"Cefuroxime axetil"

Effects of cefuroxime axetil combined with Xingpi Yanger granules on the serum gastrin, motilin, and somatostatin levels in children with upper respiratory tract infection accompanied by diarrhea: results of a randomized trial. The purpose of the study was to investigate the effects of cefuroxime axetil combined with Xingpi Yanger granules on the treatment of upper respiratory tract infection children received routine treatment, while the children in the study group were treated with cefuroxime axetil combined with Xingpi Yanger granules. After treatment, each clinical index of the children in both groups was detected to evaluate the clinical efficacy of the different treatment methods. There were no significant differences in gender ratio, average age, mean body temperature, mean duration

Prospective Cohort Study Investigating the Safety and Efficacy of Ambulatory Treatment With Oral Cefuroxime-Axetil in Febrile Children With Urinary Tract Infection To assess the safety and efficacy of ambulatory oral cefuroxime-axetil treatment in children presenting with first febrile urinary tract infection (UTI) in terms of resolution of fever, antibiotics tolerance, bacterial resistance , and loss to ambulatory follow-up. Two-year prospective single-center evaluation of the local protocol of oral ambulatory treatment of children presenting first febrile urinary tract infection (UTI). From October 2013 to October 2015, 82 children were treated ambulatory with oral cefuroxime-axetil. The median age was 8 months. When analyzing those 82 children treated orally, 51 (62%) completed oral

Prevention of peritonitis in newly-placed peritoneal dialysis catheters: efficacy of oral prophylaxis with cefuroxime axetil - a preliminary study. Peritonitis is one of the causes of early peritoneal dialysis (PD) failure in newly-placed catheters. Antibiotic prophylaxis has been recommended to decrease the risk of infection after PD catheter placement. In this study, we compared the efficacy of parenteral versus oral prophylactic cefuroxime axetil for preventing peritonitis after placed PD catheters. In total, 67 patients (F/M: 32/35; mean age: 46.6±13.2 years) undergoing 70 percutaneous PD catheter placement procedures were included (in three patients, placement was repeated). In 37 patients (parenteral group), we administered a single intravenous (IV) 750-mg dose of cefuroxime axetil

Anaphylactic reaction due to cefuroxime axetil: A rare cause of anaphylaxis One of the most used cephalosporins in clinical practice is cefuroxime axetil. Anaphylaxis due to the administration of cefuroxime is considered a rare event. We report a case of anaphylactic reaction after the administration of cefuroxime in a child who had tolerated the drug in past exposures. Diagnostic workup

Application of Vibrational Spectroscopy Supported by Theoretical Calculations in Identification of Amorphous and Crystalline Forms of Cefuroxime Axetil FT-IR and Raman scattering spectra of cefuroxime axetil were proposed for identification studies of its crystalline and amorphous forms. An analysis of experimental spectra was supported by quantum-chemical calculations performed with the use of B3LYP functional and 6-31G(d,p) as a basis set. The geometric structure of a cefuroxime axetil molecule, HOMO and LUMO orbitals, and molecular electrostatic potential were also determined by using DFT (density functional theory). The benefits of applying FT-IR and Raman scattering spectroscopy for characterization of drug subjected to degradation were discussed.

Assay of Diastereoisomers of Cefuroxime Axetil in Amorphous and Crystalline Forms Using UHPLC-DAD A sensitive UHPLC-DAD method was developed for determination of diastereoisomers of cefuroxime axetil in bulk substance in amorphous and crystalline forms as well as in pharmaceutical preparations. Chromatographic separation was achieved on Kinetex C-18 (100 mm × 2.1 mm, 1.7 µm) column with mobile phase consisting of 0.1 % formic acid:methanol (88:12, v/v), at the flow rate of 0.7 mL min and total run time of 3 min. The wavelength of the DAD detector was set at 278 nm. Inter-day precision (RSD) was less than 3 % and accuracy level ranged between 98.31 and 104.99 %. Degradation products of cefuroxime axetil in aqueous solutions and in the solid state were identified with a EIS-Q-MS mass

Bioequivalence study of 500 mg cefuroxime axetil film-coated tablets in healthy volunteers. The aim of the study was to investigate the bioavailability of a generic product of 500 mg cefuroxime axetil film-coated tablets (test) as compared to that of a branded product (reference) at the same strength to determine bioequivalence and to apply for regulatory approval. The secondary objective

Effects of amlodipine on the oral bioavailability of cephalexin and cefuroxime axetil in healthy volunteers. In this study, the authors compared the effects of amlodipine (AML) on the bioavailability of cephalexin (LEX) and cefuroxime axetil (CXM). Twenty-four healthy men were randomized to 4 treatments according to a crossover design with a 14-day washout. After an overnight fast, they were

Development of gastroretentive drug delivery system for cefuroxime axetil: in vitro and in vivo evaluation in human volunteers. The objective of this investigation was to develop the cefuroxime axetil sustained-release floating tablets to prolong the gastric residence time and compare their pharmacokinetic behavior with marketed conventional tablets (Zocef). The floating tablets were developed

Drug-induced linear IgA bullous dermatosis after discontinuation of cefuroxime axetil treatment Linear immunoglobulin A (IgA) bullous dermatosis (LABD) is a rare autoimmune blistering disorder. The disease may be either idiopathic or druginduced. Over the past 30 years, approximately one hundred LABD cases have been described as induced by a wide range of drugs, chiefly antibiotics. We report the case of 37-year-old woman who developed pruritic bullous lesions spread all over the body three weeks after her last dose of cefuroxime axetil. Antibiotic therapy was started due to rhino-sinusitis. In most reported cases of drug-induced LABD, skin lesions occur within the time of drug administration. However, the onset of disease may be even after discontinuation of treatment. It seems

. • Cefuroxime may be considered as an alternative if amoxicillin-clavulanate is not a suitable option (e.g., issues with tolerability or side effects). In the primary care setting, it is expected that oral cefuroxime (cefuroxime axetil) will be more readily available (see note about parenteral antibiotics in Table 5). Recommendation 7Prescribe amoxicillin-clavulanate empirically for patients hypersensitivity to cephalosporin antibiotics.• A higher dose of oral cefuroxime axetil (500 mg BD) may be required to effectively treat acute uncomplicated pyelonephritis.• For patients with type 1 penicillin allergy, cross-reactivity to cefuroxime is unlikely due to structural differences in their side chains.37 However, caution is still advised.• Medications that reduce gastric acidity (e.g

days Uncomplicated Amoxicillin/clavulanate 875/125 mg BID 5–7 days Complicated Azithromycin 500 mg x 1 dose, then 250 mg daily x 4 days 5 days Uncomplicated Cefuroxime axetil 500 mg BID 5–7 days Uncomplicated Ciprofloxacin 500 mg BID 5–7 days Pseudomonas risk Doxycycline 100 mg BID 5–7 days Uncomplicated Levofloxacin 750 mg daily 5–7 days Complicated Pseudomonas risk Moxifloxacin 400 mg daily 5

Meropenem hydrate Cefotaxime sodium Cefuroxime axetil

. How long should a patient with erythema migrans be treated?Recommendation:1. We recommend that patients with erythema migrans be treat-ed with either a 10-day course of doxycycline or a 14-day course of amoxicillin or cefuroxime axetil rather than longer treatment courses (strong recommendation, moderate- quality evidence). Comment: If azithromycin is used , very low-quality evidence).3. For the treatment of Lyme carditis, we suggest 14–21 days of total antibiotic therapy over longer durations of treatment (weak recommendation, very low-quality evi-dence). Comment: Oral antibiotic choices for Lyme car-ditis are doxycycline, amoxicillin, cefuroxime axetil, and azithromycin.XX. Should patients being evaluated for acute

, the convalescent-phase serum sample should be collected at least 2–3 weeks after collection of the acute-phase serum sample. VI. WHAT ARE THE PREFERRED ANTIBIOTIC REGIMENS FOR THE TREATMENT OF ERYTHEMA MIGRANS?Recommendation: 1. For patients with erythema migrans, we recommend using oral antibiotic therapy with doxycycline, amoxicillin, or cefuroxime axetil (strong recommendation; moderate quality of evidence).Comment: For patients unable to take both doxycycline and beta-lactam antibiotics, the preferred second-line agent is azithromycin. VII. HOW LONG SHOULD A PATIENT WITH ERYTHEMA MIGRANS BE TREATED?Recommendation: 1. We recommend that patients with erythema migrans be treated with either a 10-day course of doxycycline or a 14-day course of amoxicillin or cefuroxime axetil rather than

antacid and cefuroxime axetil. A significant difference in counseling scores was found between pharmacies located in Ajman and Sharjah (p = 0.01). Also, there was a significant difference in dispensing scores between independent and chain pharmacies (p = 0.003). The findings revealed inadequate counseling and dispensing practice by CPs. This study highlighted the need for continuous professional