"Bronchial challenge test"

Anticipating undiagnosed asthma in symptomatic adults with normal pre- and post-bronchodilator spirometry: a decision tool for bronchial challenge testing. Some patients with asthma demonstrate normal spirometry and remain undiagnosed without further testing. To determine clinical predictors of asthma in symptomatic adults with normal spirometry, and to generate a tool to help clinicians decide who should undergo bronchial challenge testing (BCT). Using random-digit dialling and population-based case-finding, we recruited adults from the community with respiratory symptoms and no previous history of diagnosed lung disease. Participants with normal pre- and post-bronchodilator spirometry subsequently underwent BCT. Asthma was diagnosed in those with symptoms and a methacholine provocative

ERS Technical Standard on Bronchial Challenge Testing: Pathophysiology and Methodology of Indirect Airway Challenge Testing. Recently, this international task force reported the general considerations for bronchial challenge testing and the performance of the methacholine challenge test, a "direct" airway challenge test. Here, the task force provides an updated description of the pathophysiology

ERS technical standard on bronchial challenge testing: general considerations and performance of methacholine challenge tests. This international task force report updates general considerations for bronchial challenge testing and the performance of the methacholine challenge test. There are notable changes from prior recommendations in order to accommodate newer delivery devices. Rather than

Research on the Application of Electrical Impedance Tomography in Bronchial Challenge Testing The purpose of this study was to examine whether electrical impedance tomography (EIT) was capable of identifying the deteriorated lung function on a regional level during bronchial challenge testing and whether EIT may provide additional information during bronchial challenge testing and identify

Changes in PH in exhaled breath condensate after specific bronchial challenge test in patients with chronic hypersensitivity pneumonitis: a prospective study. The aim of this study was to investigate the influence of the specific inhalation challenge (SIC) on changes of pH values in exhaled breath condensate (EBC) in patients with hypersensitivity pneumonitis (HP). A prospective study of 85

Accuracy of bronchial challenge testing in response to exercise in diagnosis of asthma PROSPEROInternational prospective register of systematic reviews Print | PDFAccuracy of bronchial challenge testing in response to exercise in diagnosis of asthmaBernard Higgins, Sharon Swain, Qudsia Malik, Toby Sands, Alfredo Mariani, Lina Gulhane, Stephen Deed, Melina Vasileiou, Amy CrispCitationBernard Higgins, Sharon Swain, Qudsia Malik, Toby Sands, Alfredo Mariani, Lina Gulhane, Stephen Deed, Melina Vasileiou, Amy Crisp. Accuracy of bronchial challenge testing in response to exercise in diagnosis of asthma. PROSPERO 2023 CRD42023438844 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023438844Review questionIn people under investigation for asthma, what

Accuracy of bronchial challenge testing with histamine and methacholine in the diagnosis of asthma PROSPEROInternational prospective register of systematic reviews Print | PDFAccuracy of bronchial challenge testing with histamine and methacholine in the diagnosis of asthmaBernard Higgins, Sharon Swain, Qudsia Malik, Toby Sands, Alfredo Mariani, Stephen Deed, Lina Gulhane, Amy Crisp, Melina VasileiouCitationBernard Higgins, Sharon Swain, Qudsia Malik, Toby Sands, Alfredo Mariani, Stephen Deed, Lina Gulhane, Amy Crisp, Melina Vasileiou. Accuracy of bronchial challenge testing with histamine and methacholine in the diagnosis of asthma. PROSPERO 2023 CRD42023438302 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023438302Review questionIn people under investigation for asthma

Accuracy of bronchial challenge testing with mannitol for diagnosis of asthma PROSPEROInternational prospective register of systematic reviews Print | PDFAccuracy of bronchial challenge testing with mannitol for diagnosis of asthmaBernard Higgins, Sharon Swain, Qudsia Malik, Toby Sands, Alfredo Mariani, Stephen Deed, Lina Gulhane, Amy Crisp, Melina VasileiouCitationBernard Higgins, Sharon Swain , Qudsia Malik, Toby Sands, Alfredo Mariani, Stephen Deed, Lina Gulhane, Amy Crisp, Melina Vasileiou. Accuracy of bronchial challenge testing with mannitol for diagnosis of asthma. PROSPERO 2023 CRD42023438827 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023438827Review questionIn people under investigation for asthma, what is the diagnostic test accuracy and cost

Airways resistance in bronchial challenge testing. Measurement of airways resistance is an alternative to spirometry to assess airflow obstruction. This can be measured by the interrupter technique (RInt) using a handheld device. We wished to know how RInt compared to forced expiratory volume in 1 s (FEV1) during a histamine challenge test. Twenty-nine (13 male) patients, aged 48.9 (SD 15.3

Diagnostic properties of the methacholine and mannitol bronchial challenge tests: a comparison study. Airway hyperresponsiveness is a common feature of asthma. Methacholine and mannitol are two representative agonists for bronchial challenge. They have theoretically different mechanisms of action, and may have different diagnostic properties. However, their difference has not been directly

Cold air bronchial challenge test as diagnostic tool for asthma and exercise-induced bronchoconstriction: a systematic review Cold air bronchial challenge test as diagnostic tool for asthma and exercise-induced bronchoconstriction: a systematic review Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith

by eosinophil count, FeNO, BDR or PEF variability but still suspected on clinical grounds, refer for consideration of a bronchial challenge test. Diagnose asthma if bronchial hyper-responsiveness is present. [BTS/NICE/SIGN 2024] Children aged 5 to 16 See also algorithm B for a summary of objective tests for diagnosing asthma in children aged 5 to 16 with a history suggesting asthma. 1.2.5 Measure the FeNO is more than 0.5 x 109 per litre. [BTS/NICE/SIGN 2024] 1.2.9 If there is still doubt about the diagnosis, refer to a paediatric specialist for a second opinion, including consideration of a bronchial challenge test. [BTS/NICE/SIGN 2024] Asthma: diagnosis, monitoring and chronic asthma management (BTS, NICE, SIGN)(NG245)© NICE 2024. All rights reserved. Subject to Notice of rights ( 12 of64 For a short

. * Diagnose asthma if PEF variability (amplitude percentage mean) is 20% or more. * If asthma is not confirmed by eosinophil count, FeNO, BDR, or PEF variability but is still suspected clinically, consider an alternative diagnosis and arrange specialist referral for consideration of a bronchial challenge test (asthma is diagnosed if bronchial hyper-responsiveness is present). * See the BTS, NICE, and SIGN , consider an alternative diagnosis and arrange paediatric referral for a specialist assessment, including consideration of a bronchial challenge test. * See the BTS, NICE, and SIGN (2024) summary Algorithm B: Objective tests for diagnosing asthma in children aged 5 to 16 years with a history suggesting asthma for more information. * In children under 5 years of age, be aware that making an asthma

is not confirmed by objective testing but is still suspected clinically in adults and children, referral should be arranged for consideration of a bronchial challenge test (asthma is diagnosed if bronchial hyper-responsiveness is present). * The recommendation to refer directly to a specialist occupational lung disease service if there is suspected occupational asthma is based on the BTS publication

2020, Vol 133 No 1517ISSN 1175-8716 © NZMAwww.nzma.org.nz/journal• Alternative methods to identify variable airflow obstruction include repeat measures of spirometry with bronchodilator reversibility, peak flow variability with repeat measures at different times of the day, and other specialist tests such as measures of bronchial challenge testing. Once the diagnosis has been

hyperreactivity measures Direct bronchial challenge test with histamine or methacholine Direct bronchial challenge test with histamine or methacholine In November 2017, the use of histamine and methacholine described in recommendations 1.3.11 and 1.3.12 was off label. See NICE's information on prescribing medicines. 1.3.11 Offer a direct bronchial challenge test with histamine or methacholine to adults (aged 17 and over) if there is diagnostic uncertainty after a normal spirometry and either a: • FeNO level of 40 ppb or more and no variability in peak flow readings or or • FeNO level of 39 ppb or less with variability in peak flow readings. Regard a PC20 value of 8 mg/ml or less as a positive test. [2017] [2017] 1.3.12 Consider a direct bronchial challenge test with histamine or methacholine in adults (aged 17