"CSF glucose"

Pleocytosis is not fully responsible for low CSF glucose in meningitis The mechanism of hypoglycorrhachia-low CSF glucose-in meningitis remains unknown. We sought to evaluate the relative contribution of CSF inflammation vs microorganisms (bacteria and fungi) in lowering CSF glucose levels. We retrospectively categorized CSF profiles into microbial and aseptic meningitis and analyzed CSF leukocyte count, glucose, and protein concentrations. We assessed the relationship between these markers using multivariate and stratified linear regression analysis for initial and repeated CSF sampling. We also calculated the receiver operating characteristics of CSF glucose and CSF-to-serum glucose ratios to presumptively diagnose microbial meningitis. We found that increasing levels of CSF

CSF Glucose CSF Glucose * Versions * Standard Desktop * Legacy Desktop * Mobile Web * Iphone/Ipad App * * Help Toggle navigation * * Home * Books: A to N * Cardiovascular Medicine * Dentistry * Dermatology * Emergency Medicine * Endocrinology * Gastroenterology * Geriatric Medicine * Gynecology to Palliative Care * * Administration * Patient Satisfaction * Documentation 4 * * advertisement * Home * Neurology Book * Pathology and Laboratory Medicine Chapter * CSF Glucose CSF Glucose Aka: CSF Glucose, Cerebrospinal Fluid Glucose, Hypoglycorrhachia Neurology Pathology and Laboratory Medicine Chapter * Cerebrospinal Fluid

Pearls & Oy-sters: Chronic mumps meningoencephalitis with low CSF glucose and acute hydrocephalus in an adult. Chronic lymphocytic meningoencephalitis with low glucose and increased adenosine deaminase (ADA) levels in the CSF together with hydrocephalus represents a diagnostic challenge of varied etiology and only seldom is due to a viral (mumps) infection.

CSF Glucose CSF Glucose * Versions * Standard Desktop * Legacy Desktop * Mobile Web * Iphone/Ipad App * * Help Toggle navigation * * Home * Books: A to N * Cardiovascular Medicine * Dentistry * Dermatology * Emergency Medicine * Endocrinology * Gastroenterology * Geriatric Medicine * Gynecology to Palliative Care * * Administration * Patient Satisfaction * Documentation 4 * * advertisement * Home * Neurology Book * Pathology and Laboratory Medicine Chapter * CSF Glucose CSF Glucose Aka: CSF Glucose, Cerebrospinal Fluid Glucose, Hypoglycorrhachia Neurology Pathology and Laboratory Medicine Chapter * Cerebrospinal Fluid

Child Neurology: Differential diagnosis of a low CSF glucose in children and young adults. Analysis of CSF is daily routine in patients with acute neurologic disorders like CNS infections. In those patients, the finding of a low CSF glucose may influence further diagnostic workup and therapeutic choices. The interpretation of a low CSF glucose in patients with a chronic neurologic disorder , however, is a less common practice. We present a practical overview on the differential diagnosis of a low CSF glucose and stress the importance of recognizing a low CSF glucose as the diagnostic marker for GLUT1 deficiency syndrome, a treatable neurometabolic disorder.

protein levels, and decreased CSF glucose levels. Imaging findings more common in GFAP-IgG than in AQP4-IgG myelitis were longer diseased segments, central canal enhancement, and gadolinium-enhancing brain lesions. Higher EDSS scores at discharge distinguished GFAP-IgG from MOG-IgG. Clinical, laboratory, imaging, and outcome variables facilitate differential diagnosis of myelitis subtypes.

administered intranasally) or I-40 group (n = 42, 1ml 40U/ml insulin administered intranasally). POD incidence within postoperative days 1-3 was recorded. Fingertip blood glucose levels were recorded 40 min after insulin or saline administration the day before surgery, operating room entry and immediately after the procedure. Cerebrospinal fluid (CSF) glucose and lactate levels were also measured. Compared with the Control group, the I-20 and I-40 groups showed significantly lower POD incidence (39.5% versus 11.4% versus 14.3%, p = 0.002). Furthermore, no significant difference in POD incidence was observed between the I-20 and I-40 groups. CSF glucose levels were significantly higher in the I-40 group than in the Control group (p <0.0167). CSF lactate and fingertip blood glucose levels were not significantly

* coagulation studies * LFTs * C-reactive protein (CRP) * blood culture * cerebrospinal fluid (CSF) Gram stain * CSF culture * CSF cell count and differential * CSF glucose and protein * antigen detection in CSF * Gram stain and culture of other sterile body fluids * chest x-ray * joint x-ray * CT headMore 1st investigations to orderInvestigations to consider * echocardiographyMore investigations

concentration * CSF glucose concentration * CSF microscopy, Gram stain, culture and sensitivities * CSF lactate (adults) * throat swab for cultureFull detailsInvestigations to consider * cranial CT * complement deficiency (children) * serum HIV (adults)Full detailsLog in or subscribe to access all of BMJ Best PracticeTreatment algorithmINITIALsuspected bacterial meningitis: presenting in hospitalsuspected

and differential * cerebrospinal fluid (CSF) protein * cerebrospinal fluid (CSF) glucose * cerebrospinal fluid India ink stain * cerebrospinal fluid (CSF) culture * cerebrospinal fluid cryptococcal polysaccharide antigen test * cerebrospinal fluid Histoplasma antigen * cerebrospinal fluid Histoplasma antibodies * cerebrospinal fluid coccidioidal IgG antibodies * cerebrospinal fluid (CSF) galactomannan antigen

, activated PTT, fibrinogen, fibrin degradation products) * serum HIV * serum procalcitonin (PCT) * serum CRP if PCT not available * cerebrospinal fluid (CSF) protein * CSF lactate * CSF glucose * CSF microscopy, Gram stain, culture, and sensitivities * CSF cell count * CSF polymerase chain reaction (PCR) for pneumococcusFull detailsInvestigations to consider * neuroimaging * CSF PCR for tuberculosis * CSF

PracticeDiagnostic investigations1st investigations to order * blood cultures * FBC and differential * C-reactive protein (CRP) * serum urea, creatinine, and electrolytes * blood gases * blood glucose * CSF microscopy * CSF Gram stain * CSF bacterial culture * CSF protein * CSF glucose * CSF lactate * CSF, stool and throat swab PCR for viral pathogens * HIV serology/HIV reverse transcriptase (RT)-PCRFull

, activated PTT, fibrinogen, fibrin degradation products) * serum HIV * serum procalcitonin (PCT) * serum CRP if PCT not available * cerebrospinal fluid (CSF) protein * CSF lactate * CSF glucose * CSF microscopy, Gram stain, culture, and sensitivities * CSF cell count * CSF polymerase chain reaction (PCR) for pneumococcusFull detailsInvestigations to consider * neuroimaging * CSF PCR for tuberculosis * CSF

concentration * CSF glucose concentration * CSF microscopy, Gram stain, culture and sensitivities * CSF lactate (adults) * throat swab for cultureFull detailsInvestigations to consider * cranial CT * complement deficiency (children) * serum HIV (adults)Full detailsLog in or subscribe to access all of BMJ Best PracticeTreatment algorithmINITIALsuspected bacterial meningitis: presenting in hospitalsuspected

infection: duration of postoperative external drainage (odds ratio [OR] 1.19, P = 0.005), continued fever (OR 2.11, P = 0.036), CSF turbidity (OR 2.73, P = 0.014), CSF pressure (OR 1.01, P = 0.018), CSF total protein level (OR 1.26, P = 0.026), CSF glucose concentration (OR 0.74, P = 0.029), and postoperative serum albumin level (OR 0.84, P < 0.001). Using these variables to construct the final model

puncture was performed, which revealed cloudy cerebrospinal fluid (CSF), with an elevated CSF protein level (78 mg/dL; reference range, 7.0-35.0 mg/dL) and a low CSF glucose level (37 mg/dL [2.05 mmol/L]; reference range, 45-70 mg/dL [2.50-3.89 mmol/L]); otherwise, CSF encephalopathy, an autoimmune panel, and cultures were negative. CT and MRI of the brain with paranasal sinus were performed. Nasal

, and another CBC revealed progressive cytopenia. A bone marrow study showed hypocellularity and active hemophagocytic activity, and intravenous immunoglobulin was additionally given due to the diagnosis of HLH. Cerebrospinal fluid (CSF) analysis showed 60/mm white blood cells (N 55%, L 45%), 141 mg/dL glucose (0.7 blood-CSF glucose ratio), < 4 mg/dL protein; results of Gram stain and bacterial culture were

based on a sustained reduction in cerebrospinal fluid (CSF) glucose levels. Multiple CSF cultures were sterile. We confirmed infection by Ureaplasma species using the melting temperature mapping method. Treatment with erythromycin and ciprofloxacin resulted in a gradual decrease in the bacterial count in the CSF to 0. Our study highlights the potential utility of the melting temperature mapping method