Enhancing Coverage of Second Booster Dose of DPTVaccine Coverage With Parental Education: A Cluster Randomized Approach. To assess the effect of a single clinic-based educational intervention session on parents of children aged 4.5 to 5.5 years on improving the coverage of a second booster dose of the DPTvaccine. The secondary objective was to assess the coverage of second booster dose of the DPTvaccine among children aged > 6 years and to learn about the reasons behind such dropouts, if any. The study was conducted in two phases. In the first phase, a cross-sectional study was conducted among children aged > 6 years who were attending the pediatric OPD or IPD to determine the coverage of the second booster dose of DPTvaccine and possible reasons for dropout. This was followed
Effect and cost-effectiveness of educating mothers about childhood DPTvaccination on immunisation uptake, knowledge, and perceptions in Uttar Pradesh, India: A randomised controlled trial To assess the effect of health information on immunisation uptake in rural India, we conducted an individually randomised controlled trial of health information messages targeting the mothers of unvaccinated or incompletely vaccinated children through home visits in rural Uttar Pradesh, India. The study tested a brief intervention that provided mothers face-to-face with information on the benefits of the tetanus vaccine. Participants were 722 mothers of children aged 0-36 months who had not received 3 doses of diphtheria-pertussis-tetanus (DPT) vaccine (DPT3). Mothers were randomly assigned in a ratio of 1:1:1 to 1
A Clinical Trials of Adsorbed Cell-free DPTVaccine (Five-component) This is a randomized, blinded, controlled phase II and III clinical trial evaluating the immunogenicity and safety of adsorbed cell-free DPTvaccine. 320 subjects aged 7 years and older in the phase II were divided into two age groups, the ≥18 years group and the 7-17 years group, and randomized 3:1 to receive the trial vaccine
A Clinical Trial of Adsorbed Cell-free DPTVaccine (5-component) (for People Aged 6 Years and Above) Pertussis is an acute respiratory infectious disease caused by Bordetella pertussis, diphtheria is an acute upper respiratory infectious disease caused by Gram-positive Corynebacterium diphtheriae, and tetanus is a highly fatal disease caused by Clostridium tetani infection. Currently , there is no clinical trial registration of Diphtheria, tetanus, and pertussis (DPT) vaccine applicable to ≥6 years of age in China, therefore, the five-component acellular DPT combination vaccine developed by our research has a promising future. The vaccines used in China's immunization program for the prevention of pertussis, tetanus and diphtheria include the adsorbed cell-free diphtheria-tetanus-acellular
Comparison of Analgesic Effect of Direct Breast Feeding, Oral 25% Dextrose Solution and Placebo during 1st DPTVaccination in Healthy Term Infants: A Randomized, Placebo Controlled Trial. To compare analgesic effect of direct breast feeding, 25% dextrose solution and placebo as we give 1st intramuscular whole cell DPT injection to 6week - 3month old infants. Randomized, placebo controlled trial . Immunization clinic of Department of Pediatrics, LLRM Medical College. Infants coming for their 1st DPTvaccination were randomized in to three groups of 40 each. undefined The primary outcome variable was the duration of cry after vaccination. Secondary outcome variables were Modified Facial Coding Score (MFCS) and latency of onset of cry. 120 babies were equally enrolled in breast feed group, 25% dextrose
periodically faced mounting pressure and even public outrage triggered by incidents of poor-quality vaccines. We aimed to evaluate the impact of the diphtheria, pertussis, and tetanus (DPT) vaccine scandal of 2018 in China and the ensuing misinformation on vaccination, and investigate differential responses to the scandal by ethnic and socioeconomic factors. With data from January 2017 to December 2018 in Sichuan province, China, we used a difference-in-differences (DID) method to compare the changes in the county-level monthly DPTvaccinations against the hepatitis B vaccinations, both before and after the DPTvaccine scandal. We found that the number of DPTvaccinations decreased by 14.0 percent in response to the vaccine scandal and ensuing misinformation. The number of vaccinations in minority
in regional vaccination coverage and established the determinants of vaccination completion among children aged 12-23 months in Uganda. We analyzed data from the women's questionnaire for the 1995-2016 Uganda Demographic Health Survey (UDHS). Vaccine completion was defined as having received a dose of Bacillus-Calmette Guerin (BCG) vaccine; three doses of diphtheria, pertussis, and tetanus (DPT) vaccine
Calmette-Guérin (BCG) and diphtheria, pertussis, and tetanus toxoid (DPT) vaccination among newborns and infants. However, we find almost no significant effects on the measles vaccine, which is administered several months after birth.
The role of place of residency in childhood immunisation coverage in Nigeria: analysis of data from three DHS rounds 2003-2013. In 2017, about 20% of the world's children under 1 year of age with incomplete DPTvaccination lived in Nigeria. Fully-immunised child coverage (FIC), which is the percentage of children aged 12-23 months who received all doses of routine infant vaccines in their first
(5 × 5 km) of diphtheria-pertussis-tetanus (DPT) vaccine coverage and dropout for children aged 12-23 months in 52 African countries from 2000 to 2016. Estimated third-dose (DPT3) coverage increased in 72·3% (95% uncertainty interval [UI] 64·6-80·3) of second-level administrative units in Africa from 2000 to 2016, but substantial geographical inequalities in DPT coverage remained across
by antineutrophil cytoplasmic antibody (ANCA). Miscellaneous noninfectious causes of acute GN include the following: * * Guillain-Barré syndrome * * Irradiation of Wilms tumor * * Diphtheria-pertussis-tetanus (DPT) vaccine * * Serum sickness * * Epidermal growth factor receptor activation, [12] and possibly its inhibition by cetuximab [13] Previous Next
. In this prospective, 45-day study, in young women (n=46; age 18-49 years) with or without IDA, we compared iron and inflammation markers, serum hepcidin and erythrocyte iron incorporation from Fe-labeled test meals, before and 8, 24 and 36 hours (h) after influenza/DPTvaccination as an acute inflammatory stimulus. Compared to baseline, at 24-36 h after vaccination: 1) interleukin-6 increased 2-3-fold in both
for the Indian context. Programme costs included the value of personnel, vaccines, transport, maintenance, training, cold chain equipment, building and other recurrent costs. The weighted average national level cost per dose delivered was US$2.29 including vaccine costs, and the cost per child vaccinated with the third dose of diphtheria-pertussis-tetanus (DPT) vaccine (a proxy for full immunisation) was US
-implementing LGA in which 66.7% received DPT and (64%) measles. Children in the CIMCI implementing LGA were three times more likely to receive DPTVaccine (Adjusted odds ratio (AOR) 3.02, 95% confidence interval (CI) 1.55-7.98), and five and half times more likely to receive measles vaccine (AOR 5.56, 95% CI 2.76-12.54). The study concluded that community level health education activities have a positive
clustering. Public health performance was consistently important in determining the groups. For the 2-group clustering, for example, infant mortality in Group 1 was 81 per 1,000 live births compared with 51 per 1,000 in Group 2, and 67% of children in Group 1 received DPTimmunization compared with 87% in Group 2. The experts preferred four groups to fewer, on the ground that national decision makers would
, and diphtheria, pertussis and tetanus (DPT) vaccines in children aged 12 - 23 months. We also calculated the DPT1-to-DPT3 and DPT1-to-measles dropouts, and proportions of the fully immunised child (FIC). Factors predictive of FIC were explored using Chi-squared tests and multivariable logistic regression. : Overall, there was a trend of increasing vaccination coverage. The proportion of FIC varied
and dropout between DPT doses 1 and 3, using a multilevel approach. Data come from the District Level Household and Facility Survey 3 (2007-08). Individual- and household-level factors were associated with both DPT nonvaccination and dropout between doses 1 and 3. Children whose mothers had no schooling were 2.3 times more likely not to receive any DPTvaccination and 1.5 times more likely to drop out at least one dose of DPTvaccine compared with children in districts where 30% or fewer villages had subcentres. Nonvaccination with DPT in India is influenced by village- and district-level contextual factors over and above individuals' background characteristics. Dropout between DPT doses 1 and 3 is associated more strongly with demand-side factors than with village- and district-level supply-side