Contactdermatitis Skip to main contentSkip to searchAbout usHelpSubscribeAccess through your institutionLog inBMJ Best PracticeSearchSearchSelect languageContact dermatitis MENULog in or subscribe to access all of BMJ Best PracticeLast reviewed:21 May 2023Last updated:20 Jun 2023SummaryIrritant contactdermatitis is caused by direct toxicity without prior sensitisation, and allergic contact avoidance of the causative agent, topical treatments, or possibly a short course of oral corticosteroids, phototherapy, or immunosuppressants, depending on the type of contactdermatitis and severity.Rarely, contactdermatitis can become generalised, leading to areas of dermatitis in locations distant from the site of contact with the causative agent.Other allergic conditions may be triggered by exposure
Differential diagnosis of contactdermatitis: A practical-approach review by the EADV Task Force on contactdermatitis. The diagnosis of eczema ('dermatitis') is mostly clinical and depends on the clinical history and exploratory objective findings (primary lesions, patterns). Contactdermatitis remains as an important condition in the group of eczematous disorders, with important socioeconomic and occupational relevance. Although irritant and allergic contactdermatitis have a different pathogenesis, both are characterized by a rather typical morphology, are triggered by external factors and tend to occur primarily in the area of contact with the exogenous agent. In addition, allergic and irritant dermatitis may also co-exist. The importance of diagnosing contactdermatitis, especially when allergic
Allergic contactdermatitis caused by glucose sensors and insulin pumps: A full review: Part 1: Sensors and pumps, adverse cutaneous reactions, allergens, and diabetes devices causing allergic contactdermatitis. During the past 8 years, a large number of reports have appeared on allergic contactdermatitis to glucose sensors and insulin pumps in paediatric and adult patients with type 1 diabetes for patch testing. This two-part article provides a full and detailed review of all aspects of the subject of allergic contactdermatitis to glucose sensors and insulin pumps. Part 1 begins with a general introduction to sensors and pumps, followed by the cutaneous adverse reactions that they have caused and a full account of the allergens in the diabetes devices. In addition, an overview of the glucose
T-cell mediated nickel contactdermatitis and nickel containing stents Cookie NoticeThis site uses cookies. By continuing to browse this site, you are agreeing to our use of cookies. Review our cookies information for more details.OKskip to main contentToggle site navigationAllergist Resources Ask The Expert 2023 T-Cell Mediated Nickel ContactDermatitis And Nickel Containing StentsT-cell mediated nickel contactdermatitis and nickel containing stentsQuestion:10/10/2023I have a patient with an over 20-year history of nickel contactdermatitis. She was recommended to get a stent to help with three brain aneurysms. It contains nickel. How should I proceed?Answer:This question was addressed on 12-9-2021. At the time it was not known if there was any increased risk of adverse outcomes
Allergic ContactDermatitis Following Hypoglossal Nerve Stimulator Implant. Allergic contact reactions to medical implants are underrecognized and incompletely understood, particularly in hypoglossal nerve stimulation (HGNS), an increasingly popular and effective alternative to positive airway pressure therapy for patients with obstructive sleep apnea (OSA). To document a rare case of allergic
Benzoyl Peroxide's Sensitisation Potential and Potency in Experimental Methods and Review of Contact Allergy and Allergic ContactDermatitis. Positive patch test responses to benzoyl peroxide (BPO) have been reported from patients without and with known exposure. Up to 6.5% were found in the United States and 7.8% in a study including patients from Germany, Austria and Switzerland. We provide
Chronic Prurigo Associated With Allergic ContactDermatitis: A Case Series Highlighting Textile Dyes and Fragrance Allergens. Chronic prurigo (CP) is a condition characterised by chronic pruritus and pruriginous lesions. While frequently associated with atopic dermatitis (AD), its link with allergic contactdermatitis (ACD) is less understood. To describe the clinical features, diagnostic using the Spanish Extended Baseline Series and additional allergen panels as needed, following International ContactDermatitis Research Group guidelines. Six patients were identified: four cases of CP associated with fragrances and two with textile dyes. All patients improved significantly with allergen avoidance; two required dupilumab. Histological findings and clinical responses suggested a Th2
ContactdermatitisContactdermatitis - Symptoms, diagnosis and treatment | BMJ Best PracticeSkip to main contentSkip to search * About us * Help * Subscribe * Access through your institution * Log inBMJ Best Practice * Help * Getting started * FAQs * Contact us * Recent updates * Specialties * Calculators * Patient leaflets * Videos * Evidence * Drugs * Recent updates * Prognosis * Resources * Guidelines * Images and videos * References * Patient leaflets * Evidence Log in or subscribe to access all of BMJ Best PracticeLast reviewed: 13 Jun 2022Last updated: 14 May 2019SummaryIrritant contactdermatitis is caused by direct toxicity without prior sensitisation, and allergic contact
Case Report: Mixed Airborne ContactDermatitis-Chronic Actinic Dermatitis Pattern of Parthenium Dermatitis with Response to Tofacitinib Therapy. Parthenium hysterophorus is the commonest cause of plant dermatitis in India. It classically causes airborne contactdermatitis (ABCD), characterized by pruritic, eczematous, and lichenified lesions involving predominantly the face and flexural areas
Polysensitization in the Spanish ContactDermatitis Registry (REIDAC): A 2019-2022 prospective study with cluster and network analysis. There is still limited clinical-practice data on specific clinical and patch test features, as well as on allergen clusters in polysensitization (PS). To determine the frequency, relevance, symptoms duration and risk factors in polysensitized patients and to assess possible allergen aggregation. Prospective multicentric study (January 2019-December 2022) conducted in setting of the Spanish ContactDermatitis Register (REIDAC). Clinical and patch test data of polysensitized and oligosensitized patients were compared, and risk factors of PS were investigated with logistic multivariate regression. Unsupervised hierarchical clustering and network analysis were
Trends in contact sensitization, results, and implications from a contactdermatitis clinic in Israel. The baseline series includes common allergens, evolves over time, and differs by location. Our study aims to characterize allergen sensitization trends among the Israeli population during the last two decades, compare our results to American and European registries, as well as to highlight significant allergens in additional series outside the European baseline series (OEBS). We analysed patch test results of 2086 patients from a designated contactdermatitis clinic in Tel Aviv between 2019 and 2022, compared them to European and North American registries and to 2156 patch test results conducted in Israel two decades ago. 38.6% of patients had at least one positive reaction to an allergen
Gene profiling in active dermatitis lesions strengthens the diagnosis of allergic contactdermatitis. Distinguishing between allergic and non-allergic forms of ContactDermatitis (CD) is challenging and requires investigations based on patch-testing. Early detection of allergy biomarkers in active CD lesions could refine and simplify the management of CD patients. To characterize the molecular other patients. Interestingly, the 15 patients without biomarker induction had negative PT, suggesting that they developed non-allergic CD reactions. Molecular signatures from active skin lesions may help to stratify CD patients and predict those suffering from allergic contactdermatitis.
Exploring the relationship between allergic contactdermatitis and atopic dermatitis in children: insights from a retrospective patch testing analysis. Recent years have seen significant exploration into the potential link between allergic contactdermatitis and atopic dermatitis, yielding contradictory findings. A retrospective cohort analysis of children aged 2 to 18 who underwent patch for suspected cases of allergic contactdermatitis in all children, regardless of their atopic background. Further research is warranted to potentially replace the traditional 48-h reading with a single 72-h reading in future guidelines, contributing to enhanced efficiency and cost-effectiveness in clinical practice.
New device, 'old' allergens. Allergic contactdermatitis caused by the Dexcom G7 glucose sensor. Allergic contactdermatitis (ACD) has been reported as an adverse effect from the use of several glucose sensors and insulin pumps from different manufacturers. Isobornyl acrylate (IBOA) has been identified as a major culprit sensitizer, but also other acrylates and (modified) colophonium have been
Is Food-Triggered Atopic Dermatitis a Form of Systemic ContactDermatitis? Food allergy in atopic dermatitis is mediated by complex immune interactions between genetics, diet, environment, and the microbiome. When contact between inflamed skin and food antigens occurs, contact hypersensitivity can develop. Consequently, systemic contactdermatitis (SCD) can occur after ingestion of allergenic
Evaluation of atopic diseases in patients with allergic contactdermatitis. There is controversy on whether allergic contactdermatitis (ACD) is associated with atopy. Research on eczema and the risk of ACD is mixed, and there is sparse literature on other atopic conditions. Our study examined the prevalence of several atopic conditions, including allergic rhinitis, eczema, asthma, and food
Artemisia argyi volatile oil ameliorates allergic contactdermatitis via modulating TRPA1/CGRP signaling. The leaves of Artemisia argyi Levl.et Vant. have a long history of being used to treat skin diseases such as pruritus and dermatitis in China, but the therapeutic effect on allergic contactdermatitis (ACD) is still unclear. To investigate the effect and molecular mechanisms of the volatile
Allergic contactdermatitis due to 1,6-hexanediol diacrylate in ostomy patients. Many people live with ostomies after life-saving surgery. Ostomy patients often suffer from peristomal dermatitis. Allergic contactdermatitis (ACD) has been reported, mostly due to contact allergy (CA) to topical agents. We present three patients with therapy resistant peristomal dermatitis, suggesting ACD caused