First Prenatal Diagnosis of a Niemann–Pick Disease Type C2 Revealed by a CysticHygroma: A Case Report and Review of the Literature The importance of fetal nuchal translucency was highlighted in the early 1990s as a useful first-trimester marker to identify fetal chromosomal abnormalities. Here, we report the prenatal diagnosis of a fetus with Niemann-Pick disease type C initially identified by first-trimester ultrasonographic markers and eventually confirmed by extensive genetic evaluation. The fetus of a 30-year-old woman exhibited a cystichygroma in the first trimester of pregnancy. The woman underwent chorionic villus sampling with extensive genetic investigations to identify the genetic cause of the ultrasonographic findings. Owing to normal karyotype results, further evaluation
[Analysis for the pregnancy outcome of cystichygroma fetuses and correlation with increased nuchal translucency in first trimester]. To analyze prognosis-related risk factors of first trimester cystichygroma (CH) fetuses in which nuchal translucency (NT) was found to be thickened. Tolly 216 singleton pregnancies in which fetal NT≥3.0 mm at the 11~13 weeks scan accepted invasive prenatal
Giant Cervico-Thoracic CysticHygroma in a Preterm: A Case Report Cystichygroma is a benign, painless loculated lymphatic proliferation, which occur due to a combination of sequestration from developing lymphatic system, abnormal budding of the lymphatic system or lack of development of the normal connections between venous and lymphatic drainage. We report a case of giant cervico-thoracic cystichygroma in a preterm neonate with management options and a brief review of literature.
Sudden Onset, Rapidly Expansile, Cervical CysticHygroma in an Adult: A Rare Case with Unusual Presentation and Extensive Review of the Literature Cystichygroma (CH) is a benign infiltrative malformation of the lymphatic channels. We report a case of a 28-year-old Indian female who presented with rapidly enlarging right sided neck swelling over the posterior triangle since 5 days. Complete
Management and outcomes of cystichygromas: experience of a tertiary center Cystichygroma (CH) is a fetal sonographic finding with an incidence of 1%. Chromosomal abnormalities and structural malformations are commonly related with CH. We aimed to describe our experience and determine the association between diagnosis of CH and adverse pregnancy outcome. We retrospectively reviewed data
Prenatal Ultrasound Evaluation and Outcome of Pregnancy with Fetal CysticHygromas and Lymphangiomas Cystichygroma is a type of lymphangioma, which is a vascular anomaly associated with lymphatic malformations and formed by fluid accumulation mainly located at the cervi-cofacial and axillary regions. Cystichygroma is mostly located in the neck (75%), followed by axilla (20%), retroperitoneum and intra-abdominal organs (2%), limbs and bones (2%), and mediastinum (1%). It is often associated with chromosome aneuploidies, hydrops fetalis, and even intrauterine fetal demise. The prognostic factors of the fetal cystichygroma or lymphan-gioma are chromosome abnormalities, hydrops fetalis, septations, or thickness of the cystichygroma and are associated with other major malformations. Prenatal
Systematic Review and Meta-analysis of Outcomes of Septated CysticHygromas Diagnosed in the First Trimester PROSPEROInternational prospective register of systematic reviews Print | PDFSystematic Review and Meta-analysis of Outcomes of Septated CysticHygromas Diagnosed in the First TrimesterMichelle Wang, Barbara O'Brien, Yinka OyeleseTo enable PROSPERO to focus on COVID-19 submissions . Systematic Review and Meta-analysis of Outcomes of Septated CysticHygromas Diagnosed in the First Trimester. PROSPERO 2024 CRD42024509362 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024509362Review questionThe aim of the present study is to do a systematic review of all documented cases of the outcomes (rates of aneuploidy, fetal malformations, spontaneous abortion
Outcomes and chromosomal abnormalities in Chinese fetuses with cervical cystichygroma PROSPERO International prospective register of systematic reviews Print | PDF PROSPERO This information has been provided by the named contact for this review. CRD has accepted this information in good faith and registered the review in PROSPERO. The registrant confirms that the information supplied
Title: First Trimester CysticHygroma: Does Early Detection Matter? To describe the association of abnormal outcomes with fetal cystichygroma detected when crown-rump length measures less than 45 mm, and to compare them to outcomes among fetuses with cystichygroma detected when crown-rump length measures 45-84 mm. We performed a retrospective cohort study of fetuses with first trimester nuchal cystichygroma from 2005 to 2015. A total of 212 fetuses were included. Abnormal karyotype was found in 20 of 46 (43.4%) fetuses with cystichygroma detected when crown-rump length measured below 45 mm, compared to 108 of 148 (73%) fetuses with cystichygroma detected at crown-rump lengths of 45-84 mm (p = 0.001). There were no differences in rates of major structural anomaly (27% vs 36%; p = 0.53
Robot-assisted excision of cervical cystichygroma through a retroauricular hairline approach: a case report Cystichygroma is a rare benign abnormality of the lymphatic system generally occurring in young children less than 2 years old. The standard transcervical surgical treatment of cystichygroma may often leave a permanent scar in the neck region. We report a case of cystichygroma in a 19 -month-old Asian baby girl successfully treated with robot-assisted excision through a hairline neck-lift approach. We present the use of the Yang's retractor as an instrumental advancement to this surgical approach. Treatment options for cystichygroma may be surgical or nonsurgical. We report a case of cystichygroma in a 19-month-old child successfully treated with robot-assisted excision through
An Interesting Association of CysticHygroma of the Neck and Lymphangioma Causing a Paediatric Swollen Tongue Up to 75% of lymphatic malformations occur in the head and neck region. Of these, cystichygromas and lymphangiomas have been widely reported; however they rarely occur in the same patient. We report the case of a 5-year-old girl who presented to the Department of Paediatrics of a district general hospital with a short history of recurrent, painful swelling of the anterior one-third of her tongue. She was reviewed under the joint care of the Oral and Maxillofacial Surgery and Otolaryngology Teams. Relevant past medical history included a previously excised cystichygroma from her right neck when she was aged 2 years. Diagnosis of lymphangioma was made and of the potential
The Difficult Paediatric Airway: Two Cases of large CysticHygroma This is a report of a two cases of difficult intubation experienced in paediatric surgical cases. Both the infants, aged one and three-month-old respectively, had very large cystichygroma of the neck area. Prior hematological and radiological investigations (USG and CT scan of the swelling) and preanaesthesia check up was done and cases were posted for surgical excision. Case I had difficult airway due to pressure of the tumour/cystichygroma over the airway and posed difficulty for intubation, but was managed well. Case II had respiratory distress during preoperative period. She had been postponed for surgical excision of the cystichygroma of neck twice due to the difficulties experienced during intubation. Needle aspiration
Spontaneous resolution of a recurrent axillary cystichygroma following acute infection We report a case of spontaneous resolution of a recurrent axillary cystichygroma in a 4-year-old boy. He presented with a 1-year history of a cystic lump in the left axilla, which intermittently changed in size. Ultrasound suggested it was a lipoma, with raised suspicions of vascular malformation. Scans were discussed in a multidisciplinary meeting and provisional diagnosis of lymphocele or slow flow lymphovascular malformation was made. It was surgically excised and histology confirmed the lesion to be a cystichygroma. However, it recurred within 3 weeks. The patient was booked for aspiration and treatment with sclerotic agent OK 432. He developed acute infection in the cystichygroma a week before surgical
Cervical CysticHygroma in an Adult Cystichygromas/lymphangiomas are extremely rare malformations in adults. They are usually seen in infants and children under 2 years of age. En bloc resection is difficult due to the adhesive characteristics of the tumors. Inadequate surgical intervention often leads to recurrent disease. We report herein the case of a cystichygroma/lymphangioma
Prenatal management, pregnancy and pediatric outcomes in fetuses with septated cystichygroma It has been reported that, compared with simple increased nuchal translucency, fetal cases with septated cystichygroma (CH) are more likely to face perinatal handicaps. However, pediatric outcomes and proper prenatal counseling for this anomaly have not yet been truly defined. We performed this study