Eosinophiliccystitis complicated with cystitis glandularis: a case report. Eosinophiliccystitis (EC) is a rare inflammatory disease characterized by the gathering and infiltration of numerous eosinophilia (EOS) in the bladder wall. Because of Few cases of EC have been reported globally, the epidemiology of EC is not well known. We report herein the details of one very scarce case of large tumor-like eosinophiliccystitis complicated with cystitis glandularis (CG) diagnosed by biopsy. A 45-year-old Chinese man was referred to our hospital for the treatment of right lumbago and odynuria. Ultrasound examination indicated the low echo on the right portion wall and the neck of the bladder. Computed tomography showed a remarkable enhancing large mass that measured 5.0 cm × 2.3 cm located
Eosinophiliccystitis in children: A case report The aim of the present case report was to investigate the clinical features, pathological examination and treatment of eosinophiliccystitis (EC) in children. Two cases of EC were reported and reviewed from January 2016 to March 2017. Case 1 (male; 6 years old) had intermittent hematuria, frequent urination, urgent urination, difficulty
Spontaneous rupture of the urinary bladder caused by eosinophiliccystitis in a male after binge drinking: A case report. Spontaneous rupture of the urinary bladder is a rare, difficult to diagnose surgical emergency with a high mortality, there are many causes for spontaneous rupture of the urinary bladder, but we only found 2 reports on this condition in our literature search. A 36-year-old male patient was admitted with "whole abdominal pain associated with hematuria for 5 hours." Our patient did not have a history of definite allergy, but a long-term history of alcohol abuse. This patient was followed up for 1 year, and the cystoscopy recheck showed that the bladder lesion had healed. Since eosinophiliccystitis is associated with long-term alcohol consumption, we recommended
BRAF mutation as a novel driver of eosinophiliccystitisEosinophiliccystitis is a rare manifestation of hypereosinophilia and a cause of morbidity, including dysuria and hematuria. Although some cases can be attributed to infection or allergy, most cases are assessed to be idiopathic and treated with corticosteroids. However, hypereosinophilia can also be due to actionable clonal molecular the molecular features of eosinophilic disorders. We also describe the use of a liquid biopsy of circulating cell-free DNA in the workup of a case of eosinophiliccystitis in which next generation sequencing of cell-free DNA showed a BRAF I463T mutation. In silico modeling supports the functional impact and potential clinical relevance of BRAF I463T.
Eosinophiliccystitis with recurrent urinary retention: case report Eosinophiliccystitis is a rare inflammatory disease of the bladder whose origin, pathogenesis, and treatment are unknown. Frequency, dysuria, and hematuria are frequent symptoms. Here, we report a rare occurrence of recurrent urinary retention and repetitive catheterization. A 67-year-old male presented with acute urinary of the mucosa was normal. Transurethral biopsies of the lesion were performed and histologic examination showed features of eosinophiliccystitis. Despite multiple medication regimens containing corticosteroids and antihistamines, he presented with recurrent urinary retention, approximately once every month. After 6 months, he was started on bethanechol, which led to no catheterization for up to 2 years
Mass Forming EosinophilicCystitis in Pediatric Patients. Eosinophiliccystitis (EC) is an uncommon inflammatory disorder of uncertain etiology that has been described in adult and pediatric populations. We describe 3 recent cases of EC that presented as a mass lesion in pediatric patients from the New England region of the United States. All patients were initially suspected to have a malignancy
Successful use of cyclosporine as treatment for eosinophiliccystitis: a case report Eosinophiliccystitis is a rare inflammatory disorder characterized by eosinophilic infiltration of all layers of the urinary bladder wall. Due to lack of consensus and potential for side effect from various therapeutic options, treatment of the disease is often challenging. A 64-year old woman with hypertensive nephropathy resulting in stage III chronic kidney disease, obstructive sleep apnea, and obstructive lung disease presented with a 4 month history of dysuria, urgency, frequency, and persistent hematuria. Based on eosinophilic infiltration on bladder wall biopsy in the absence of any evidence of infection, malignancy, or immune disorder, she was diagnosed with eosinophiliccystitis. Despite multiple
Macroscopic Hematuria and a Bladder Mass: EosinophilicCystitis in a 7-Year-Old Boy We report a case of eosinophiliccystitis in a 7-year-old boy with a history of atopic symptoms, with focus on the radiological findings. He presented with hematuria and dysuria and ultrasonography (US) showed irregular bladder wall thickening resembling a bladder mass. CT urography did not characterize the lesion any further and showed no local or distant spread. Biopsies revealed eosinophiliccystitis, a benign inflammatory condition. We found that US characterized the lesion at least as well as CT and should be the first choice of imaging. When staging is considered before biopsy, MRI should be preferred to CT. There are no specific radiological signs of eosinophiliccystitis. On follow-up, US was a safe
Eosinophiliccystitis and haematuria: Case report of a rare disease and common presentation Eosinophiliccystitis is a rare inflammatory condition of the bladder that can cause haematuria. The aetiology is unknown and clinical presentation is difficult to distinguish from other causes of haematuria. Diagnosis is confirmed by biopsy. In this case, a patient with haematuria is diagnosed with no resolution. After further investigations including a cystoscopy and bladder biopsy, he was diagnosed with eosinophiliccystitis. He was treated with steroids improving his symptoms. Eosinophiliccystitis is a rare disease of the bladder which is difficult to distinguish from other causes of haematuria, and is often misdiagnosed. Bladder biopsy is necessary for diagnosis. Early diagnosis is important
EosinophilicCystitis: A Rare Cause of Nocturnal Enuresis in Children Eosinophiliccystitis (EC) is a rare and poorly understood inflammatory condition, characterized by eosinophilic infiltration of all layers of the bladder wall, which mimics bladder tumors. EC may present with symptoms such as increased urination frequency, dysuria, gross/microscopic hematuria, suprapubic pain and urinary
Inflammatory myofibroblastic tumor of the bladder masquerading as eosinophiliccystitis: case report and review of the literature. A 9-year-old boy presented with gross hematuria of 2 days duration. Cystoscopic evaluation revealed an anterior bladder mass. Pathology was consistent with eosinophiliccystitis, and a steroid regimen was initiated accordingly, but no improvement ensued. Concern
An unusual cause of terminal hematuria in a child: EosinophiliccystitisEosinophiliccystitis is a rare inflammatory disease of the bladder; it rarely occurs in children. Patients typically show irritative urination symptoms frequently, with a possible need for urgency, alongside dysuria, gross haematuria, suprapubic pain and painful urination. Sometimes bladder mass accumulation with the possibility of malignancy is also observed. We present an 8-year-old male patient who gained admission for terminal hematuria and discuss the management of eosinophiliccystitis.
How should eosinophiliccystitis be treated in patients with chronic granulomatous disease? Chronic granulomatous disease (CGD) is a primary immunodeficiency resulting from the absence or malfunction of oxidative mechanism in phagocytic cells. The disease is due to a mutation in one of four genes that encode subunits of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex . Affected patients experience severe infections and granuloma formation due to exuberant inflammatory responses. Some evidence suggests that eosinophiliccystitis (EC) is included in the spectrum of inflammatory manifestations. EC is an inflammatory disease, rare in childhood, which may require different, nonstandardized therapeutic approaches, ranging from antihistamines to cyclosporine. Herein we
EosinophilicCystitis Mimicking Urothelial Neoplasia We explored the potential etiology, clinical and histopathology presentation of the eosinophiliccystitis cases, clinically mimicking urothelial neoplasia. Surgical procedure and clinical outcome also evaluated. T A pooled 22 patients diagnosed with eosinophiliccystitis on microscopic examination in our hospital during four years were retrospectively studied.We explored the potential etiology, clinical and histopathology presentation of the eosinophiliccystitis cases, clinically mimicking urothelial neoplasia. Surgical procedure and clinical outcome also evaluated. Transurethral resection of the lesions were performed and pathologically examined, we re-examined the studied cases and made a clinical correlation.
Montelukast as a Successful Treatment for EosinophilicCystitis in an Asthmatic Woman Patient Eosinophiliccystitis (EC) is a rare inflammatory disorder. We herein report a case of EC in an asthmatic female patient who had a recent exacerbation with none known allergen. She was administered montelukast sodium orally for four weeks and received complete remission. This medication was successfully
; * Section 3.19 – Rare Conditions – A new section has been added to the section on bladder tumours on eosinophiliccystitis and nephrogenic adenoma.3.19Recommendations for rare conditions in children3.19.2Papillary tumours of the bladder in children and adolescents - Eosinophiliccystitis and Nephrogenic adenoma3.19.2.9 Recommendations for papillary tumours of the bladder in childrenRecommendations LE Strength rating Have a high index of suspicion of eosinophiliccystitis (EC) in protracted urinary tract symptoms unresponsive to regular treatment. 4 Strong Remove any possible allergens as the obvious first step in managing EC. 4 Strong Eosinophiliccystitis can
; * Section 3.19 – Rare Conditions – A new section has been added to the section on bladder tumours on eosinophiliccystitis and nephrogenic adenoma.3.19Recommendations for rare conditions in children3.19.2Papillary tumours of the bladder in children and adolescents - Eosinophiliccystitis and Nephrogenic adenoma3.19.2.9 Recommendations for papillary tumours of the bladder in childrenRecommendations LE Strength rating Have a high index of suspicion of eosinophiliccystitis (EC) in protracted urinary tract symptoms unresponsive to regular treatment. 4 Strong Remove any possible allergens as the obvious first step in managing EC. 4 Strong Eosinophiliccystitis can