Adjunctive chlorhexidine for gingival health in orthodontic patients MenuNO BIAS. NO MISINFORMATION. NO SPIN. JUST WHAT YOU NEED!The Dental ElfHomeAboutCategoriesPodcastsSearchHome » Posts » Dentistry » orthodontics »Adjunctive chlorhexidine for gingival health in orthodontic patientsNo Responses »MAY32023Posted byDerek RichardsPatients undergoing fixed appliance orthodontic treatment are more prone to gingivitis, periodontitis and white spot lesions, consequently good oral hygiene is essential. Chlorhexidine is a commonly used chemotherapeutic agent used as a short-term adjunct to periodontal treatment and for the reduction of bacteria associated with caries and periodontal disease.The aim of this review was to assess the efficacy of chlorhexidine products (mouthwashes, toothpastes, gels
Herbal Mouth Rinses May Be Less Cytotoxic to Fibroblasts and SCAPs Than Chlorhexidine Skip NavigationUniversity: Home | Calendar | MapsCATs HomeWhat is a CAT?CAT MentorsSearch CATs LibrarySubmit a CATClinical CAT videosEvidence-based Practice ProgramDental School HomeORAL HEALTH EVIDENCE-BASED PRACTICE PROGRAMView the CAT printer-friendly / share this CATTitle Herbal Mouth Rinses May Be Less Cytotoxic to Fibroblasts and SCAPs Than ChlorhexidineClinical Question Do human gingival fibroblasts and SCAPs exposed to chlorhexidine gluconate mouth rinse demonstrate increased cytotoxicity as compared to those exposed to an herbal mouth rinse?Clinical Bottom Line Human gingival fibroblasts and oral stem cells of the apical papilla (SCAPs) demonstrate statistically significant increased cytotoxicity
Chlorhexidine Gluconate for Skin Preparation During Catheter Insertion and Surgical Procedures Chlorhexidine Gluconate for Skin Preparation During Catheter Insertion and Surgical Procedures | CADTH Skip to main content * About * Collaboration/Outreach * Patient/Community * Careers * Contact * My CADTH * FR * Reports * Reports * Reimbursement Review * Health Technology Workspaces Registration * Submit a Request * CADTH Topic Request Form * Who and What is Eligible * News & Events * News * Symposium * CADTH in Conversation with... * Events * Email: requests@cadth.ca * About * Collaboration/Outreach * Patient/Community * Careers * Contact * My CADTH Breadcrumb 1. Home 2. Chlorhexidine Gluconate for Skin
[ANZEN]Revisions of PRECAUTIONS: Medical Devices Containing Chlorhexidine Gluconate or Chlorhexidine Hydrochloride posted Revisions of PRECAUTIONS | Pharmaceuticals and Medical Devices AgencyPlease make JavaScript on and see this site. * Jump to body * * * * * * * * * Navigation of each product typeOur recommended contents * for Regulatory authorities * for Healthcare professionals ) November 30, 2017 Medical Devices Containing Chlorhexidine Gluconate or Chlorhexidine Hydrochloride Revision of Precautions in the Package Inserts of Medical Devic..
Antiseptic efficacy and plasma chlorhexidine levels following two different methods of application of 1% aqueous chlorhexidine gluconate for skin disinfection in preterm newborns: a randomized controlled trial. Many neonatal units have started using Chlorhexidine gluconate for neonatal skin antisepsis. However, there is in-vitro evidence of inhibition of neurite growth. The current study aimed to compare two methods of its local application, for the extent of systemic absorption and antiseptic efficacy. Parallel group, blinded, randomised trial, at a Level III, neonatal intensive care unit. Between December 2020 to July 2022, neonates from 28 to 34 weeks gestation, were randomized to local skin antisepsis by either- (a) 1% aqueous chlorhexidine (CHG aq) followed by cleansing off the residual
Cetylpyridinium chloride and chlorhexidine show antiviral activity against Influenza A virus and Respiratory Syncytial virus in vitro. The oral cavity is the site of entry and replication for many respiratory viruses. Furthermore, it is the source of droplets and aerosols that facilitate viral transmission. It is thought that appropriate oral hygiene that alters viral infectivity might reduce the spread of respiratory viruses and contribute to infection control. Here, we analyzed the antiviral activity of cetylpyridinium chloride (CPC), chlorhexidine (CHX), and three commercial CPC and CHX-containing mouthwash preparations against the Influenza A virus and the Respiratory syncytial virus. To do so the aforementioned compounds and preparations were incubated with the Influenza A virus
Povidone Iodine vs Chlorhexidine Gluconate in Alcohol for Preoperative Skin Antisepsis: A Randomized Clinical Trial. Preoperative skin antisepsis is an established procedure to prevent surgical site infections (SSIs). The choice of antiseptic agent, povidone iodine or chlorhexidine gluconate, remains debated. To determine whether povidone iodine in alcohol is noninferior to chlorhexidine follow-up was on July 1, 2020. Over 18 consecutive months, study sites were randomly assigned each month to either use povidone iodine or chlorhexidine gluconate, each formulated in alcohol. Disinfectants and skin application processes were standardized and followed published protocols. Primary outcome was SSI within 30 days after abdominal surgery and within 1 year after cardiac surgery, using
Influence of chlorhexidine dentin disinfection on universal adhesive performance: Interfacial adaptation and bond strength assessments. This study aimed to investigate the effect of chlorhexidine (CHX) cavity disinfectant on interfacial microleakage and micro-tensile bond strength (μTBS) of a universal adhesive bonded to dentin in both self-etch (SE) and etch-and-rinse (ER) modes. Class I
Direct and residual antimicrobial effect of 2% chlorhexidine gel, double antibiotic paste and chitosan- chlorhexidine nanoparticles as intracanal medicaments against Enterococcus faecalis and Candida albicans in primary molars: an in-vitro study. Thorough disinfection of root canals in primary molars may be complicated by the complex root canal morphology. This in-vitro study aimed to compare direct and residual antimicrobial effect of 2% chlorhexidine (CHX) gel, 500 mg/ml double antibiotic paste (DAP) and chitosan-chlorhexidine nanoparticles (CS-CHX NPs) as intracanal medicaments against Enterococcus faecalis (E. faecalis) and Candida albicans (C. albicans) in primary molars. Mesial roots of 63 mandibular second primary molars were infected with E. faecalis and C. albicans. Teeth were
2% chlorhexidine gluconate aqueous versus 2% chlorhexidine gluconate in 70% isopropyl alcohol for skin disinfection prior to percutaneous central venous catheterisation: the ARCTIC randomised controlled feasibility trial. Catheter-related sepsis (CRS) is a major complication with significant morbidity and mortality. Evidence is lacking regarding the most appropriate antiseptic for skin tertiary-level neonatal intensive care units. Preterm infants born <34 weeks' gestation scheduled to undergo PCVC insertion. Skin disinfection with either 2% chlorhexidine gluconate (CHG)-aqueous or 2% CHG-70% isopropyl alcohol (IPA) before PCVC insertion and at removal. Proportion in the 2% CHG-70% IPA arm with a colonised catheter at removal. Rates of: (1) CRS, catheter-associated sepsis (CAS), and CRS
Bathing with 2% chlorhexidine gluconate versus routine care for preventing surgical site infections after pancreatic surgery: a single centre randomised controlled trial. To investigate whether bathing with 2% chlorhexidine gluconate (CHG) reduces the incidence of surgical site infection (SSI) in patients undergoing routine pancreatic surgery. A randomised controlled trial was conducted % chlorhexidine gluconate could potentially reduce the incidence of SSI for the patients scheduled to undergo pancreatic surgery which further well-designed clinical trials are warranted.
Effect of chlorhexidine, povidone-iodine, and hydrogen peroxide irrigation on pain and swelling after mandibular third molar surgery: randomized controlled trial. The objective of this study was to compare the effects of irrigation solutions containing chlorhexidine, povidone-iodine, or hydrogen peroxide on pain and swelling following mandibular third molar surgery. This prospective randomized controlled trial employed a single-blind design. Overall, 112 patients were randomized to four groups based on the antiseptic assigned for the intervention: control, chlorhexidine (CHX), povidone-iodine (PI), and hydrogen peroxide (HP). The patients were followed up on days 1, 3, 7, and 15 after surgery, and pain and swelling were assessed. Data were analysed using ANOVA and post hoc multiple comparison
The positive effects of preoperative chlorhexidine rinse to reduce postoperative pneumonia after kidney transplantation surgery. Postoperative pneumonia is one of the most observed hospital-acquired infections and increases the postoperative mortality rate. Further, it drives the healthcare systems under a severe financial burden. Preventing postoperative pneumonia is an incredibly challenging issue for clinicians. Since immunosuppression therapy, the patients who had kidney transplants are more vulnerable to postoperative infections. There is no data in the scientific literature focusing on the effects of preoperative oral care with chlorhexidine antiseptic solutions on postoperative pneumonia in kidney transplantation surgery cases. In the present research, we studied this topic
Evaluating the effects of chlorhexidine and vitamin c mouthwash on oral health in non-surgical periodontal therapy: a randomized controlled clinical trial. Chlorhexidine (CHX) is the most commonly used mouthwash with proven antiplaque and antibacterial activity. The aim is to evaluate the effect of vitamin C (VitC) in CHX mouthwash on plaque accumulation and gingivitis, and to compare it with CHX
Preliminary cytotoxicity assessment of Jaftex vs. chlorhexidine mouthwashes on human gingival fibroblasts and oral squamous cell carcinoma. Jaftex is a new herbal mouthwash that consists of the aqueous extract of Jaft oak, thymus, and the aqueous extract of Satureja Bachtiarica. Its cytotoxicity remains unknown. The sample size was determined as 180 specimens as 3 specimens for each of the 60 different combinations of 2 mouthwashes, 2 cell lines, 3 exposure times (24, 48, 72 h), and 5 mouthwash doses. Also, there were 36 positive and negative controls. Jaftex 1% and chlorhexidine 0.2% were sterilized and diluted 1:2, 1:4, 1:8, 1:16, and 1:32 of the original concentration. Each drug dilution was made available in triplicate. OCC and HuGu cells were exposed to these concentrations at 37 °C
Universal vs Targeted Chlorhexidine Bathing and Nasal Decolonization in Hospitalized Patients. The ABATE Infection trial investigated the effects of universal bacterial decolonization with chlorhexidine for patients in non-intensive care unit settings to reduce hospital-onset bacteremia and fungemia (HOB) events. Among patients with medical devices (central venous catheters, midline catheters
Comparative evaluation of chlorhexidine and benzalkonium chloride pretreatments on bond strength durability of immediate dentin sealing with universal adhesive: an in vitro study. Effective and durable bonding of immediate dentin sealing (IDS) is a crucial factor in the success of adhesive-bonded restorations. This study aimed to investigate the influence of chlorhexidine (CHX) and benzalkonium
Incidence and risk factors for clinical omphalitis among neonates in Eastern Uganda using chlorhexidine gel for cord care: a community-cohort study. Omphalitis is a bacterial infection of the umbilicus and/or surrounding tissues, occurring primarily in the neonatal period. Whereas it is known to be a major route of localized and often systemic infection, studies describing incidence and risk factors remain scanty, especially in resource limited settings where the condition is thought to be common. We assessed the incidence and risk factors for omphalitis among neonates born to women who received a birth kit containing chlorhexidine for umbilical cord care after birth in Eastern Uganda. The BabyGel trial was registered in the Pan African Clinical Trial Registry -(PACTR202004705649428
Chlorhexidine vs Routine Foot Washing to Prevent Diabetic Foot Ulcers: A Randomized Clinical Trial. Foot ulcers are a common and feared complication for people with diabetes because 20% of foot ulcers become infected and lead to a lower extremity amputation. To evaluate the effect of daily foot care using chlorhexidine wipes vs soap-and-water wipes for 1 year on the risk of developing new foot . Participants were randomly assigned 1:1 to receive either soap-and-water wipes (control group) or 2% chlorhexidine wipes (chlorhexidine group). Intention-to-treat data analysis was conducted from October 5, 2023, to April 24, 2024. Daily use of a 2% chlorhexidine wipe or a soap-and-water wipe on the feet for 1 year. Wipes were nearly identical in color, size, shape, thickness, feel, and scent. Both
Neonatal skin antisepsis with alcohol-based compared to aqueous 2% chlorhexidine, used in moderate preterm infants or extremely preterm infants after the first week of life, is safe and may be associated with a reduced incidence of catheter-related blood Skin antisepsis is one of the most important bundle measures to decrease central line-related bloodstream infections (CRBSIs). However , in the neonatal population, the use of alcoholic chlorhexidine is limited by the risk of skin lesions. We hypothesised that skin antisepsis with alcohol-based 2% chlorhexidine instead of aqueous 2% chlorhexidine could reduce the incidence of CRBSI without increasing skin complications. We conducted a double cohort study comparing two periods of 3 years, first using aqueous and second using alcohol-based