Clinical features of Haffdisease and myositis after the consumption of boiled brackish water crayfish: a retrospective study of 96 cases at a single centre. The present study describes the difference in clinical features between the patients with Haffdisease and crayfish-related myositis (CRM) after crayfish consumption. This was a single-centre, retrospective analysis at the Emergency Department of the Drum Tower Hospital of Nanjing University School of Medicine from July to August of 2016. The baseline information came from the Electronic Medical Record System at the institution. Totally 96 patients were included, of whom 52 patients were confirmed to have Haffdisease and 44 patients were CRM. The illness predominately occurs in summer and most of them (55/96) are female. The primary
Clinical and laboratory evidence of Haffdisease - case series from an outbreak in Salvador, Brazil, December 2016 to April 2017. We describe a series of 15 Haffdisease cases from an outbreak in Salvador, Brazil, starting early December 2016. Eleven cases were grouped in four family clusters of two to four individuals, four were isolated cases. All but one patient consumed cooked fish; 11 within
Two Cases of Rhabdomyolysis (HaffDisease) After Eating Carp Fish Unexplained rhabdomyolysis after eating fish is a rare condition caused by an unidentified toxin. Most of the incidences in the United States have been linked to consuming buffalo fish or crawfish. We present 2 cases of Haffdisease in which the patients consumed grass carp as opposed to the usual suspects of buffalo fish
The Emergence and Epidemiology of HaffDisease in China Haffdisease is a rare syndrome of unexplained myalgia and rhabdomyolysis occurring within 24 h of consumption of certain types of cooked freshwater fish or crustacean. It is caused by a yet unidentified heat-stable toxin. In the present review of published case studies and official press releases, the main objective is to report the emergence and epidemiology of Haffdisease in China. Haffdisease first occurred in Beijing in 2000 and in Lianzhou and Liannan, Guangdong Province in 2009. Subsequent outbreaks mostly occurred in the Jiangsu Province-Nanjing, Yangzhou, Huai'an, and Yancheng. Isolated outbreaks occurred in other cities since 2010-Shijiazhuang, Yueyang, Shanghai, Wuhu, Baoding, Shenzhen, and Hong Kong (imported cases from
Rhabdomyolysis After Cooked Seafood Consumption (HaffDisease) in the United States vs China Haffdisease is a syndrome of myalgia and rhabdomyolysis that occurs after eating cooked seafood. For this descriptive analytical article, a literature search identified the scientific articles on Haffdisease and/or rhabdomyolysis after eating cooked seafood in the United States and China. Analysis of those articles focused on identifying the seafood vectors of Haffdisease, describing the most commonly recurring clinical and laboratory manifestations of Haffdisease, and comparing the Haffdisease toxidrome with other similar seafood-borne toxidromes. Statistically significant differences were determined using unpaired t tests and Fisher exact tests. Twenty-nine confirmed cases of Haffdisease
HaffDisease: Rhabdomyolysis After Eating Buffalo Fish Haffdisease, rhabdomyolysis after ingesting certain types of fish, was first reported in 1924 in Europe. There have been a limited number of cases reported in the United States. We present the case of a patient who presents with symptoms of rhabdomyolysis after eating cooked buffalo fish purchased at a suburban grocery market.
A past Haffdisease outbreak associated with eating freshwater pomfret in South China. Haffdisease is unexplained rhabdomyolysis caused by consumption of fishery products in the previous 24 h. It was first identified in Europe in 1924 but the condition is extremely rare in China. Here we describe a past outbreak of acute food borne muscle poisoning that occurred in Guangdong Province (South China) in 2009. The first full outbreak of Haffdisease reported in Jiangsu Province (East China) in 2010, indicated that the incidence of the disease may be increasing in China. We, therefore first retrospectively reviewed epidemiologic, trace-back, environmental studies, and laboratory analyses, including oral toxicity testing to ascertain risk and chemical analysis to identify toxin(s), from
Case Series: Inhaled Coral Vapor—Toxicity in a Tank Palytoxin (PTX) is considered a severe marine toxin. Although rare, reports of human exposure from consumption of PTX have described significant morbidity and mortality. PTX is the suspected agent in Haffdisease, in which rhabdomyolysis occurs within 24 h of eating contaminated fish such as buffalo fish. PTX is primarily present in soft
Haffdisease: from the Baltic Sea to the U.S. shore. Haffdisease, identified in Europe in 1924, is unexplained rhabdomyolysis in a person who ate fish in the 24 hours before onset of illness. We describe a series of six U.S. patients from 1997 and report new epidemiologic and etiologic aspects. Although Haffdisease is traditionally an epidemic foodborne illness, these six cases occurred in two
Efficacy of Active Charcoal and Mannitol in Patients with HaffDisease Caused by the Consumption of Crayfish (Procambarus clarkii): A Retrospective Cohort Study. This study evaluates the clinical efficacy of activated charcoal combined with mannitol (ACM) for the treatment of Haffdisease. This is a retrospective cohort study conducted at the Emergency Department of Affiliated Hospital of Integrated Traditional Chinese and Western Medicine. Consecutive patients who were hospitalized during a two-year time frame (from June 2016 to August 2017) and diagnosed with Haffdisease were reviewed. Clinical symptoms, laboratory findings, pain/anxiety scores, and treatment-related adverse events were collected. Sixty-eight Haffdisease patients after boiled crayfish consumption were enrolled