Emergent CarotidStenting During Thrombectomy in Tandem Occlusions Secondary to Dissection: A STOP-CAD Secondary Study. The optimal endovascular management of cervical carotid dissection causing tandem occlusion remains uncertain. We investigated the impact of emergent carotidstenting during endovascular treatment (EVT) for acute ischemic stroke (AIS) in patients with tandem occlusion secondary -1.86, p=0.315) or sICH (7.3% vs 7.9%; aOR OR 0.95, 95% CI 0.41-2.2, p=0.913). Emergent carotidstenting was associated with successful intracranial recanalization (81.8% vs 76.6% aOR 2.62, 95% CI 1.52-4.5, p<0.001). Results did not meaningfully change in additional analyses. In patients presenting with an acute anterior circulation tandem occlusion secondary to cervical carotid artery dissection
Cangrelor for emergent carotidstenting during stroke thrombectomy: a comparative analysis versus glycoprotein IIb/IIIa inhibitors or aspirin monotherapy. Periprocedural antiplatelet treatment is a key determinant for the risk-benefit balance of emergent carotid artery stenting (eCAS) during stroke endovascular treatment (EVT). We aimed to assess the safety and efficacy profile of cangrelor with cangrelor, GPIIb/IIIa inhibitors or aspirin monotherapy. The primary outcome was functional outcome at 90 days, assessed by the modified Rankin Scale (mRS). Secondary outcomes included intracranial recanalization, hemorrhagic transformation and carotidstent patency at day 1. Of the 1687 patients treated, 384 met the inclusion criteria: 91 received cangrelor, 77 received GPIIb/IIIa inhibitors and 216
Mediation Analysis of Acute CarotidStenting in Tandem Lesions: Effect on Functional Outcome in a Multicenter Registry. Current evidence suggests that acute carotid artery stenting (CAS) for cervical lesions is associated with better functional outcomes in patients with acute stroke with tandem lesions (TLs) treated with endovascular therapy (EVT). However, the underlying causal pathophysiologic
The PERFORMANCE II Trial: A Prospective Multicenter Investigation of a Novel CarotidStent System. Several randomized clinical trials have shown that the composite endpoint of death, stroke, and myocardial infarction (MI) is equivalent between carotid artery stenting and carotid endarterectomy. However, the risk of minor stroke has been consistently higher with carotid artery stenting . The authors sought to evaluate the safety and effectiveness of a novel carotidstent system comprised of a stent, an adjustable integrated embolic filter and a postdilation balloon, in patients at elevated risk for adverse events from carotid endarterectomy. PERFORMANCE II (Protection against Emboli during caRotid artery stenting using a 3-in-1 delivery system comprised oF a pOst-dilation balloon
The Elevated Stroke/Death Rates among Asymptomatic Patients Undergoing CarotidStenting in the Pacific Northwest Are Associated with High-Risk Patient Selection. Current guidelines recommend treatment of patients with asymptomatic carotid stenosis when stroke/death rates less than 3% can be achieved. However, in the Pacific Northwest region of the Vascular Quality Initiative (VQI) elevated carotidstenting in the Pacific Northwest from 2016 to 2022, of which 886 (76.8%) underwent TCAR and 268 (23.2%) underwent TF-CAS. The overall stroke/death rates were 2.5% and 3.0% for TCAR and TF-CAS, respectively. Among centers with stroke/death rates above 3%, for both TCAR and TF-CAS, all were in the top half of centers by volume. When patients undergoing TCAR were assessed, those treated at centers
Dual-layered stents reduce cerebral embolism compared with first-generation stents during carotidstenting of high lipid core plaque lesions. Periprocedural lipid core plaque (LCP) has been detected in carotid arteries assessed by catheter-based near-infrared spectroscopy (NIRS). High LCP is associated with cerebral embolism after carotid artery stenting (CAS) using a first-generation stent. We
A propensity score-matched comparative study of balloon guide catheters versus conventional guide catheters for concurrent mechanical thrombectomy with carotidstenting in tandem strokes: comparison of first pass effect, symptomatic intracranial hemorrha Extensive clot burden in tandem strokes accounts for poor mechanical thrombectomy (MT) outcomes. Several studies have shown the benefit
Impact of CarotidStent Design on Embolic Filter Debris Load During Carotid Artery Stenting. The carotidstent design may influence the risk of embolization during carotid artery stenting. The aim of the study was to assess this risk by comparing the quantity of embolized material captured by filters during carotid artery stenting, using different stent designs. We conducted a single-center retrospective study of patients undergoing carotid artery stenting for asymptomatic carotid stenosis >70% (2010-2022) in a tertiary academic hospital (Padua University Hospital, Italy). Carotidstents were classified according to their design as open-cell (OCS), closed-cell (CCS), or micromesh stents (MMS). A distal filter protection was used in all patients, and the amount of captured embolized particles
Young Patients Undergoing CarotidStenting Procedures Have an Increased Rate of Procedural Failure at One Year Follow-Up. The outcomes of patients with premature cerebrovascular disease (age ≤ 55 years) who undergo carotid artery stenting are not well defined. Our study objective was to analyze the outcomes of younger patients undergoing carotidstenting. The SVS VQI was queried for transfemoral the indications for carotidstenting in patients with premature cerebrovascular disease, and those who do undergo stenting may require close follow-up given.
Comparison of three antithrombotic strategies for emergent carotidstenting during stroke thrombectomy: a multicenter study. Periprocedural antithrombotic treatment is a key determinant for the risk-benefit balance of emergent carotid artery stenting (eCAS) during stroke thrombectomy. We aimed to assess the safety and efficacy of three types of antithrombotic treatment. Retrospective review aspirin monotherapy, 38 aspirin+heparin, and 61 an aggressive treatment. Aggressive antiplatelet treatment was associated with an increased rate of excellent (modified Thrombolysis in Cerebral Infarction (mTICI) 2c-3) recanalization and reduced carotidstent thrombosis at day 1 (3.5% vs 16.3%), compared with non-aggressive strategy. There were no significant differences in hemorrhagic transformation
Periprocedural P2Y(12) inhibitors improve perioperative outcomes after carotidstenting by primarily decreasing strokes. The continuation of antiplatelet agents in the periprocedural period around carotidstenting (CAS) procedures is felt to be mandatory to minimize the risk of periprocedural stroke. However, the optimal antiplatelet regimen is unclear, with some advocating dual antiplatelet
Outcomes of carotidstenting in patients with fibromuscular dysplasia. Fibromuscular dysplasia (FMD) is a noninflammatory arterial disease that affects the extracranial carotid arteries in young patients. The ideal treatment of FMD has continued to be debated, and the role of carotid artery stenting (CAS) is controversial. The aim of the present study was to assess the feasibility and outcomes
24-Hour CarotidStent Patency and Outcomes After Endovascular Therapy: A Multicenter Study. Management of extracranial internal carotid artery steno-occlusive lesion during endovascular therapy remains debated. Stent occlusion within 24 hours of endovascular therapy is a frequent event after acute carotid artery stenting, and we currently lack large population results. We investigated
Hemodynamic Instability Predicts In-Hospital and One-Year Mortality After TransCarotid Artery Revascularization and TransFemoral CarotidStenting. Blood pressure fluctuations are a common hemodynamic alteration following carotid artery stenting either with transfemoral (TFCAS) or transcarotid (TCAR) approach and are thought to be related to alteration in baroreceptor function due to angioplasty
Association of Year of Surgery and CarotidStenting Outcomes in High-risk Patients, 2015-2021. This cohort study quantifies the yearly trends and outcomes of transcarotid artery revascularization vs transfemoral carotid artery stenting among high-risk patients from 2015 to 2021.
Long-Term Outcomes of Carotid Endarterectomy vs. Transfemoral CarotidStenting in a Medicare-Matched Database. Carotid endarterectomy is associated with lower risk of perioperative stroke compared to transfemoral carotid artery stenting in the treatment of carotid artery stenosis. However, there is discrepancy in data regarding long-term outcomes. We aimed to compare long-term outcomes
Variation in Carotid Artery Stenosis Measurements Among Facilities Seeking CarotidStenting Facility Accreditation. Based on the inclusion criteria of clinical trials, the degree of cervical carotid artery stenosis is often used as an indication for stent placement in the setting of extracranial carotid atherosclerotic disease. However, the rigor and consistency with which stenosis is measured outside of clinical trials are unclear. In an agreement study using a cross-sectional sample, we compared the percent stenosis as measured by real-world physician operators to that measured by independent expert reviewers. As part of the carotidstenting facility accreditation review, images were obtained from 68 cases of patients who underwent carotidstent placement. Data collected included
SCAI/SVM Expert Consensus Statement on CarotidStenting: Training and Credentialing for CarotidStenting SCAI/SVM Expert Consensus Statement on CarotidStenting: Training and Credentialing for CarotidStenting SCAI/SVM expert consensus statement on CarotidStenting: Training and credentialing for CarotidStenting - Aronow - 2016 - Catheterization and Cardiovascular Interventions - Wiley Online
Unplanned readmission after carotidstenting versus endarterectomy: analysis of the United States Nationwide Readmissions Database. Hospital readmissions are costly and reflect negatively on care delivered. To have a better understanding of unplanned readmissions after carotid revascularization, which might help to prevent them. The Nationwide Readmissions Database was used to determine rates
The role of heparin in preventing the early silent ischemia in carotidstenting. Serebral silent ischemia is a complication of carotidstenting. If silent ischemia occurs 24 h later of carotidstenting, it called early serebral silent ischemia. The aim of this study was to evaluate the effect of heparin infusion on the prevention of early silent ischemia in patients who underwent carotidstenting. We included 26 patients who underwent carotidstenting. Patients who had carotidstenting, we randomized into two groups. The first group of patients were given continuously heparin infusion a maximum of 20,000 units for 24 h, and screened the aPTT value each 6 h. The aPTT value aimed a range of 2-3 times to up baseline. The second group didn't take heparin infusion. Diffusion weighted magnetic