Pediatric Attention-Deficit/Hypearativity Disorder and DisruptiveMoodDysregulationDisorder: Analyzing National Treatment Trends. This study investigated how a disruptivemooddysregulationdisorder (DMDD) diagnosis infleunces treatment selection and sequencing in children with attention-deficit/hyperactivity disorder (ADHD). This multicenter, population-based, retrospective cohort study
Stigmatizing attitudes toward DisruptiveMoodDysregulationDisorder (DMDD) in parents vs. non-parents: Effects of medication and genetic etiology. Stigmatizing attitudes toward children with psychopathology represent a barrier to treatment and well-being, yet almost no research has investigated what contributes to these attitudes. This study examines the effects of medication treatment and genetic etiology on stigmatizing attitudes toward a relatively new and controversial disorder-DisruptiveMoodDysregulationDisorder (DMDD). Participants (159 parents, 225 non-parents) completed a vignette study on Amazon's Mechanical Turk (MTurk) in which a child displayed behaviors consistent with DMDD. The child was described as either taking psychiatric medication or not, and the vignette described
Executive function in children with disruptivemooddysregulationdisorder compared to attention-deficit/hyperactivity disorder and oppositional defiant disorder, and in children with different irritability levels. Addressing current challenges in research on disruptivemooddysregulationdisorder (DMDD), this study aims to compare executive function in children with DMDD, children with attention
Characteristic Similarities of Irritability Between Autism and DisruptiveMoodDysregulationDisorder. Irritability in children with autism spectrum disorder (ASD) is prominent and often leads to distress to both autistic children and their families. However, the nature of irritability in autism and the difference from nonautistic children have rarely been examined. This study aimed to investigate the clinical characteristics of irritability in autism, and to compare the symptom profiles with those of disruptivemooddysregulationdisorder (DMDD) in nonautistic children. Fifty-six children aged 7-17 years (mean age 10.36 ± 3.05) were recruited into this study (21 with DMDD, 21 with high-functioning autism [hfASD], and 14 healthy volunteers [HV]). Their parents completed the Aberrant
Appetite hormone dysregulation and executive dysfunction among adolescents with bipolar disorder and disruptivemooddysregulationdisorder. Appetite hormone dysregulation may play a role in the pathomechanisms of bipolar disorder and chronic irritability. However, its association with executive dysfunction in adolescents with bipolar disorder and those with disruptivemooddysregulationdisorder
A Randomized Controlled Trial of Computerized Interpretation Bias Training for DisruptiveMoodDysregulationDisorder: A Fast-Fail Study. To examine targeted, mechanism-based interventions is the next generation of treatment innovation. Biased threat labeling of ambiguous face emotions (interpretation bias) is a potential behavioral treatment target for anger, aggression, and irritability . Changing biases in face-emotion labeling may improve irritability-related outcomes. Here, we report the first randomized, double-blind, placebo-controlled targeted trial of interpretation bias training (IBT) in youths with chronic, severe irritability. Patients with current disruptivemooddysregulationdisorder (DMDD; N = 44) were randomly assigned to complete 4 sessions of active (n = 22) or sham (n
Editorial: Exemplifying a Cognitive Science-Driven Approach to Intervention Innovation: Targeting Face Emotion Labeling to Reduce Anger-Proneness in DisruptiveMoodDysregulationDisorder. Disruptivemooddysregulationdisorder (DMDD) is a condition in which children or adolescents experience chronically irritable or angry mood. These feelings typically manifest through frequent and intense
Diagnostic Trends and Prescription Patterns in DisruptiveMoodDysregulationDisorder and Bipolar Disorder. Disruptivemooddysregulationdisorder (DMDD) was introduced in DSM-5 to distinguish a subset of chronically irritable youth who may be incorrectly diagnosed and/or treated for pediatric bipolar disorder (BPD). This study characterized the rate of new treatment episodes and treated
Editorial: From Bipolar Disorder to DisruptiveMoodDysregulationDisorder: Challenges to Diagnostic and Treatment Specificity in Traumatized Youths. This valuable contribution by Findling et al. reports on trends in diagnostic patterns since the inclusion of disruptivemooddysregulationdisorder (DMDD) in the DSM-5. As the authors note, the introduction of the DMDD diagnosis was designed
DisruptiveMoodDysregulationDisorder: Symptomatic and Syndromic Thresholds and Diagnostic Operationalization. To identify the most appropriate threshold for disruptivemooddysregulationdisorder (DMDD) diagnosis and the impact of potential changes in diagnostic rules on prevalence levels in the community. Trained psychologists evaluated 3,562 preadolescents/early adolescents from the 2004
Editorial: White Matter Matters: Neurobiological Differences Between Pediatric Bipolar Disorder and DisruptiveMoodDysregulationDisorder. Think about this: Linke et al. are publishing the "first" ever study using diffusion tensor imaging (DTI) in children with disruptivemooddysregulationdisorder (DMDD). Child and adolescent psychiatrists know that these children are not new
Editorial: Antidepressants to the Rescue in Severe Mood Dysregulation and DisruptiveMoodDysregulationDisorder? Children with irritability and outbursts pose a serous therapeutic problem. Many of them have attention-deficit/hyperactivity disorder (ADHD) with emotion dysregulation, which is sometimes captured in the diagnosis of disruptivemooddysregulationdisorder (DMDD). Some follow-up data
Persistence of disruptivemooddysregulationdisorder in children with attention-deficit/hyperactivity disorder. Disruptivemooddysregulationdisorder (DMDD) is common in children with ADHD yet it is not known how persistent DMDD is in this population. As such we aimed to investigate the persistence of disruptivemooddysregulationdisorder (DMDD) in a community sample of children with ADHD
Don't Miss the Boat: Towards a Developmental Nosology for DisruptiveMoodDysregulationDisorder in Early Childhood. Disruptivemooddysregulationdisorder (DMDD) in DSM, characterized by severe, chronic irritability, currently excludes children <6 years of age. However, capitalizing on a burgeoning developmental science base to differentiate clinically salient irritability in young children may
Are youths with disruptivemooddysregulationdisorder different from youths with major depressive disorder or persistent depressive disorder? Although the disruptivemooddysregulationdisorder (DMDD) was included in the depressive disorders (DD) section of the DSM-5, common and distinctive features between DMDD and the pre-existing DD (i.e., major depressive disorder, MDD, and persistent
Trends in diagnosis of bipolar and disruptivemooddysregulationdisorders in children and youth. Rates of pediatric bipolar disorders have increased and some are concerned about diagnostic accuracy. Disruptivemooddysregulationdisorder (DMDD) was added to the DSM-5 in 2013. The purpose of this study was to assess diagnostic trends of bipolar disorders and DMDD and to identify predictors
Missing the forest for the trees? A high rate of motor and language impairments in DisruptiveMoodDysregulationDisorder in a chart review of inpatient adolescents. Youths with severe and persistent irritability have a particularly high rate of school failures and learning difficulties. The aim of this study was to determine whether inpatient adolescents with DisruptiveMoodDysregulationDisorder (DMDD) have more motor and/or language impairments compared to patients with other psychiatric disorders. A retrospective chart review of all consecutive cases admitted in two adolescent inpatient units between January 2017 and December 2018 was conducted (N = 191). All patients received multi-disciplinary clinical and developmental assessments. For a subtest of subjects, additional standardized
Heritability, stability, and prevalence of tonic and phasic irritability as indicators of disruptivemooddysregulationdisorder. Little is known about genetic and environmental influences on the components of disruptivemooddysregulationdisorder (DMDD), tonic irritability (i.e., irritable mood) and phasic irritability (i.e., temper outbursts). This study examined prevalence, stability
White Matter Microstructure in Pediatric Bipolar Disorder and DisruptiveMoodDysregulationDisorder. Disruptivemooddysregulationdisorder (DMDD) codifies severe, chronic irritability. Youths with bipolar disorder (BD) also present with irritability, but with an episodic course. To date, it is not clear whether aberrant white matter microstructure-a well-replicated finding in BD-can
Aripiprazole/Methylphenidate Combination in Children and Adolescents with DisruptiveMoodDysregulationDisorder and Attention-Deficit/Hyperactivity Disorder: An Open-Label Study. Disruptivemooddysregulationdisorder (DMDD) is characterized by nonepisodic irritability and has a high rate of comorbidity with attention-deficit/hyperactivity disorder (ADHD). This is the first study to explore