"Cirrhosis"

Cirrhosis in over 16s: assessment and management Cirrhosis in over 16s: assessment and management NICE guideline Published: 6 July 2016 Last updated: 8 September 2023 www.nice.org.uk/guidance/ng50 © NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Your responsibility The recommendations in this guideline represent the view inequalities. Nothing in this guideline should be interpreted in a way that would be inconsistent with complying with those duties. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. Cirrhosis in over 16s: assessment and management (NG50

Tunnelled peritoneal drainage catheter insertion for refractory ascites in cirrhosis Tunnelled peritoneal drainage catheter insertion for refractory ascites in cirrhosis Interventional procedures guidance Published: 23 November 2022 www.nice.org.uk/guidance/ipg746 Your responsibility This guidance represents the view of NICE, arrived at after careful consideration of the evidence available. When drainage catheter insertion for refractory ascites in cirrhosis is limited but shows well-recognised complications. Evidence on the efficacy is limited in quantity and quality. Therefore, this procedure should only be used with special arrangements for clinical governance, consent, and audit or research. Find out what special arrangements mean on the NICE interventional procedures guidance page. 1.2

FibroScan for assessing liver fibrosis and cirrhosis outside secondary and specialist care FibroScan for assessing liver fibrosis and cirrhosis outside secondary and specialist care Diagnostics guidance Published: 7 June 2023 www.nice.org.uk/guidance/dg48 © NICE 2023. All rights reserved. Subject to Notice of rights (https://www.nice.org.uk/terms-and-conditions#notice-of-rights).Your are in place to review, authorise and monitor the introduction of new devices and procedures. Commissioners and providers have a responsibility to promote an environmentally sustainable health and care system and should assess and reduce the environmental impact of implementing NICE recommendations wherever possible. FibroScan for assessing liver fibrosis and cirrhosis outside secondary and specialist care

Cirrhosis Skip to main contentSkip to searchAbout usHelpSubscribeAccess through your institutionLog inBMJ Best PracticeSearchSearchSelect languageCirrhosis MENULog in or subscribe to access all of BMJ Best PracticeLast reviewed:2 Feb 2023Last updated:23 Feb 2023SummaryCirrhosis is the pathological end-stage of any chronic liver disease and most commonly results from chronic hepatitis B and C , alcohol-related liver disease, and non-alcoholic fatty liver disease.The main complications of cirrhosis are related to the development of liver insufficiency and portal hypertension and include ascites, variceal haemorrhage, jaundice, portosystemic encephalopathy, acute kidney injury and hepatopulmonary syndromes, and the development of hepatocellular carcinoma.Once a patient with cirrhosis develops

Serious liver injury being observed in patients without cirrhosis taking Ocaliva (obeticholic acid) to treat primary biliary cholangitis

Cirrhosis - Diagnosis Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies enable on these adverts.Show vendors within this categoryMarketing and advertising cookiesOnOffSkip to contentAccessibility helpSearch CKS…Search CKS…Skip to contentMenuNICECKSHealth topics A to ZCirrhosisDiagnosisDiagnosisCirrhosis:When should I suspect a diagnosis of cirrhosis?Last revised in February 2024SummaryHave I got the right topic?How up-to-date is this topic?Goals and outcome measuresBackground

Cirrhosis - Assessment Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies enable on these adverts.Show vendors within this categoryMarketing and advertising cookiesOnOffSkip to contentAccessibility helpSearch CKS…Search CKS…Skip to contentMenuNICECKSHealth topics A to ZCirrhosisDiagnosisAssessmentCirrhosis:How should I assess a person with suspected cirrhosis?Last revised in February 2024SummaryHave I got the right topic?How up-to-date is this topic?Goals and outcome measuresBackground

Cirrhosis - Investigations Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies informationDiagnosisDiagnosisAssessmentInvestigationsManagementSupporting evidenceHow this topic was developedReferencesWhen should I refer for further investigations?If a person has risk factors for, or a suspected diagnosis of, cirrhosis, consider referral for additional investigations to confirm the diagnosis, depending on local availability and referral pathways.Offer referral for transient elastography (or referral to a hepatologist or gastroenterologist

Cirrhosis - Definition Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies enable factorsComplicationsPrognosisDiagnosisManagementSupporting evidenceHow this topic was developedReferencesWhat is it?Cirrhosis is a form of liver disease which develops as a result of chronic inflammation of the liver, which can be due to a number of progressive liver conditions, usually over the course of 10–20 years [Gines, 2021; Mansour, 2023a; NICE, 2023].It is defined as the widespread disruption of normal liver structure, which becomes distorted

Cirrhosis - Complications Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies informationDefinitionPrevalenceRisk factorsComplicationsPrognosisDiagnosisManagementSupporting evidenceHow this topic was developedReferencesWhat are the complications?General risks and complicationsMalnutrition and frailtyMalnutrition can be present in up to 20% of people with compensated cirrhosis [Mansour, 2023a]. It is due to multiple factors including reduced oral intake (due to hepatic encephalopathy, ascites, or reduced

Cirrhosis - Prognosis Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies enable informationDefinitionPrevalenceRisk factorsComplicationsPrognosisDiagnosisManagementSupporting evidenceHow this topic was developedReferencesWhat is the prognosis?The natural history of cirrhosis typically follows a course of largely asymptomatic compensated disease which may progress to symptomatic decompensated disease in some people over years [Mansour, 2023b]. Progressive portal hypertension, systemic inflammation, and liver

Cirrhosis - Risk factors Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies informationDefinitionPrevalenceRisk factorsComplicationsPrognosisDiagnosisManagementSupporting evidenceHow this topic was developedReferencesWhat are the risk factors?A variety of factors increase the risk of developing cirrhosis, however, the presence of risk factors does not inevitably lead to its development. The presence of multiple risk factors may lead to a cumulative risk for cirrhosis and its complications. Common risk

Cirrhosis - Prevalence Cookies on the NICE website and servicesCookies are files saved on your phone, tablet or computer when you visit a website.We use cookies to store information about how you use the NICE website and services, such as the pages you visit.For more information, view our cookie statement.(Opens in a new window)Accept all cookiesReject cookiesEssential cookiesThese cookies enable informationDefinitionPrevalenceRisk factorsComplicationsPrognosisDiagnosisManagementSupporting evidenceHow this topic was developedReferencesHow common is it?It is difficult to assess the true prevalence of cirrhosis because the initial stages are often asymptomatic, and therefore it remains undiagnosed and presents late in many people [OHID, 2022a].The prevalence of cirrhosis has risen significantly over recent decades

Anticoagulation for stroke prevention in atrial fibrillation and treatment of venous thromboembolism and portal vein thrombosis in cirrhosis: guidance from the SSC of the ISTH secure.jbs.elsevierhealth.comVerify you are human by completing the action below.secure.jbs.elsevierhealth.com needs to review the security of your connection before proceeding.Ray ID: 8c7280781e5248b6Performance & security

Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis With progress in basic and clinical research on hepatic encephalopathy in cirrhosis worldwide, the Chinese Society of Hepatology of the Chinese Medical Association has invited experts in relevant fields to revise the 2018 "Chinese Guidelines on the Management of Hepatic Encephalopathy in Cirrhosis." The updated guidelines provide recommendations for the clinical diagnosis, treatment, and both primary and secondary prevention of hepatic encephalopathy in cirrhosis.

Management of cirrhotic ascites: Seven-step treatment protocol based on the Japanese evidence-based clinical practice guidelines for liver cirrhosis 2020 Liver cirrhosis is a severe illness, associated with multiple complications, which can lead to liver failure. One of the major complications of cirrhosis is ascites. This review describes a stepped treatment approach for the management of ascites in Japanese patients with cirrhosis. It is broadly based on the 2020 update of the Japanese clinical practice guidelines for liver cirrhosis, which is briefly compared with guidelines from Europe and the United States. Step 1 is sodium restriction at a level suitable for Japanese individuals (5-7 g/day), Step 2 is albumin treatment to counteract underlying hypoalbuminemia, Step 3 is initiation

FibroScan for assessing liver fibrosis and cirrhosis in primary care FibroScan for assessing liver fibrosis and cirrhosis in primary care Medtech innovation briefing Published: 16 June 2020 www.nice.org.uk/guidance/mib216 pathwaysSummary Summary • The technologytechnology described in this briefing is FibroScan. It is for assessing liver fibrosis and cirrhosis in primary care. • The innovative aspectsinnovative aspects of the technology are that it uses a proprietary technology to measure liver stiffness. Smaller versions of the device can be used in primary care. • The intended place in therapyplace in therapy would be in primary care for people with liver fibrosis or cirrhosis. The technology is already used extensively in specialised care settings. • The main points from the evidencemain points from

Chinese guidelines on the management of ascites in cirrhosis : Chinese Society of Hepatology, Chinese Medical Association In 2023, Chinese Society of Hepatology of Chinese Medical Association convened a panel of experts to update the Chinese guidelines on the management of ascites and associated complications in cirrhosis which was launched in 2017 and renamed this guidelines as "Guidelines on the Management of Ascites in Cirrhosis." This comprehensive resource offers essential recommendations for the diagnosis and treatment of cirrhotic ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome.

In patients with cirrhosis, what is the mechanism of thrombocytopenia in patients who do not have evidence of splenomegaly on imaging or exam? Chiefs’ Inquiry Corner – 1/24/22 – Clinical Correlations Clinical Correlations * AboutAboutAwardsPeer Review * CategoriesBedside RoundsChiefs' Inquiry CornerCORE IM PodcastDiseases 2.0EthicsEvolution and MedicineGamechanger?Healthcare PolicyHotSpotsMystery of the NYU Langone Internal Medicine Residency give quick-and-easy, evidence-based answers to interesting questions posed by house staff, both in their clinics and on the wards.Click to toggle the answers!Bellevue Inpatient: In patients with cirrhosis, what is the mechanism of thrombocytopenia in patients who do not have evidence of splenomegaly on imaging or exam? (shoutout Aaron Landau and my team

AASLD Practice Guidance: Palliative care and symptom-based management in decompensated cirrhosis AASLD Practice Guidance: Palliative care and symptom-based management in decompensated cirrhosis