"Cinchocaine"

Systemic allergic contact dermatitis associated with topical diltiazem and/or cinchocaine.

Postoperative topical analgesia of hemorrhoidectomy with policresulen and cinchocaine: a prospective and controlled study. To evaluate the effects of topical policresulen and cinchocaine in the postoperative pain behavior of open hemorrhoidectomy. We conducted a prospective, double-blinded, controlled study. The control group received the usual guidelines with oral medications. The topical treatment group received, in addition, the application of the ointment and was comprised of two subgroups (policresulen + cinchocaine, and placebo). Pain intensity was recorded with the visual analogue scale. 43 patients were operated on: control group - n = 13, one excluded; placebo - n = 15; and policresulen + cinchocaine - n = 15. The mean age was 45.98 years and 37.2% were men. The average pain

Treating rectal and anal disorders during breastfeeding SPS - Specialist Pharmacy ServiceAbout Log in RegisterNHSGuidanceEventsPlanningTrainingPublicationsTools SearchCOVID-19PGDsAdministeringCautions and contraindicationsDosingDeprescribingMore Treating rectal and anal disorders during breastfeedingPublished 19 March 2024Topics: Cinchocaine · Diltiazem · Gastrointestinal disorders · 4 more breastfeeding.Haemorrhoids and related conditionsLocal anaesthetics (such as cinchocaine or lidocaine), corticosteroids (such as hydrocortisone or prednisolone) and zinc oxide may be used topically and rectally to treat haemorrhoids and related conditions during breastfeeding, and they are often available as combination products.Some of the commonly-used products (Anusol products, Germoloids, Proctosedyl, Scheriproct

of a topical haemorrhoid treatment, for example based on the local anaesthetic cinchocaine, is between £4 and £10 for a 30 g tube of ointment. These prices are taken from the BNF. Non-surgical and surgical comparators are available in secondary care. Table 1 lists spell costs (the cost of a person's entire hospital stay, which could include multiple episodes), taken from the 2010 costs for NHS Hertfordshire

with a local anesthetic effect. To investigate the potential of rectal suppositories containing CQ and AP extracts to alleviate symptoms of hemorrhoids compared with the commercialized rectal suppository containing hydrocortisone and cinchocaine. Hemorrhoid outpatients ( = 105) with different severity grades (I, II, or III) from eight hospitals in northern Thailand were included in this study. Hemorrhoid

anaesthetics by using a caine mix (benzocaine, tetracaine, and cinchocaine) in the baseline series, and evaluate its efficiency as compared with benzocaine alone. We reviewed the results of 2736 patch tests performed between 2000 and 2010, identifying patients with positive reactions to caine mix or to one of seven local anaesthetics. One hundred and twelve patients (4.1%) had at least one allergic reaction to local anaesthetics; 86 were tested with all seven local anaesthetics, resulting in 71 reactions in 53 patients. Cinchocaine gave the most reactions (50.7%); these occurred as a single reaction in 83.3% of patients, mostly with current or past relevance (97%). Benzocaine represented 22.5% of reactions, many of which were non-relevant (44%) or resulting from cross-reactions with para-compounds. Almost

Evaluation of two local anaesthetic sprays for the relief of post-episiotomy pain. Aerosol formulations of lignocaine (5%) and cinchocaine (2%) were compared with a water-only placebo spray in a single-dose study in 76 primiparous patients complaining of moderate or severe post-episiotomy pain. In comparison with a water-only placebo, both local anaesthetic formulations gave significant relief

A comparison of alcoholic and aqueous formulations of local anaesthetic as a spray for the relief of post-episiotomy pain. A comparison of pain relief after a single perineal application of alcoholic and aqueous formulations of lignocaine (5%) spray with an aqueous formulation of cinchocaine (2%) spray was made in 72 primiparous patients complaining of moderate or severe post-episiotomy pain. All

Hyperbaric bupivacaine and hyperbaric cinchocaine: a comparison of their use for spinal anaesthesia. A new spinal analgesic formulation, 'heavy bupivacaine', was compared clinically with a commonly used agent. Sixty patients, who required spinal analgesia for transurethral prostatectomy, received either 1.5 ml of hyperbaric 0.5% cinchocaine (Nupercaine, Percaine, Dibucaine) in 6% dextrose or 2.5 cinchocaine for spinal analgesia for transurethral prostatectomy.

Comparison of hyperbaric and plain bupivacaine with hyperbaric cinchocaine as spinal anaesthetic agents. In a double-blind study, 90 patients (ASA 1 or 2) received spinal anaesthesia with 2 ml hyperbaric cinchocaine 0.5%, 4 ml hyperbaric bupivacaine 0.5% or 4 ml plain bupivacaine 0.5%. All injections were made in the left lateral position, and the patients turned supine immediately. Hyperbaric with hyperbaric cinchocaine (p less than 0.05). Onset and intensity of motor blockade were similar with all agents, but motor blockade was of significantly shorter duration with hyperbaric bupivacaine than the other agents (p less than 0.0005). Hyperbaric bupivacaine appears to be the best agent for rapid and intense sensory blockade of intermediate duration. Plain bupivacaine is more appropriate if a longer

A prospective randomised trial comparing spinal anaesthesia using hyperbaric cinchocaine with general anaesthesia for lower limb vascular surgery. One hundred and one patients were randomly allocated to have their peripheral vascular surgery performed under general anaesthesia (51 patients) or spinal anaesthesia (50 patients). Intraoperative haemodynamic changes were markedly different between

Subarachnoid anaesthesia for elective caesarean section. A comparison of two hyperbaric solutions. Forty patients who underwent elective lower segment Caesarean section under subarachnoid anaesthesia received either 2.0 ml 0.5% cinchocaine in 6% dextrose or 2.5 ml 0.5% bupivacaine in 8% dextrose via a 26-gauge needle with the patient in the left lateral position. Onset time was rapid in both groups and the distribution of maximum ascent of sensory analgesia was T1-T6. Efficacy of analgesia was greater in the bupivacaine group, although the duration of both sensory and motor blockade was shorter than following cinchocaine. There were no significant differences between the two groups either in the incidence and severity of complications or in the condition of the neonates. The high incidence

* Carticaine * Cinchocaine (Dibucaine) * Etidocaine

Effects of electrical stimulation, tetrodotoxin and cinchocaine on phosphoinositide metabolism in isolated rabbit vagus nerve.

Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine, mepyramine and some of their derivatives. The effects on glycerolipid synthesis of a series of compounds including many drugs were investigated in cell-free preparations and slices of rat liver. p . 1.6 and 0.7 mm respectively. Clofenapate (1 mm) also inhibited the incorporation of glycerol into lipids by rat liver slices without altering the relative proportions of the different lipids synthesized. The amphilic amines, mepyramine, fenfluramine, norfenfluramine, hydroxyethylnorfenfluramine, N-(2-benzoyloxyethyl)norfenfluramine, cinchocaine, chlorpromazine and demethylimipramine inhibited

) greater than chlorpromazine approximately promethazine approximately imipramine greater than cinchocaine greater than amethocaine approximately cetyltrimethylammonium greater than fenfluramine greater than amphetamine greater than 2-phenethylamine greater than cocaine approximately procaine; the most effective compounds were those with the largest and most hydrophobic non-polar substituents

The effect of stimulus intensity on alpha-adrenoceptor-mediated feedback control of noradrenaline release. 1 Mouse vas deferns stimulated transmurally (2.5 Hz, 2-32 V, 40-620 mA, FOR 45 s) responded with a twitch and a secondary contraction. Both responses were abolished by cinchocaine and were voltage-dependent. 2 In tissues previously incubated with (3H)-(--)-noradrenaline, stimulation also