Thoracoscopic surgical ablation versus catheterablation as first-line treatment for long-standing persistent atrial fibrillation: the CASA-AF RCT Thoracoscopic surgical ablation versus catheterablation as first-line treatment for long-standing persistent atrial fibrillation: the CASA-AF RCT * Text only * * Home * Journals * * Other NIHR research * * For authors * For reviewers * About to catheterablation in achieving freedom from atrial arrythmias after a single procedure without anti-arrhythmic drugs. {{author}}{{author}}{{($index < metadata.AuthorsAndEtalArray.length-1) ? ',' : '.'}} Shouvik Haldar, Habib R Khan, Vennela Boyalla, Ines Kralj-Hans, Simon Jones, Joanne Lord, Oluchukwu Onyimadu, Anitha Sathishkumar, Toufan Bahrami, Jonathan Clague, Anthony De Souza, Darrel Francis, Wajid
Clinical commissioning policy: Catheterablation for paroxysmal and persistent atrial fibrillation (adults) Skip to main contentCookies on the NHS England websiteWe’ve put some small files called cookies on your device to make our site work.We’d also like to use analytics cookies. These send information about how our site is used to a service called Google Analytics. We use this information to improve our site.Let us know if this is OK. We’ll use a cookie to save your choice. You can read more about our cookies before you choose. Change my preferences I'm OK with analytics cookiesHome News Publications Statistics Blogs Events Contact usSearch SearchAbout us Our work Commissioning Get involved CoronavirusClinical commissioning policy: Catheterablation for paroxysmal and persistent atrial
The risk of malnutrition as a predictor of arrhythmia recurrence after catheterablation in patients with paroxysmal non-valvular atrial Fibrillation and heart failure with preserved ejection fraction. Malnutrition presents a significant challenge in managing patients with atrial fibrillation (AF) and heart failure with preserved ejection fraction (HFpEF), yet its impact on AF recurrence after catheterablation in this population remains unclear. We conducted a retrospective analysis of 204 patients with paroxysmal non-valvular AF and HFpEF who underwent radiofrequency or cryoballoon ablation. Risk of malnutrition as assessed using three screening tools: the Controlling Nutritional Status (CONUT) score, Prognostic Nutritional Index (PNI), and Nutritional Risk Index (NRI)]. We examined
In previous MI with ventricular tachycardia (VT), catheterablation reduced mortality or VT events more than antiarrhythmic drug therapy at 4 y. GIM/FP/GP: [Formula: see text] Cardiology: [Formula: see text].
Left Ventricular Entry to Reduce Brain Lesions During CatheterAblation: A Randomized Trial Catheterablation of ventricular arrhythmias, one of the most rapidly growing procedures in cardiac electrophysiology, is associated with magnetic resonance imaging-detected brain lesions in more than half of cases. Although a retrograde aortic approach is conventional, modern tools enable entry through with left ventricular arrhythmias undergoing catheterablation procedures were randomly assigned to a transseptal puncture approach compared (1:1) with a retrograde aortic approach. The primary outcome was the presence of an acute brain lesion detected by magnetic resonance imaging. Secondary outcomes included clinically manifest complications, procedural efficacy, and 6-month neurocognitive assessments
Deep neuromuscular blockade during radiofrequency catheterablation under general anesthesia reduces the prevalence of atrial fibrillation recurrence when compared to moderate neuromuscular blockade: A randomized controlled trial. Proper anesthesia management is required to maintain immobilization and stable breathing of the patient to improve catheter contact and stability during catheterablation for PVI. However, it remains unclear whether the depth of neuromuscular blockade affects the results of RFCA under general anesthesia. The patients were randomly assigned to either the moderate neuromuscular blockade group (Group M, train-of-four 1 to 2) or the deep neuromuscular blockade group (Group D, posttetanic count 1-2). The primary outcome was the 12-month AF recurrence rate using
Targeted lung denervation using catheterablation for chronic obstructive pulmonary disease – Addendum to Commission H16-01 1 Translation of the executive summary of addendum H18-02 Gezielte Lungendenervierung durch Katheterablation bei chronisch obstruktiver Lungenerkrankung – Addendum zum Auftrag H16-01 (Version 1.0; Status: 27 April 2018 ). Please note: This document was translated by an external translator and is provided as a service by IQWiG to English-language readers. However, solely the German original text is absolutely authoritative and legally binding. Extract IQWiG Reports – Commission No. H18-02 Targeted lung denervation using catheterablation for chronic obstructive pulmonary disease – Addendum to Commission H16-011 Extract
Catheterablation of atrial arrhythmias in cardiac amyloidosis: Impact on heart failure and mortality. Atrial arrhythmias (AA) commonly affect patients with cardiac amyloidosis (CA) and are a contributing risk factor for the development of heart failure (HF). This study sought to investigate the long-term efficacy and impact of catheterablation on HF progression in patients with CA and AA . Thirty-one patients with CA and AA undergoing catheterablation were retrospectively included (transthyretin-ATTR CA 61% and light chain-AL CA 39%). AA subtypes included atrial fibrillation (AFib) in 22 (paroxysmal in 10 and persistent in 12), atrial flutter (AFl) in 17 and atrial tachycardia (AT) in 11 patients. Long-term AA recurrence rates were evaluated along with the impact of sinus rhythm (SR
In symptomatic AF, catheterablation vs. medical therapy reduced depression and anxiety symptoms at 12 mo. Al-Kaisey AM, Parameswaran R, Bryant C, et al. JAMA. 2023;330:925-933. 37698564.
Apixaban plasma concentrations before and after catheterablation for atrial fibrillation. Catheterablation in patients with atrial fibrillation is associated with a transient increase in thromboembolic risk and adequate anticoagulation is highly important. When patients are anticoagulated with apixaban, monitoring of plasma concentrations of the drug is not routinely performed. This study and increased age, female sex, lower glomerular filtration rate, higher CHA2DS2-VASc score, use of cytochrome P450 3A4 and/or p-glycoprotein inhibitors, and use of amiodarone. Self-reported adherence was generally high. The mean intra-individual and inter-individual coefficients of variation were 29% and 49%, respectively. In patients undergoing catheterablation for atrial fibrillation, age, sex, renal
Remimazolam to prevent hemodynamic instability during catheterablation under general anesthesia: a randomized controlled trial Maintaining hemodynamic stability during cardiac ablation under general anesthesia is challenging. Remimazolam, a novel ultrashort-acting benzodiazepine, is characterized by maintaining comparatively stable blood pressure and does not influence the cardiac conduction
Efficacy and safety of Saireito (TJ-114) in patients with atrial fibrillation undergoing catheterablation procedures: A randomized pilot study. Early arrhythmia recurrences commonly occur after atrial fibrillation (AF) ablation because of irritability and inflammation of left atrium. We hypothesized that short-term use of Saireito would be effective in reducing frequent atrial tachyarrhythmias in the early-phase post-ablation. One hundred patients undergoing catheterablation for symptomatic AF were randomly assigned to either a 30-day use of Saireito or control group. The primary endpoint was total number of episodes of frequent atrial tachyarrhythmias including definite recurrent AF and frequent premature atrial contractions during the 30-day treatment period post-ablation. Three (6.0%) out
Atrial tachyarrhythmia prevention by Shensong Yangxin after catheterablation for persistent atrial fibrillation: the SS-AFRF trial Despite advances in technology and techniques, the recurrence rate of persistent atrial fibrillation (AF) following catheterablation remains high. The Shensong Yangxin (SSYX) capsule, a renowned traditional Chinese medicine formula, is used in the treatment of cardiac arrhythmias. This trial aimed to investigate whether the SSYX can improve clinical outcomes in patients who have undergone catheterablation for persistent AF. A multi-centre, randomized, double-blind, placebo-controlled clinical trial was conducted at 66 centres in China among 920 patients with persistent AF undergoing first ablation. Participants were randomized to oral SSYX, 1.6 g (.4 g
CatheterAblation or Antiarrhythmic Drugs for Ventricular Tachycardia. Patients with ventricular tachycardia and ischemic cardiomyopathy are at high risk for adverse outcomes. Catheterablation is commonly used when antiarrhythmic drugs do not suppress ventricular tachycardia. Whether catheterablation is more effective than antiarrhythmic drugs as a first-line therapy in patients treatment) to receive antiarrhythmic drug therapy or to undergo catheterablation. All the patients had an ICD. Catheterablation was performed within 14 days after randomization; sotalol or amiodarone was administered as antiarrhythmic drug therapy according to prespecified criteria. The primary end point was a composite of death from any cause during follow-up or, more than 14 days after randomization
Radiofrequency catheterablation of persistent atrial fibrillation by pulmonary vein isolation with or without left atrial posterior wall isolation: long-term outcomes of the CAPLA trial Posterior wall isolation (PWI) is commonly incorporated into catheterablation (CA) strategies for persistent atrial fibrillation (AF) in an attempt to improve outcomes. In the CAPLA randomized study, adjunctive regular follow-up including rhythm monitoring for a minimum of 3 years post CA. AF burden at 3 years post-ablation was evaluated with either 28-day continuous ambulatory ECG monitoring, twice daily single-lead ECG or from cardiac implanted device. Evaluated endpoints included freedom from any documented atrial arrhythmia recurrence after a single procedure, AF burden, need for redo catheterablation
Comparing pulsed field ablation and thermal energy catheterablation for paroxysmal atrial fibrillation: a cost-effectiveness analysis of the ADVENT trial. Pulsed field ablation (PFA) has emerged as an effective technology in the treatment of paroxysmal atrial fibrillation (AF). To evaluate the cost-effectiveness of PFA vs. thermal ablation from a US healthcare payer perspective using data from
In-hospital outcomes of catheterablation in atrial arrhythmias: a nationwide analysis of 2,901 patients with adult congenital heart disease compared to 787,995 without. Advances in pediatric cardiology and congenital heart surgery have increased the adult population with congenital heart disease (CHD), now facing long-term complications like atrial arrhythmias. Given the limited data and safety concerns in this unique and vulnerable patient group, this study analyzes in-hospital outcomes of atrial catheterablation in CHD patients versus non-CHD patients from a German nationwide real-world registry. Using health records, all atrial catheterablation procedures in Germany from 2008 to 2021 were analyzed. After adjustment for confounders, safety performance endpoints were compared between
Safety and efficacy of catheterablation in atrial fibrillation patients with heart failure with preserved ejection fraction. Catheterablation (CA) for atrial fibrillation (AF) in heart failure patients with preserved ejection fraction (HFPEF) has shown promising results in reducing mortality and improving heart function. However, previous studies have been limited by a lack of control groups
Transhepatic venous access for catheterablation of right and left side atrial arrhythmias in adults: challenges and outcomes. Electrophysiologic (EP) procedures are typically performed via the femoral venous system, but in some patients, the inferior vena cava (IVC) is unavailable. The hepatic vein has emerged as a viable alternative to femoral access, providing an inferior route
Atrial fibrillation catheterablation, brain glymphatic function, and cognitive performance. It remains unknown whether the brain glymphatic system, which is driven by the heartbeat-driven pulsation of arteries and is responsible for cerebral waste clearance, is impaired in atrial fibrillation (AF) and mediates cognitive dysfunction related to AF. The aim of this study was to assess brain glymphatic alterations in AF, their role in cognitive function, and whether catheterablation can improve glymphatic activity. In this case-control and prospective before-and-after study, patients with AF and healthy controls (HCs) were enrolled. Participants underwent brain magnetic resonance imaging and a comprehensive neuropsychological battery. Glymphatic activity was quantified by diffusion tensor