"Clofezone"

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                            2022Effective Health Care Program (AHRQ)
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                            or Ampyrone or Antipyrine or Apazone or Aspirin or C-2 Azapropazone or Benorilate or Benorylate or Bromelains or Bromfenac or "BW-755C" or Celecoxib or "Choline magnesium salicylate" or "Choline magnesium trisalicylate" or clinoril or Clofazimine or Clofezone or Clonixin or "COX-1 inhibitor*" or "COX-2 inhibitor*" or "COX-2 selective inhibitor*" or Coxib* or Curcumin or "Cyclooxygenase 1 inhibitor
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                            1979Zeitschrift fur Rheumatologie
                            Comparison of clofezone and diclofenac in the treatment of out-patients suffering from activated (painful) osteoarthrosis. The effectiveness and acceptability of clofezone (Perclusone) were compared with those of diclofenac in a placebo-controlled, double-blind, cross-over trial on a group of 29 out-patients suffering from osteoarthrosis of the knee or hip. Clofezone was given at a daily dosage of 1200 mg during the first week and 600 mg during the second week; the corresponding dosages of diclofenac were 150 mg and 75 mg. The duration of the trial was 6 weeks. In order to wash out previous medication, a placebo was given for one week before and after each medication period. Eight of the patients stopped taking their drug after 1--3 weeks, namely 5 in the clofezone group and 3