"Cefradine"

An Open-Label, Randomized, 2-Way, Crossover Bioequivalence Study of Cefradine Capsules in Healthy Chinese Volunteers. The purpose of this study was to evaluate whether test cefradine capsules and reference cefradine capsules were bioequivalent in healthy Chinese volunteers. An open-label, randomized, biperiodic, crossover design was used. In each of the 2 study periods (separated by a 1-week washout period), 250-mg single doses of either the test or reference cefradine capsule were administered to study participants under fasted and fed conditions. Blood samples were collected at intervals from predose to 8 hours afterward. In the fasting study, the 90% confidence intervals (90%CI) of the C , AUC , and AUC for the test and reference preparations were 93.7%-112.2%, 94.6%-100.8%, and 94.7

Cefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase Skin inflammation, and skin cancer induced by excessive solar ultraviolet (SUV) is a great threat to human health. SUV induced skin inflammation through activating p38 mitogen-activated protein kinase (p38) and c-Jun N-termeinal kinases (JNKs). T-LAK cell-originated protein kinase (TOPK) plays an important role in this process. Herein, the clinical data showed TOPK, phospho-p38, phospho-JNKs were highly expressed in human solar dermatitis. Ex vivo studies showed that SUV induced the phosphorylation of p38 and JNKs in HaCat and JB6 cells in a dose and time dependent manner. Molecule docking model indicated cefradine, an FDA-approved cephalosporin antibiotic

Algal Feedback and Removal Efficiency in a Sequencing Batch Reactor Algae Process (SBAR) to Treat the Antibiotic Cefradine Many previous studies focused on the removal capability for contaminants when the algae grown in an unexposed, unpolluted environment and ignored whether the feedback of algae to the toxic stress influenced the removal capability in a subsequent treatment batch. The present research investigated and compared algal feedback and removal efficiency in a sequencing batch reactor algae process (SBAR) to remove cefradine. Three varied pollution load conditions (10, 30 and 60 mg/L) were considered. Compared with the algal characteristics in the first treatment batch at 10 and 30 mg/L, higher algal growth inhibition rates were observed in the second treatment batch (11.23% to 20.81

Cephalosporins You need to be logged in to see the full monograph.LoginUSE OF CEPHALOSPORINS IN PREGNANCYDate of issue: August 2022, Version: 4A corresponding patient information leaflet on USE OF CEPHALOSPORINS IN PREGNANCY is available.Cephalosporins (commonly include: cefaclor, cefadroxil, cefalexin, cefazolin, cefixime, cefotaxime, cefpodoxime, cefradine, ceftazidime, ceftriaxone

by administration of antibiotics. Eighteen (18) mice were randomly assigned to three equal groups of six mice, namely Normal (mn group), Placebo control (mm group) and and QWBZP (DQ) treatment (mdq group). Mice were gavaged with a solution (23.33 mL·kg·day) consisting of gentamicin and cefradine to establish AAD. The DQ treatment group was gavaged with DQ for 4 days, and sterile water was used as a placebo

encourage all women to complete an online reporting form.A corresponding patient information leaflet on cephalosporin use in pregnancy is available at www.medicinesinpregnancy.org.SummaryPlease note - The latest update of this monograph does not include data published after June 2017.Cephalosporins (including cefaclor, cefadroxil, cefalexin, cefixime, cefotaxime, cefpodoxime, cefradine, ceftazidime

. Polymerase chain reaction (PCR) was used to detect the representative genes encoding resistance to commonly used β-lactam antibiotics. Highest resistance was observed for cefradine (24.03%), followed by penicillin (20.78%) and ceftazidime (20.13%). The isolation rates of β-lactam resistance genes were 53.25, 48.70, 15.58 and 14.29% for bla , bla , bla and bla , respectively, while 62 (40.26%) E. coli

Effects of Debaryomyces hansenii treatment on intestinal microorganisms in mice with antibiotics-induced diarrhea To investigate the influence of treatment on intestinal microorganisms in mice with antibiotics-induced diarrhea, mouse model of antibiotics-induced diarrhea was created by gavaging mice with mixed antibiotics (23.33 mL/kg/days) composed of gentamycin sulfate and cefradine for 5

In situ degradation of antibiotic residues in medical intravenous infusion bottles using high energy electron beam irradiation This study reported an immediate approach for the degradation of three antibiotic (amoxicillin, ofloxacin, and cefradine) residues in medical intravenous infusion bottles (MIIBs) using high energy electron beam (HEEB) irradiation. The effects of irradiation doses, initial concentrations, initial pH, and scavengers of active radicals on the degradation of three antibiotic residues (ARs) were investigated, and the results displayed that 97.02%, 97.61% and 96.87% of amoxicillin, ofloxacin, and cefradine residues could be degraded in situ through HEEB irradiation respectively. Fourier transform infrared spectroscopy (FTIR) and high performance liquid chromatography-mass

are controlled using the least expensive and safest effective agent for the shortest time that is compatible with good clinical practice.There are currently few randomized clinical studies (conducted more than 25 years ago) on the subject. In 1988 a randomized clinical trial was conducted with 243 patients undergoing TURB, three perioperative doses of cefradine were compared with placebo, observing

. Superantigen genes (speA and speC) were examined by performing PCR on isolates with the most prevalent emm genotype. All isolates were sensitive to penicillin, cefradine and ofloxacin. The highest rate of resistance was against clarithromycin (98.1 %), followed by erythromycin (97.6 %), azithromycin and clindamycin (both 97.2 %), and tetracycline (94.0 %). Among the 466 isolates, 421 (90.3 %) harboured

treated with manipulation, and cefradine was orally administered to patients in the control group. The local breast lump size, clinical symptoms and the adverse reactions in the two groups were observed before and after the treatment. The total response rates in the treatment and control group were 95.92% (94/98) and 80% (76/95) respectively. There was a significant difference in the total response rate

oral MgSO4 solution at the night before operation, and Cefradine 2.0 g (I.V.) during the induction of anesthesia, continued with tow times of intravenous Cefradine 2.0 g and 0.5% Metronidazole 100 ml at an interval of 12 hours in 24 hours after the operation. The Treatment 2 group was given the same treatment as Treatment 1, but the antibiotics would not be withdrawn until 3-5 d after operation

‡ * Cefazaflur‡ * Cefradine

Oral brodimoprim was compared with amoxicillin, cefalexin, doxycycline, roxithromycin, ampicillin, cefradine or erythromycin. In all studies, brodimoprim was initially administered as a 400 mg (adults) or 10 mg/kg (children) loading dose, and at a dosage of 200 mg/day (adults) or 5 mg/kg per day (children) thereafter; the dosages of the comparators were listed in the review . ..

of more than 99%. The phenotypic traits and molecular biology of isolated bacteria, determined their identity as Vibrio vulnificus (V. vulnificus). In addition, artificially infected L. vannamei with Vibrio vulnificus appeared with the same disease symptoms as those of naturally infected shrimp. Drug sensitivity tests showed that V. vulnificus is highly sensitive to fosfomycin, cefradine and sinomin

I, II and III (ECI, ECII and ECIII) known to cause major hospital outbreaks. All 16 isolates (100%) were sensitive to carbapenems, gentamicin, ciprofloxacin and piperacillin/tazobactam but were resistant to amoxicillin, cefradine, trimethoprim and chloramphenicol. Moreover, all isolates had a baseline resistance to ceftazidime, with a minimum inhibitory concentration of 4 mg/L. All isolates lacked