance of first-trimester ultrasound screening for trisomies 18 and 13, triploidy and Turner syndrome based on fetal nuchal translucency thickness (NT), additional fetal ultrasound markers including anatomy of the nasal bone (NB), blood flow across the tricuspid valve (TV) and through the ductus venosus (DV) and a detailed fetal anomaly scan at 11-13 weeks' gestation. This was a retrospective case-matched study involving pregnant women at 11-13 weeks' gestation. The study population consisted of fetuses with trisomy 18, trisomy 13, triploidy or Turner syndrome. For each fetus with an abnormal karyotype, 50 randomly selected euploid fetuses were added to the study

Prevalence of defined ultrasound findings of unknown significance at the second trimester fetal anomaly scan and their association with adverse pregnancy outcomes: the Welsh Study of Mothers and Babies population-based cohort. The aim of this article was to estimate the population prevalence of seven defined ultrasound findings of uncertain significance ('markers') in the second trimester and the associated risk of adverse pregnancy outcomes. A prospective record-linked cohort study of 30 078 pregnant women who had second trimester anomaly scans between July 2008 and March 2011 in Wales was conducted. The prevalence of markers ranged from 43.7 per 1000 singleton pregnancies for cardiac echogenic foci [95% confidence interval (CI): 38.8, 51.1] to 0.6 for mild-to-moderate ventriculomegaly (95% CI

False positive morphologic diagnoses at the anomaly scan: marginal or real problem, a population-based cohort study. Congenital malformations occur in 3-4% of live births. Their prenatal detection is performed by ultrasound screening. Any announcement about a suspected malformation is a source of stress for the parents, and misdiagnosis during ultrasound screening can lead to expensive

Increased nuchal translucency with normal karyotype and anomaly scan: what next? Over the years, it has become clear that increased nuchal translucency is a marker for chromosomal abnormalities, and it is also associated with a wide spectrum of structural anomalies, genetic syndromes, a higher risk of miscarriage, and intrauterine fetal death. These risks are all proportionally related

Comparative Study of Learning Curve for First Trimester Fetal Anomaly Scan Ultrasound scans during first trimester are more difficult than routine mid-trimester ultrasound scans. Practice guidelines for first trimester fetal ultrasound scans have been provided by the International Society of Ultrasound in Obstetrics and Gynecology (ISUOG) since 2013. Using this guidelines, different levels

Influences of the introduction of the 20 weeks fetal anomaly scan on prenatal diagnosis and management of fetal facial clefts. To investigate trends in prenatal diagnosis and termination of pregnancy rates in cases of fetal cleft lip with or without cleft palate (CL ± P), before and after the introduction in The Netherlands of the 20-week anomaly scan in 2007, and to assess the accuracy of this scan for the diagnosis of facial clefts. This was a retrospective cohort study of consecutive cases of CL ± P diagnosed in 2001-2010 in the referral region of the Academic Medical Centre. Cases diagnosed prenatally were identified from the hospital's database. These data, grouped according to the periods before and after the introduction of the routine 20-week anomaly scan, were compared with data

Awareness, Expectations, and Perception of Anomaly Scan Among Mexican Pregnant Women To describe the knowledge, expectations, and perception of women towards the mid-trimester ultrasound scan to detect fetal anomalies in a Mexican population. A cross-sectional survey was conducted in two prenatal diagnostic centers located in Monterrey, Nuevo León, México. One was a university prenatal diagnostic was on expectations before the scan while the third dealt on women´s perception of the fetus during the ultrasound examination. All women attending for a mid-trimester anomaly scan were invited to fill out the first two parts of a pretested structured questionnaire before the scan and after the ultrasound examination, the third part of the questionnaire concerning their experience of the scan session was completed

or pelvicalyceal dilatation of the kidney(s) diagnosed prior to delivery. The estimated incidence is approximately 0.5 to 1%.1 It is usually diagnosed on routine antenatal ultrasound scanning and is normally most frequently identified at the time of the routine mid trimester anomaly scan performed at 20 weeks. However, the normal appearance of one or both renal pelves at the routine anomaly scan does

post mortem unlike any other investigative procedure. The report authors have held the narrative of parents’ vulnerabilities and wishes at the heart of the discussions involved in producing these guidelines. This guideline has been created to assist the perinatal pathologist undertaking autopsies in cases of antepartum intrauterine death (stillbirth) of babies after a normal anomaly scan (i.e. ≥20 maintain an open mind as to the most appropriate investigations as the autopsy proceeds. This guideline applies to autopsies which are carried out after fetal loss following a normal second trimester anomaly scan.5 This statement needs to be treated with a degree of caution; it is always the pathologist’s discretion to determine the extent of examination that is required in the given case, within

may occur prior to, or after, the anomaly (mid-trimester) scan. The approach to the autopsy differs depending on whether this has occurred and the result of the scan. a) If the pregnancy loss occurs before the mid-trimester anomaly scan, or the scan could not be completed for any reason, full post-mortem examination is recommended to check the anatomical structures, where consent has been provided for congenital anomaly’ should be followed. d) If pregnancy loss occurred after a negative anomaly scan, and the baby proves to be non-dysmorphic at external examination, yield from an invasive post-mortem examination is likely to be low.7 As such, in this situation, the pathologist may decide to proceed with an external examination, X-ray and examination of the placenta and omit internal examination

a first-trimester scan, a second-trimester anomaly scan and scans every 4weeksthereafter. Complicated dichorionic twins should bescanned more frequently, depending on the conditionand its severity (GOOD PRACTICE POINT).•Uncomplicated monochorionic twins should have afirst-trimester scan and be scanned every 2 weeks after16weeks, in order to detect TTTS in a timely manner.Complicated monochorionic twins % for a FPR of 5%)72(EVIDENCELEVEL: 2++).Ultrasound screening for structural abnormalitiesin twin pregnancy•Twin fetuses should be assessed for the presence ofany major anomalies at the first-trimester scan, anda routine second-trimester (anomaly) scan should beperformed at around 20 (18–22) weeks’ gestation(GOOD PRACTICE POINT).•Fetal cardiac assessment should be performed inmonochorionic twins

Antenatal palliative care Sadia and Ali attend for their 20-week anomaly scan and are told that their baby is small and has multiple congenital anomalies including complex congenital heart disease. The picture is suggestive of an underlying chromosomal or genetic diagnosis. Sadia and Ali are committed to continuing the pregnancy and decline invasive antenatal testing. They are referred to fetal cardiology

recentadvances.The potential benefits of diagnosing in the thirdtrimester a fetal abnormality not identified at thesecond-trimester anomaly scan include the opportunityto: arrange for the birth to take place in a centerthat can provide the appropriate level of neonatal care;allow the parents time and counseling to prepare forthe birth of a child with an anomaly

, particularly for early infection, and theroutine fetal anomaly scan shows evidence of possiblecongenital syphilis infection, maternal referral to the localfetal medicine centre is recommended. Fetal congenitalsyphilis infection may be suggested by ultrasound scandetection of non-immune hydrops or hepatosplenomegaly.Fetal assessment will help in the planning of antepartumcare as well as neonatal