"Intracerebral hemorrhage"

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                            1
                            2023BMJ Best Practice
                            Stroke due to spontaneous intracerebral haemorrhage Skip to main contentSkip to searchLog inEnglish#{autosuggest.search}#{autosuggest.search}Stroke due to spontaneous intracerebral haemorrhageVer contenido en español MENULog in or subscribe to access all of BMJ Best PracticeLast reviewed:1 Oct 2023Last updated:27 Oct 2023SummaryStroke due to spontaneous intracerebral haemorrhage (ICH thrombosis is a rare form of stroke that occurs due to thrombosis of the dural venous sinuses.Most intracerebral haemorrhages occur in the absence of vascular malformations, aneurysms, or other structural causes, and are presumed to be due to diseases affecting small cerebral vessels (arteriolosclerosis or cerebral amyloid angiopathy); this is often called primary intracerebral haemorrhage (ICH
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                            2025Neurocritical Care Society
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                            of epileptic seizures in the acute phase of intracerebral haemorrhage (PEACH): a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Neurol. 2022;21(9):781–91. Article CAS PubMed Google Scholar 2. Vespa PM, O’Phelan K, Shah M, Mirabelli J, Starkman S, Kidwell C, et al. Acute seizures after intracerebral hemorrhage: a factor in progressive midline shift and outcome. Neurology. 2003;60(9):1441 Guidelines for Seizure Prophylaxis in Patients Hospitalized with Nontraumatic Intracerebral Hemorrhage: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society Guidelines for Seizure Prophylaxis in Patients Hospitalized with Nontraumatic Intracerebral Hemorrhage: A Clinical Practice Guideline for Health Care Professionals from the Neurocritical Care Society
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                            In patients with spontaneous intracerebral hemorrhage, does tranexamic acid (TXA) given within 2 hours of symptom onset, as compared with placebo (saline solution), decrease hematoma expansion? www.annemergmed.comVerify you are human by completing the action below.www.annemergmed.com needs to review the security of your connection before proceeding.Ray ID: 8a52ea0bd87f9403Performance & security
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                            2024American Heart Association
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                            AHA/ASA Performance and Quality Measures for Spontaneous Intracerebral Hemorrhage: A Report From the American Heart Association/American Stroke Association www.ahajournals.orgVerify you are human by completing the action below.www.ahajournals.org needs to review the security of your connection before proceeding.Ray ID: 888d944bbbdb653ePerformance & security by Cloudflare
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                            2023Neurocritical Care Society
                            Trip Score
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                            Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage Your privacy, your choiceWe use essential cookies to make sure the site can function. We also use optional cookies for advertising, personalisation of content, usage analysis, and social media.By accepting optional cookies, you consent to the processing of your personal data - including transfers to third associated with intracerebral hemorrhage (ICH) neuroprognostication.MethodsA narrative systematic review was completed using the Grading of Recommendations Assessment, Development, and Evaluation methodology and the Population, Intervention, Comparator, Outcome, Timing, Setting questions. Predictors, which included both individual clinical variables and prediction models, were selected based on clinical
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                            2022theNNT
                            control and clinical outcomes in acute intracerebral haemorrhage: a preplanned pooled analysis of individual participant data. Lancet Neurol. 2019;18(9):857-864.Anderson CS, Heeley E, Huang Y, et al. INTERACT2 investigators. Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. N Engl J Med. 2013;368(25):2355-2365.Qureshi AI, Palesch YY, Barsan WG, et al. ATACH-2 trial intracerebral haemorrhage: a systematic review and meta-analysis of individual patient data. J Neurol Neurosurg Psychiatry. 2022;93(1):6-13.Gong S, Lin C, Zhang D, et al. Effects of intensive blood pressure reduction on acute intracerebral hemorrhage: a systematic review and meta-analysis. Sci Rep. 2017;7(1):10694.SHARE ONOTHER EBM RESOURCESMDCalcTrip DatabaseBMJ Evidence UpdatesJAMAEvidence - The Rational
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                            2022American Heart Association
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                            Narrative based
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                            2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association 2022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association | Stroke Advertisement * Science Volunteer * Warning signs * Author Reprints * This site uses cookies. By continuing to browse this site you are agreeing to our use of cookies.Click here for more information.× HomeStrokeVol. 53, No. 72022 Guideline for the Management of Patients With Spontaneous Intracerebral Hemorrhage: A Guideline From the American Heart Association/American Stroke Association Free AccessReview ArticlePDF/EPUB * About * View PDF
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                            2022Chinese Clinical Guidelines
                            Chinese multidisciplinary guideline for management of hypertensive intracerebral hemorrhage Chinese multidisciplinary guideline for management of hypertensive intracerebral hemorrhage : Chinese Medical Journal Log inorRegister Get new issue alertsSecondary LogoJournal LogoArticlesAdvanced SearchHistoryHomeArticles CollectionsFor ReadersReviewersFor AuthorsSubscribeMultimediaJournal Info Previous : 10.1097/CM9.0000000000001976OPENSDCPAP MetricsHypertensive intracerebral hemorrhage (HICH) refers to the sudden onset of hemorrhage within cerebral parenchyma or ventricles of patients with a history of hypertension. Secondary intracerebral hemorrhage (ICH) with an underlying causative pathology, such as trauma, structural blood vessel abnormalities, coagulation or hematological disorder(s), systemic
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                            2025PLoS ONE
                            A novel prediction method for intracerebral hemorrhage-associated pneumonia: A single center analysis. Stroke-associated pneumonia (SAP) is a common complication leading to death and disability after a stroke. Currently, more studies tend to focus on stroke-associated pneumonia in patients with ischemic stroke, while there are few studies on predictors of intracerebral hemorrhage-associated pneumonia (ICHAP). It is necessary to discover new predictors to build more accurate prediction models for ICHAP. We continuously collected 498 patients with acute intracerebral hemorrhage and then divided them into ICHAP and non-ICHAP groups. Then we conducted univariate analyses and multivariate regression analyses on the collected data. Afterward, the new predictors of ICHAP were found
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                            2025Lancet
                            Direct oral anticoagulants versus no anticoagulation for the prevention of stroke in survivors of intracerebral haemorrhage with atrial fibrillation (PRESTIGE-AF): a multicentre, open-label, randomised, phase 3 trial. Direct oral anticoagulants (DOACs) reduce the rate of thromboembolism in patients with atrial fibrillation but the benefits and risks in survivors of intracerebral haemorrhage are uncertain. We aimed to determine whether DOACs reduce the risk of ischaemic stroke without substantially increasing the risk of recurrent intracerebral haemorrhage. PRESTIGE-AF is a multicentre, open-label, randomised, phase 3 trial conducted at 75 hospitals in six European countries. Eligible patients were aged 18 years or older with spontaneous intracerebral haemorrhage, atrial fibrillation
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                            2020Canadian Stroke Best Practices
                            Canadian stroke best practice recommendations: Management of Spontaneous Intracerebral Hemorrhage, 7th Edition Update 2020 journals.sagepub.comChecking if the site connection is securejournals.sagepub.com needs to review the security of your connection before proceeding.Ray ID: 8354ec500bfadcbbPerformance & security by Cloudflare
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                            2024PLoS ONE
                            Ultrasound combined with urokinase under key-shaped bone window enhances blood clot lysis in an in vitro model of spontaneous intracerebral hemorrhage. Minimally invasive surgery for spontaneous intracerebral hemorrhage is impeded by inadequate lysis of the target blood clot. Ultrasound is thought to expedite intravascular thrombolysis, thereby facilitating vascular recanalization. However , the impact of ultrasound on intracerebral blood clot lysis remains uncertain. This study aimed to explore the feasibility of combining ultrasound with urokinase to enhance blood clot lysis in an in vitro model of spontaneous intracerebral hemorrhage. The blood clots were divided into four groups: control group, ultrasound group, urokinase group, and ultrasound + urokinase group. Using our experimental
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                            2024EvidenceUpdates
                            Effects of an early intensive blood pressure-lowering strategy using remifentanil and dexmedetomidine in patients with spontaneous intracerebral hemorrhage: a multicenter, prospective, superiority, randomized controlled trial Although it has been established that elevated blood pressure and its variability worsen outcomes in spontaneous intracerebral hemorrhage, antihypertensives use during intracerebral hemorrhage. In this multicenter, prospective, single-blinded, superiority randomized controlled trial, patients with intracerebral hemorrhage and systolic blood pressure (SBP) ≥150 mmHg were randomly allocated to the intervention group (a preset protocol with a standard guideline management using remifentanil and dexmedetomidine) or the control group (standard guideline-based management
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                            2024EvidenceUpdates
                            Tranexamic acid versus placebo in individuals with intracerebral haemorrhage treated within 2 h of symptom onset (STOP-MSU): an international, double-blind, randomised, phase 2 trial Tranexamic acid, an antifibrinolytic agent, might attenuate haematoma growth after an intracerebral haemorrhage. We aimed to determine whether treatment with intravenous tranexamic acid within 2 h of an intracerebral haemorrhage would reduce haematoma growth compared with placebo. STOP-MSU was an investigator-led, double-blind, randomised, phase 2 trial conducted at 24 hospitals and one mobile stroke unit in Australia, Finland, New Zealand, Taiwan, and Viet Nam. Eligible participants had acute spontaneous intracerebral haemorrhage confirmed on non-contrast CT, were aged 18 years or older, and could
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                            2024NEJM
                            Andexanet for Factor Xa Inhibitor-Associated Acute Intracerebral Hemorrhage. Patients with acute intracerebral hemorrhage who are receiving factor Xa inhibitors have a risk of hematoma expansion. The effect of andexanet alfa, an agent that reverses the effects of factor Xa inhibitors, on hematoma volume expansion has not been well studied. We randomly assigned, in a 1:1 ratio, patients who had taken factor Xa inhibitors within 15 hours before having an acute intracerebral hemorrhage to receive andexanet or usual care. The primary end point was hemostatic efficacy, defined by expansion of the hematoma volume by 35% or less at 12 hours after baseline, an increase in the score on the National Institutes of Health Stroke Scale of less than 7 points (scores range from 0 to 42, with higher scores
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                            2024Lancet
                            Decompressive craniectomy plus best medical treatment versus best medical treatment alone for spontaneous severe deep supratentorial intracerebral haemorrhage: a randomised controlled clinical trial. It is unknown whether decompressive craniectomy improves clinical outcome for people with spontaneous severe deep intracerebral haemorrhage. The SWITCH trial aimed to assess whether decompressive craniectomy plus best medical treatment in these patients improves outcome at 6 months compared to best medical treatment alone. In this multicentre, randomised, open-label, assessor-blinded trial conducted in 42 stroke centres in Austria, Belgium, Finland, France, Germany, the Netherlands, Spain, Sweden, and Switzerland, adults (18-75 years) with a severe intracerebral haemorrhage involving the basal
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                            2024NEJM
                            Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage. Trials of surgical evacuation of supratentorial intracerebral hemorrhages have generally shown no functional benefit. Whether early minimally invasive surgical removal would result in better outcomes than medical management is not known. In this multicenter, randomized trial involving patients with an acute intracerebral , -0.147 to 0.116) among those with anterior basal ganglia hemorrhages. The percentage of patients who had died by 30 days was 9.3% in the surgery group and 18.0% in the control group. Five patients (3.3%) in the surgery group had postoperative rebleeding and neurologic deterioration. Among patients in whom surgery could be performed within 24 hours after an acute intracerebral hemorrhage, minimally
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                            2024PLoS ONE
                            Prognostic biomarkers of intracerebral hemorrhage identified using targeted proteomics and machine learning algorithms. Early prognostication of patient outcomes in intracerebral hemorrhage (ICH) is critical for patient care. We aim to investigate protein biomarkers' role in prognosticating outcomes in ICH patients. We assessed 22 protein biomarkers using targeted proteomics in serum samples
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                            2024PLoS ONE
                            Machine learning-based pipeline for automated intracerebral hemorrhage and drain detection, quantification, and classification in non-enhanced CT images (NeuroDrAIn). External drainage represents a well-established treatment option for acute intracerebral hemorrhage. The current standard of practice includes post-operative computer tomography imaging, which is subjectively evaluated . The implementation of an objective, automated evaluation of postoperative studies may enhance diagnostic accuracy and facilitate the scaling of research projects. The objective is to develop and validate a fully automated pipeline for intracerebral hemorrhage and drain detection, quantification of intracerebral hemorrhage coverage, and detection of malpositioned drains. In this retrospective study, we selected
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                            2024Lancet
                            Traditional Chinese medicine FYTF-919 (Zhongfeng Xingnao oral prescription) for the treatment of acute intracerebral haemorrhage: a multicentre, randomised, placebo-controlled, double-blind, clinical trial. There are few proven treatments for acute spontaneous intracerebral haemorrhage, and they all target reducing expansion of the haematoma. The traditional Chinese medicine FYTF-919 (Zhongfeng Xingnao) in an oral solution is comprised of several Chinese herbs that are widely used to treat patients with intracerebral haemorrhage in China on the understanding that they enhance resorption of the haematoma and reduce neuroinflammation. We aimed to provide a reliable assessment of the safety and efficacy of FYTF-919 in patients with moderate to severe acute intracerebral haemorrhage. We did