Altered asymmetry of amygdala volume mediates foodaddiction and weight gain. Foodaddiction and an impulsive personality can increase overeating, which can lead to weight gain. The amygdala and nucleus accumbens (NAcc) are critical for regulating obesogenic behaviour. However, whether the amygdala or the NAcc acts as the neural basis for the regulation of foodaddiction, impulsive personality the LIs of brain regions, impulsive personality, foodaddiction, and BMI through a multiple chain mediation model. We observed a significant decrease in the LI of the amygdala in the obese group compared with the healthy group (F = 20.276, p < 0.001), which indicates that the right amygdala was larger than the left amygdala in the obese group. Network analysis revealed that the LI of the amygdala
Associations of foodaddiction symptomatology with bariatric surgical attrition: a cross-sectional analysis. Despite the effectiveness of bariatric surgery, there remains a high rate of attrition from surgical programs, highlighting the need to understand factors that influence presurgical attrition rates. To investigate the association between foodaddiction (FA) symptomatology and attrition
Bidirectional mediation of psychological distress and foodaddiction influenced by childhood trauma among adolescents. This study aims to explore the relationship between childhood trauma, psychological distress, and foodaddiction in adolescents. The sample comprised 4560 adolescents (46.67 % females) aged 12-19 years (15.21 ± 1.75) who participated in the School-based Evaluation Advancing Response for Child Health (SEARCH) survey, a mixed longitudinal cohort study in Jiangsu, China. Bidirectional mediation was used to assess the interplay among childhood trauma, psychological distress, and foodaddiction derived from a self-report survey. Among participants, 29.67 % reported experiencing at least one type of trauma during childhood, and 2.80 % exhibited significant symptoms of food
Social, clinical, and policy implications of ultra-processed foodaddiction. Conceptualising ultra-processed foods high in carbohydrates and fats as addictive substances can contribute to efforts to improve health, argue
Brazilian Version of the Yale FoodAddiction Scale for Individuals with Severe Obesity. Adapting and validating the Portuguese version of Br-YFAS 2.0-Obes to allow it to be used by the Brazilian candidates for bariatric surgery. This study included 329 individuals with body mass indexes (BMI) ≥ 30 kg/m, candidates for bariatric surgery at a reference hospital in Brazil. They were given
The effectiveness of the TRACE online nutrition intervention in improving dietary intake, sleep quality and physical activity levels for Australian adults with foodaddiction: a randomised controlled trial. Few interventions for foodaddiction (FA) report on dietary intake variables. The present study comprised a three-arm randomised controlled trial in adults with symptoms of FA. The aim
Using latent class analysis to identify different clinical profiles according to foodaddiction symptoms in obesity with and without binge eating disorder. Existing research suggests that foodaddiction (FA) is associated with binge eating disorder (BED) and obesity, but the clinical significance of this relationship remains unclear. This study aims to investigate the different clinical profiles
Effects of Probiotic Supplementation Added to a Weight Loss Program on Anthropometric Measures, Body Composition, Eating Behavior, and Related Hormone Levels in Patients with FoodAddiction and Weight Regain After Bariatric Surgery: A Randomized Clinical Weight regain after metabolic bariatric surgery is a common problem. Foodaddiction is an eating disorder that can be one of the reasons for weight regain in these patients. This study aimed to evaluate the effects of probiotic supplementation with a weight loss program and cognitive behavioral therapy (CBT) on anthropometric measures, eating behavior, foodaddiction, and related hormone levels, in patients with foodaddiction and weight regain after metabolic bariatric surgery. This randomized, triple-blind, placebo-controlled clinical
Gut microbiota signatures of vulnerability to foodaddiction in mice and humans. Foodaddiction is a multifactorial disorder characterised by a loss of control over food intake that may promote obesity and alter gut microbiota composition. We have investigated the potential involvement of the gut microbiota in the mechanisms underlying foodaddiction. We used the Yale FoodAddiction Scale (YFAS ) 2.0 criteria to classify extreme foodaddiction in mouse and human subpopulations to identify gut microbiota signatures associated with vulnerability to this disorder. Both animal and human cohorts showed important similarities in the gut microbiota signatures linked to foodaddiction. The signatures suggested possible non-beneficial effects of bacteria belonging to the Proteobacteria phylum
The Presence of FoodAddiction in Patients with Binge Eating Disorder Was Associated with Higher Weight, Poor Body Composition Outcomes, Lower Serum Level of Magnesium and Higher Ferritin 2 Years Post-LSG Surgery. This study examined the presence of foodaddiction (FA) in patients with binge eating disorder (BED) 2 years after laparoscopic sleeve gastrectomy (LSG) and explored its association with some minerals, ferritin, weight loss and, body composition outcomes. In this study, 120 patients with BED who had undergone LSG 2 years prior to participation were enrolled. BED was assessed using Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) criteria and presence of FA was assessed using the Yale FoodAddiction Scale (YFAS). The collected data included general
Effects of probiotic supplementation with weight reducing intervention on anthropometric measures, body composition, eating behavior, and related hormone levels in patients with foodaddiction and weight regain after bariatric surgery: a study protocol f One of the unfortunate events after bariatric surgery is the weight regain, which occurs in some patients. Foodaddiction is an eating disorder related to the brain-intestinal axis and can be effective in weight regain after bariatric surgery. In addition, the gut microbiome plays a vital role in eating behaviors, including foodaddiction. So, this study will aim to evaluate the effects of probiotic supplementation with a weight-reducing diet and cognitive behavioral therapy on anthropometric measures, body composition, eating behavior
Effect of time restricted feeding on anthropometric measures, eating behavior, stress, serum levels of BDNF and LBP in overweight/obese women with foodaddiction: a randomized clinical trial. Foodaddiction (FA) as a specific food-related behavior may play an essential role in the pathogenesis of obesity. Brain-derived neurotrophic factor (BDNF) and gut microbiota (GM) alterations probably ( = 0.018, = 0.015. = 0.03, and = 0.036, respectively). The cognitive restriction score was higher in the TRF as compared with the control group ( = 0.002). The foodaddiction criteria score was significantly reduced in both groups ( < 0.001). Serum levels of BDNF were significantly increased in the TRF group ( < 0.001). In addition, BDNF levels had a positive and significant correlation
Prevalence and Correlates of FoodAddiction in Bariatric Surgery Candidates and Its Effect on Bariatric Surgery Outcome: A Prospective Observational Study. Studies have shown a high prevalence of foodaddiction (FA) in bariatric surgery candidates. This study examines prevalence of FA prior to and one year after bariatric surgery and the determinants of preoperative FA. Additionally, this study investigates how preoperative variables affect excess weight loss (EWL) one year after bariatric surgery. This prospective observational study included 102 patients at an obesity surgery clinic. Self-report measures, including demographic characteristics, the Yale FoodAddiction Scale 2.0 (YFAS 2.0), the Depression Anxiety Stress Scale (DASS-21), and the Dutch Eating Behavior Questionnaire (DEBQ) were used
Group therapy to reduce maladaptive eating behaviors in people with overweight or obesity: Does foodaddiction impact the treatment response? Given that the presence of foodaddiction worsens the clinical portrait in people with overweight or obesity, it could also impact the treatment response. The objective was to explore the moderating effect of baseline foodaddiction (FA) on the treatment
Plasma concentration of leptin is related to foodaddiction in gambling disorder: Clinical and neuropsychological implications. Data implicate overlaps in neurobiological pathways involved in appetite regulation and addictive disorders. Despite different neuroendocrine measures having been associated with both gambling disorder (GD) and foodaddiction (FA), how appetite-regulating hormones may included 297 patients diagnosed with GD (93.6% males). None of the patients with GD had lifetime diagnosis of an eating disorder. FA was evaluated with the Yale FoodAddiction Scale 2.0. All patients were assessed through a semi-structured clinical interview and a psychometric battery including neuropsychological tasks. Blood samples to measure hormonal variables and anthropometric variables were also
Foodaddiction and lifetime alcohol and illicit drugs use in specific eating disorders. Foodaddiction (FA) and substance use (SU) have frequently been reported in patients with eating disorders (EDs). Our study aimed to assess the prevalence rates of FA and/or lifetime problematic alcohol and illicit drug use among patients with specific ED, such as: bulimia nervosa (BN), binge eating disorder (BED), and other specified feeding and eating disorder (OSFED). We sought to identify clinical, psychopathological, and personality profiles involved in these addictive behavior-based phenotypes. The total sample was 527 patients (176 BN, 115 BED, and 236 OSFED). FA was assessed through the Yale FoodAddiction Scale 2.0. To determine lifetime SU, a semi-structured clinical interview was carried out
Examining how framing obesity as disease vs. foodaddiction influences stigma among fitness practitioners. To determine if framing the etiology of obesity as a disease, foodaddiction, or caloric imbalance would increase or decrease anti-fat attitudes (AFA) and challenge the belief that obesity is caused by a lack of personal responsibility or willpower. Two hundred and forty-nine fitness practitioners (M = 37.49 years) were randomly assigned to one of four experimental conditions and asked to read a short article describing obesity as either: (a) foodaddiction, (b) disease, or (c) caloric imbalance, while a control group read an unrelated article. All practitioners then completed a measure of AFA. Practitioners in the foodaddiction condition recorded significantly lower AFA than
PROBIOTIC SUPPLEMENTATION ATTENUATES BINGE EATING AND FOODADDICTION 1 YEAR AFTER ROUX-EN-Y GASTRIC BYPASS: A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL. The use of probiotics as adjuvants in the treatment of eating disorders, known as psychobiotics, has already been investigated as a means of modulating the microbiota-gut-brain axis. This study aimed to assess the effect of probiotic supplementation on binge eating and foodaddiction in subjects after Roux-en-Y gastric bypass surgery. This is a randomized, double-blind, placebo-controlled trial involving 101 patients who received probiotic (Lactobacillus acidophilus NCFM and Bifidobacterium lactis Bi-07) or placebo supplements for 90 days after bariatric surgery, starting on the seventh postoperative day. They were evaluated preoperatively
The combined effects of probiotics and restricted calorie diet on the anthropometric indices, eating behavior, and hormone levels of obese women with foodaddiction: a randomized clinical trial. Foodaddiction (FA) is an important contributor to obesity. Alterations in gut microbiota (GM) diversity and composition have also been proposed to play a pivotal role in obesity pathogenesis. This trial
Effect of time restricted feeding on anthropometric measures, eating behavior, stress, and brain-derived neurotrophic factor (BDNF) and lipopolysaccharide-binding protein (LBP) levels in women with overweight/obesity and foodaddiction: a study protocol Foodaddiction is one of the behavioral factors that play an important role in the pathogenesis of obesity. Much evidence is available suggesting intestinal microbiomes can play a role in eating behavior, body composition, and BDNF levels, and they can be modified by time-restricted feeding (TRF). So, this study will aim to evaluate the effect of TRF on anthropometric measures, eating behavior, stress, and serum BDNF and LBP levels in women with overweight/obesity and foodaddiction. We will carry out a randomized clinical trial for 8