Branchialcleftcyst and branchialcleftcyst carcinoma, or cystic lymph node and cystic nodal metastasis? Lateral cervical cysts are usually considered as of branchial cleft origin, despite many studies showing that branchial cysts do not arise from the remnants of the branchial apparatus. In the same way, some authors still consider that a true clinicopathological entity such as 'branchial ring could be applicable for both diagnoses. Terms such as 'branchialcleftcyst' and 'branchialcleftcyst carcinoma' are confusing and misleading, and it is questionable as to whether their usage is still tenable.
Age-related outcomes after pediatric branchialcleftcyst excision via NSQIP-P. Branchialcleftcysts present at varying ages; sometimes excision is delayed because of concern about operating in small children. Our goal was to determine if outcomes and complications differed among pediatric age groups. Retrospective, cross-sectional. American College of Surgeons' National Surgical Quality Improvement Pediatric database. Patients who underwent a branchialcleftcyst excision between 2016 and 2020 were identified in the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) Pediatric database. Patients with CPT code 42,815: 'excision branchialcleftcyst, vestige, or fistula, extending beneath subcutaneous tissues and/or into the pharynx' as their primary
A cross-sectional evaluation of outcomes of pediatric branchialcleftcyst excision. To examine complications following pediatric branchialcleftcyst excision by surgical specialty, demographics, and comorbid conditions. A retrospective review of the National Surgical Quality Improvement Program database was performed. Pediatric cases from January 1, 2015 through May 1, 2017 with a current procedural terminology code of 42810 (excision branchialcleftcyst or vestige, confined to skin and subcutaneous tissues) or 42815 (excision branchialcleftcyst, vestige, or fistula, extending beneath subcutaneous tissues and/or into the pharynx) were included. Statistical analysis was performed to assess associations between complications and surgical specialty, demographics, and comorbidities
Solitary cystic metastatic lymph node of occult human papillomavirus-related oropharyngeal cancer mimicking second branchialcleftcyst: A case report. Human papillomavirus (HPV)-related oropharyngeal cancer is becoming more common, the primary cancer AQ4 usually occult and appearing only as cystic cervical lymph node (LN) metastasis. Distinguishing between a benign cystic lesion and cystic LN metastasis is challenging given their similar radiologic and histologic appearances. A 54-year-old man presented with a bulging cystic mass measuring 6.4cm on the right side of neck. Postexcision diagnosis was second branchialcleftcyst. After 2 years, the cystic mass recurred, and HPV-related tonsillar squamous cell carcinoma with cystic metastatic LNs was confirmed after wide tonsillectomy and neck
Detection of human papillomavirus in branchialcleftcysts High-risk human papillomavirus (HPV) DNA has been reported to be present in branchialcleftcysts, but further information is required to clarify the role of HPV infection in branchialcleftcysts. The presence of HPV, the viral load and the physical statuses in samples from six patients with branchialcleftcysts were investigated using the polymerase chain reaction (PCR), quantitative PCR, hybridization (ISH) using HPV DNA probes and p16 immunohistochemical analysis. High-risk type HPV-16 DNA was identified in four of the six branchialcleftcysts analyzed. Of the HPV-positive branchialcleftcysts, three exhibited mixed-type integration of HPV. HPV DNA was distributed among the basal-to-granular layers of the cystic wall in ISH analysis
A unique location of branchialcleftcyst: case report and review of the literature. Branchialcleftcysts (BCC) are benign lesions caused by anomalous development of the branchial apparatus. This case report describes a 63-year-old woman with a 12 cm×12cm sized cystic mass located anterior to the manubrium sternum and sternum. MRI revealed a cystic lesion with a sinus tracking to the piriform sinus. Postoperative histopathological examination confirmed the diagnosis of branchialcleftcyst. Because of the course of the sinus track, it is believed that this was a fourth branchialcleftcyst. These are the rarest of the branchial anomalies, and extension below the peri-thyroid region is very infrequently described. When this extension occurs, it is always post-sternal into the mediastinum
Unusually rapid development of a lateral neck mass: Diagnosis and treatment of a branchialcleftcyst. A case report Branchialcleftcysts are benign lesions caused by anomalous development of the branchial cleft. Cases that arise in the lateral neck region are often misdiagnosed, resulting initially in inappropriate management. We describe a 32-year-old woman with a swelling on the right side
Possible Estrogen Dependency in the Pathogenesis of BranchialCleftCysts Even though branchialcleftcysts are currently accepted as a congenital anomaly, there is often a long delay until clinical presentation; branchialcleftcysts classically appear in the second to fourth decade of life. Our observation of their occurrence in three pregnant women encouraged us to contemplate a possible hormonal influence. Immunohistological analysis was performed for the evaluation of the estrogen receptor alpha (ER) in paraffin-embedded tissue specimens of 16 patients with a diagnosis of branchialcleftcyst, with three of them being pregnant. Expression of ER was detected within epithelial cells only in branchialcleftcysts in pregnant females; moreover, higher growth fractions (Ki-67/Mib1) were
Nasopharyngeal Carcinoma with Cystic Cervical Metastasis Masquerading as BranchialCleftCyst: A Potential Pitfall in Diagnosis and Management Most metastatic lymph nodes from head and neck malignancy are solid. Cystic nodes are found in 33% - 61% of carcinomas arise from Waldeyer's ring, of which only 1.8% - 8% originate are from the nasopharynx. Some cystic cervical metastases were initially presumed to be branchialcleftcyst. This case report aims to highlight the unusual presentation of cystic cervical metastasis secondary to nasopharyngeal carcinoma in a young adult. The histopathology, radiological features and management strategy were discussed. A 36-year-old man presented with a solitary cystic cervical swelling, initially diagnosed as branchialcleftcyst. Fine needle aspiration
Fine needle aspiration cytology versus frozen section in branchialcleftcysts. Branchialcleftcysts occur because of a failure of involution of the second branchial cleft. However, as well-differentiated squamous cell carcinoma can mimic branchialcleftcysts, there is a lack of consensus on the appropriate management of cystic neck lumps. To report our experience of fine needle aspiration cytology and frozen section examination in the management of cystic neck lumps. Retrospective case note review of patients managed in the Southern General Hospital, Scotland, UK. The sensitivity of fine needle aspiration cytology and frozen section for detecting branchialcleftcysts was 75 per cent and 100 per cent respectively. Two patients who did not undergo intra-operative frozen section examination
Case report of a p16INK4A-positive branchialcleftcyst. To report the occurrence of a concurrent oropharyngeal papilloma and branchialcleftcyst linked by p16(INK4A) and human papillomavirus immunohistochemistry. A 42-year-old woman presented with a 1-month history of a left lateral neck mass. Contrast enhanced computed tomography showed a hypodense lesion 20 mm in diameter anteromedial to the left sternocleidomastoid muscle. Ultrasound-guided fine needle aspiration suggested a branchialcleftcyst. Panendoscopy was performed at the time of neck mass removal, and a papillomatous lesion was removed from the left hypopharynx. Histopathological analysis showed the neck lesion to be a branchial cyst containing lymphoid tissue, and the oral lesion to be a squamous papilloma. Immunohistochemical
Endoscope-assisted approach to excision of branchialcleftcysts. The purpose of this study is to describe an endoscope-assisted surgical technique for the excision of branchialcleftcysts and compare it to the standard approach. Retrospective case series review. Twenty-seven cases described as branchial cleft excisions performed by a single surgeon at one academic medical center were ± 0.23) was significantly less than that of the standard approach (mean = 4.10 ± 1.46, P = 0.008) despite the fact that there was no significant difference in cyst size between the two groups (P = 0.09). The other variables examined, including operative time and surgical outcomes, were not significantly different between the two groups. This transcervical endoscope-assisted approach to branchialcleft
Endoscope-assisted second branchialcleftcyst resection via an incision along skin line on lateral neck. The aim of the study is to report the feasibility of endoscope-assisted second branchialcleftcyst resection via a small incision along the skin line on the lateral neck. In total, 41 patients from the Department of Otolaryngology, Foshan Hospital of Yat-sen University were randomly assigned to conventional (20 patients) or endoscope-assisted (21 patients) second branchialcleftcyst resection. The patient clinical characteristics, operation time, operative bleeding volume, postoperative complications, and subjective satisfaction with the incision scar (measured using a visual analog scale) were compared between the groups. All 41 s branchialcleftcyst resections were successfully performed