"Cervical conization"

Effects of adding low-dose esketamine to sufentanil and propofol sedation during cervical conization: a single-centre, randomized controlled trial. Cervical conization is a brief but painful procedure that can be performed under sufficient sedation with propofol and opioids. However, this sedation approach comes with a high risk of sedation-related adverse events (SRAEs). Esketamine, an N-methyl -d-aspartate (NMDA) receptor antagonist, causes less cardiorespiratory depression than opioids. The aim of this study was to assess the efficacy and safety of adding a low dose of esketamine to propofol and sufentanil sedation as an opioid-reduced regimen. A total of 122 consecutive patients with ASA I-II, body mass index < 30, and STOP-BANG score < 3 who underwent cervical conization were enrolled

Factors Associated with Lesion Recurrence Following Cervical Conization. To investigate the factors influencing lesion recurrence during the follow-up after cervical conization and evaluate the clinical value of human papillomavirus (HPV) testing and thinprep cytology test (TCT) in postoperative follow-up patients undergoing cervical conization. A total of 289 patients with cervical lesions who underwent primary cervical conization at our hospital between January 1, 2018, and December 31, 2019, were included in this study. TCT, HPV testing, and colposcopy were performed every 6 months for a follow-up period of 3 years. Based on the follow-up results, the patients were divided into recurrence and non-recurrence groups. The basic and colposcopic data of the two groups were analyzed to identify

Increasing trends of cervical conization with lymph node evaluation for fertility-sparing surgery in early cervical cancer. To examine uptake, characteristics, and survival outcome of less-radical fertility-sparing surgery with cervical conization and lymph node evaluation (Cone-LN) in reproductive age patients with early cervical cancer. This retrospective cohort study examined the National Cone-LN. In a propensity score-weighted model, the Cone-LN and Trach-LN groups had comparable overall survival (7-year rates, 98.9% vs 97.8%). Similar associations were observed for patients with squamous, adenocarcinoma / adenosquamous, T1a classification, and T1b(≤2 cm) classification. The current population-based analysis suggests that the performance of cervical conization with lymph node

Cardiopulmonary Adverse Events of Remimazolam versus Propofol During Cervical Conization: A Randomized Controlled Trial. This study aimed to compare the cardiopulmonary safety of remimazolam and propofol in patients undergoing cervical conization. This was a single-blind, parallel, randomized controlled study. A total of 204 patients scheduled for day surgery of cold knife cervical conization ratio (OR) [95% CI], 0.43 [0.28 to 0.65]; < 0.001). The remimazolam group showed lower incidences of hypotension and hypoxemia compared to the propofol group ( = 0.01 for both). No significant differences were observed in the overall alfentanil dosages administered, bradycardia, bodily movement, or time to losing consciousness between the two groups. In patients who underwent cold knife cervical

Cervical conization before primary radical hysterectomy has a protective effect on disease recurrence in early cervical cancer: A two-center matched cohort study according to surgical approach. To ascertain whether cervical conization before radical hysterectomy (RH) has a protective effect on survival outcomes in early cervical cancer, taking into account the surgical approach. From cervical control (3-year DFS rate, 95.7% vs. 82.9%; P = 0.005). In multivariate analysis adjusting for cervical tumor size and adjuvant treatment, conization was identified as an independent favorable prognostic factor for DFS (adjusted HR, 0.318; 95% CI, 0.134-0.754; P = 0.009). Preoperative cervical conization might reduce the disease recurrence rate in early cervical cancer patients who undergo primary MIS RH.

Immunotherapy in patients with local HPV infection and high-grade squamous intraepithelial lesion following uterine cervical conization. To establish the clearance of cervical human papillomavirus (HPV) infection following postoperative immunotherapy with inosine pranobex in women receiving surgical treatment of established high-grade squamous intraepithelial lesion (HSIL) of the uterine cervix significantly differed ( < .05) with regard to clearing the most common high-risk HPV genotypes (HPV 16 and HPV 56). Inosine pranobex immunotherapy in HPV-positive patients following cervical conization significantly increased the clearance of viral infection with high-risk genotypes and reduced relapse of HSIL.

Menopausal status is associated with a high risk for residual disease after cervical conization with positive margins. We aimed to determine demographic and clinicopathological predictors for residual disease in women with cervical intraepithelial neoplasia (CIN 2/3) with endocervical cone margin involvement. A cross-sectional study was conducted. The eligible patients were women who underwent

Cerclage is associated with the increased risk of preterm birth in women who had cervical conization. The aim of this study was to determine the effect of cerclage in women who underwent cervical conization. Study data were collected from the Korea National Health Insurance Claims Database of the Health Insurance Review and Assessment Service for 2009-2013. Women who had a conization in 2009

Evaluation of optimal timing of pregnancy after cervical conization PROSPERO International prospective register of systematic reviews Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied for this submission

Pregnancy Outcomes Following Cervical Conization or Loop Electrosurgical Excision Procedures. Conservative excisional measures used to manage cervical dysplasia are often cited as risk factors for preterm labor in subsequent pregnancies. We performed an evidence-based review of the obstetric complications following excisional procedures for cervical dysplasia in women of reproductive age

Cervical Conization and the Risk of Preterm Birth: A Population-Based Multicentric Trial of Turkish Cohort Cold Knife Conization (CKC) is one of the most effective methods for the treatment of Cervical Intraepithelial Neoplasia (CIN). Some studies showed a relation between preterm birth and the treatment of CIN; on the other hand, other studies do not show such a relationship. The present study

Regeneration Process After Cervical Conization for Cervical Intraepithelial Neoplasia. To investigate whether there is a regeneration process after cervical conization and, if it exists, how much of the cervix will regenerate and when regeneration will be completed. This was a prospective observational study of women undergoing conization for cervical intraepithelial neoplasia. Transvaginal

Knowledge of HPV and Surgery among Women Who Underwent Cervical Conization: A Korean Multi-Center Study Human papillomavirus (HPV) infection is a well-known cause of cervical cancer, which, along with its precursors, can be diagnosed and treated with cervical conization (CC). This study aimed to assess HPV- and procedure-related knowledge among women who had undergone CC. Between February

Cardiac arrest during spinal anesthesia for cervical conization: a case report Spinal anesthesia is regularly performed worldwide and is an integral part of the modern day anesthesia practice. Although unexpected cardiac arrests during this procedure are very rare, medical professionals should be aware of the potential for this complication. In making the decision to use spinal anesthesia

Pseudoaneurysm of uterine artery causing intra-abdominal and vaginal bleeding after cervical conization Uterine arterial pseudoaneurysm is a very rare condition usually associated with postpartum hemorrhage. It almost never occurs after cervical conization; however, since ruptured pseudoaneurysm could be life threatening, we should consider the possibility of vascular injury such as pseudoaneurysm when we find a patient with vaginal bleeding after the process of surgical operation. Emergency arterial embolization is a well established therapeutic option to control the ruptured pseudoaneurysm. This is a case report of uterine arterial pseudoaneurysm causing intra-abdominal bleeding followed by cervical conization, which was successfully treated by uterine artery embolization.

Positive Surgical Margin, HPV Persistence, and Expression of Both TPX2 and PD-L1 Are Associated with Persistence/Recurrence of Cervical Intraepithelial Neoplasia after Cervical Conization To determine the clinicopathologic and immunohistochemical predictors of the persistence/recurrence of cervical intraepithelial neoplasia (CIN) after cervical conization. Medical records of 502 patients who received cervical conization treatment of CIN between 2005 and 2012 were reviewed. The clinicopathologic parameters were analyzed using Cox hazard regression. Fifty patients with CIN persistence/recurrence were matched to 50 cases without CIN persistence/recurrence. These 100 cervical specimens were assessed for expression of insulin-like growth factor II messenger RNA (mRNA)-binding protein 3 (IMP3

Effect of pre-operative cervical conization before hysterectomy on survival and recurrence of patients with cervical cancer: a systematic review and meta-analysis. PROSPEROInternational prospective register of systematic reviews Print | PDFEffect of pre-operative cervical conization before hysterectomy on survival and recurrence of patients with cervical cancer: a systematic review and meta . Further detail is provided here.CitationHengxi Chen, Lin Han, Yali Chen. Effect of pre-operative cervical conization before hysterectomy on survival and recurrence of patients with cervical cancer: a systematic review and meta-analysis.. PROSPERO 2023 CRD42023398756 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023398756Review questionTo determine the effect of pre

Uterine Artery Pseudoaneurysm After Uterine Cervical Conization. Uterine artery pseudoaneurysm is a rare postoperative complication. Several case reports describe this occurring after cesarean deliveries, typically presenting as delayed postoperative bleeding. A 26-year-old woman (gravida 1, para 0010) underwent a cervical cold-knife conization. She later presented three times over the symptoms. Injury to the uterine artery causing pseudoaneurysm formation can cause persistent vaginal hemorrhage after cervical conization and may elude diagnosis by arteriography.

Cervical conization doubles the risk of preterm and very preterm birth in assisted reproductive technology twin pregnancies. Does cervical conization add an additional risk of preterm birth (PTB) in assisted reproduction technology (ART) singleton and twin pregnancies? Cervical conization doubles the risk of preterm and very PTB in ART twin pregnancies. ART and cervical conization are both risk Pathology register. Cervical conization included both cold knife cone and LEEP (loop electrosurgical excision procedure) but not cervical biopsies. The main outcomes measures were PTB (PTB ≤ 37 + 0 gestational weeks), very preterm birth (VPTB ≤ 32 + 0 gestational weeks) and preterm premature rupture of membranes (PPROM). In all 16 923 ART singletons and 4829 ART twin deliveries were included. A random

Diagnostic Cervical Conization for Persistent Infection or Integration of HPV For the patients with cervical persistent infection or integration of HPV, we has designed a program to perform cervical conization for certain patients to earlier and better diagnose and cure the diseases of HPV infection and related cervical intraepithelial neoplasia/cancer. For the patients with cervical persistent infection or integration of human papillomavirus, the incidence of suffering cervical cancer or percancerous lesions increases. As the biopsy guided by colposcopy might miss some lesions, the cervical conization plays a role for the patients with high risk factors to diagnose the related cervical diseases. In this study, we has designed a program to perform cervical conization for certain patients