"Ketoacidosis"

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                            Is Subcutaneous Insulin Administration Safe and Effective for the Treatment of Mild to Moderate Diabetic Ketoacidosis? www.annemergmed.com Verify you are human by completing the action below. www.annemergmed.com needs to review the security of your connection before proceeding.Ray ID: 921cc1c8ca3b71b4Performance & security by Cloudflare
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                            2024BMJ Best Practice
                            Diabetic ketoacidosis Skip to main contentSkip to searchEnglish (US)EnglishPortuguês中文Log inSearchSearchHomeDiabetic ketoacidosisVer contenido en español MENUThis topic is available for freeLast reviewed:1 Apr 2024Last updated:22 Apr 2024SummaryDiabetic ketoacidosis (DKA) is characterised by a biochemical triad of hyperglycaemia (or a history of diabetes), ketonaemia, and metabolic acidosis for successful treatment. It is characterised by absolute or relative insulin deficiency and is the most common acute hyperglycaemic complication of type 1 diabetes mellitus.[1][2][Figure caption and citation for the preceding image starts]:Triad of DKAAdapted with permission from Kitabchi AE, Wall BM. Diabetic ketoacidosis. Med Clin North Am. 1995;79:9-37.[Citation ends].This topic covers diabetic
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                            2022Canadian Paediatric Society
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                            Current recommendations for management of paediatric diabetic ketoacidosis Skip to ContentA home for paediatricians. A voice for children and youth.PRACTICE POINT138SharesCurrent recommendations for management of paediatric diabetic ketoacidosisPosted: Dec 5, 2022The Canadian Paediatric Society gives permission to print single copies of this document from our website. For permission to reprint or reproduce multiple copies, please see our copyright policy.Principal author(s)Karen Gripp, Evelyne D. Trottier, Sidd Thakore, Jonathan Sniderman, Sarah Lawrence; Canadian Paediatric Society, Acute Care CommitteeAbstractTreatment of paediatric diabetic ketoacidosis (DKA) includes careful attention to fluids and electrolytes to minimize the risk of complications such as cerebral injury (CI), which
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                            2023Queensland paediatric emergency clinical guidelines
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                            Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycaemic State (HHS) ' Emergency management in children Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycaemic State (HHS) – Emergency management in children | Children's Health Queensland Skip to main content Skip to main navigation health.qld.gov.au Contact Us Search Menu Queensland Government Children's Health Queensland Search ) * Queensland paediatric clinical guidelines * Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycaemic State (HHS) Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycaemic State (HHS) – Emergency management in childrenOn this page View resources * Emergency management flowchart [PDF 601.29 KB] - 1 page * Ongoing management flowchart [PDF 487.79 KB] - 1 page * DKA fluid calculator (desktop only) [XLSX
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                            Diabetic Ketoacidosis Printed copies of this document may not be up to date, obtain the most recent version from www.cats.nhs.uk Children’s Acute Transport Service provides paediatric intensive care retrieval for Great Ormond Street, The Royal Brompton and St Mary’s NHS Trusts. Funded and accountable to the North Thames Paediatric Intensive Care Commissioning Group through Great Ormond Street NHS Trust. Page 1 of 8 Children’s Acute Transport Service Clinical Guidelines Diabetic Ketoacidosis Document Control Information Author C Fraser-Bhalla M O’Connor Author Position CATS ANP CATS Consultant Document Owner M Clement Document Owner Position CATS Operational and Nursing Lead Document Version Version 5 Replaces Version Version 4 – January 2020
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                            2022theNNT
                            Liberal versus Conservative Intravenous Fluid Administration in Pediatric Diabetic Ketoacidosis HomeReviewsTherapy (NNT) ReviewsDiagnosis (LR) ReviewsAboutThe NNT, ExplainedThe NNT Rating SystemtheNNT Editorial ProcessThe NNT Intervention QuizAbout theNNT TeamSubmit an articleAccountLoginSign upContactDONATELiberal versus Conservative Intravenous Fluid Administration in Pediatric Diabetic KetoacidosisNo difference in GCS reduction, cerebral edema, or hospital length of stayBenefits in NNTNone were helpedHarms in NNTNone were harmedView As: NNT %SourceLong B, Gottlieb M. Liberal versus conservative intravenous fluid administration in pediatric diabetic ketoacidosis. Academic Emergency Medicine. Published online November 3, 2022:acem.14596.Study Population: Three trials of 1323 children aged 0–18
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                            2025PLoS ONE
                            Pediatric Diabetic Ketoacidosis (PDKA) among newly diagnosed diabetic patients at Dilla University Hospital, Dilla, Ethiopia: Prevalence and predictors. Diabetic ketoacidosis (DKA) is a morbid complication of Type 1 diabetes mellitus(T1DM), and its occurrence at diagnosis has rarely been studied in Ethiopia, despite the many cases seen in the pediatric population. The aim of this study presentation of DM. A high number of children present with diabetic ketoacidosis (DKA) at the initial diagnosis of diabetes mellitus (DM), which is associated with inadequate knowledge of the signs and symptoms of DM as well as the masking effect of concomitant infections in these children. Healthcare professionals should endeavor to suspect and screen children. Continuous awareness creation of DM
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                            2025PLoS ONE
                            Identification of early predictors and model for bacterial infection in diabetic ketoacidosis patients: A retrospective study. The purpose of this report was to identify effective indicators capable of predicting bacterial infection during the early stages of diabetic ketoacidosis (DKA) and to establish a diagnostic model suitable for clinical application. This was a retrospective cross
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                            2025PLoS ONE
                            Prevalence and associated factors of diabetic ketoacidosis among patients with diabetes mellitus at the University of Gondar Comprehensive and Specialized Referral Hospital Northwest, Ethiopia. Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Diabetic ketoacidosis is one of the life-threatening complications in diabetic individuals with, high morbidity and mortality globally. However, the data related to the prevalence and associated factors of diabetic ketoacidosis are limited in the study setting. To assess the prevalence of diabetic ketoacidosis and its associated factors among diabetic mellitus patients at the University of Gondar Comprehensive Specialized Hospital. A hospital-based cross
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                            2025PLoS ONE
                            Diabetic ketoacidosis and hyperglycemic hyperosmolar state are associated with higher in-hospital mortality and morbidity in diabetes patients hospitalized with ST-elevation myocardial infarction, but not within 30 days of readmission. While the cardiovascular risk of hyperglycemia has been thoroughly elucidated in patients with type 2 diabetes (T2DM) hospitalized for myocardial infarction , the evidence surrounding acute severe hyperglycemia is less well-established. Our study aimed to explore the impact of diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar state (HHS), both severe hyperglycemic conditions, on cardiovascular outcomes in patients with T2D admitted for ST-elevation myocardial infarction (STEMI). We used the National Readmission Database (2016-2019) to extract patients
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                            2025EvidenceUpdates
                            Hybrid closed-loop insulin therapy and risk of severe hypoglycaemia and diabetic ketoacidosis in young people (aged 2-20 years) with type 1 diabetes: a population-based study The effect of closed-loop insulin delivery on the risk of acute diabetes complications in people with type 1 diabetes is unclear. We investigated whether the rates of severe hypoglycaemia and diabetic ketoacidosis are lower , with diabetes duration of more than 1 year, and were treated between Jan 1, 2021, and Dec 31, 2023. The primary outcomes were the rates of severe hypoglycaemia and ketoacidosis in people using closed-loop therapy versus open-loop therapy. Key secondary outcomes were differences in HbA levels, percentage of time in glucose range of 3·9-10·0 mmol/L, and glycaemic variability. To account for relevant confounders
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                            2024EvidenceUpdates
                            Liver, renal, genitourinary and diabetic ketoacidosis risks among new users of empagliflozin versus dipeptidyl peptidase-4 inhibitors in patients with type 2 diabetes: Post-authorization safety study based on multinational cohorts To estimate risks of diabetic ketoacidosis (DKA), acute liver injury (ALI), acute kidney injury (AKI), chronic kidney disease (CKD), severe complications of urinary
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                            2020theNNT
                            Subcutaneous Rapid-Acting Insulin Analogs for Diabetic Ketoacidosis HomeReviewsTherapy (NNT) ReviewsDiagnosis (LR) ReviewsAboutThe NNT, ExplainedThe NNT Rating SystemtheNNT Editorial ProcessThe NNT Intervention QuizAbout theNNT TeamSubmit an articleAccountLoginSign upContactDONATESubcutaneous Rapid-Acting Insulin Analogs for Diabetic KetoacidosisNo difference in time to resolution of ketoacidosis ; hypoglycemic episodes; or mortalityBenefits in NNTNo one was helped with intravenous regular insulin infusion when compared to subcutaneous rapid-acting insulin analogs in regards to time to resolution of ketoacidosis, number of hypoglycemic episodes, or mortalityHarms in NNTNo one was harmed (no adverse events other than hypoglycemia reported)View As: NNT %SourceAndrade-Castellanos CA, Colunga-Lozano LE
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                            2020International Society for Pediatric and Adolescent Diabetes
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                            Additional Chapter: Diabetic Ketoacidosis in the time of COVID-19: Role of Subcutaneous insulin 'LDEHWLF.HWRDFLGRVLVLQWKHWLPHRI&29,'5ROHRI6XEFXWDQHRXVLQVXOLQ/HHQD3UL\DPEDGD-RVHSK,:ROIVGRUI6WXDUW%ULQN0DULD)ULWVFK(WKHO&RGQHU.LP&'RQDJKXH0DULD(&UDLJ'LYLVLRQRI3HGLDWULF(QGRFULQRORJ\5DLQERZ&KLOGUHQ¶V+RVSLWDO+\GHUDEDG,QGLD'LYLVLRQRI
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                            2024EvidenceUpdates
                            Trends in Incidence of Hospitalization for Hypoglycemia and Diabetic Ketoacidosis in Individuals With Type 1 or Type 2 Diabetes With and Without Severe Mental Illness in Denmark From 1996 to 2020: A Nationwide Study To examine trends in incidence of acute diabetes complications in individuals with type 1 or type 2 diabetes with and without severe mental illness (SMI) in Denmark by age and calendar year. We conducted a cohort study using nationwide registers from 1996 to 2020 to identify individuals with diabetes, ascertain SMI status (namely, schizophrenia, bipolar disorder, or major depression) and identify the outcomes: hospitalization for hypoglycemia and diabetic ketoacidosis (DKA). We used Poisson regression to estimate incidence rates (IRs) and incidence rate ratios (IRRs
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                            2024EvidenceUpdates
                            Patients with type 1 diabetes are at elevated risk of developing new hypertension, chronic kidney disease and diabetic ketoacidosis after COVID-19: Up to 40 months' follow-up The aim was to investigate whether COVID-19 increases new incidence of hypertension (HTN), chronic kidney disease (CKD) and diabetic ketoacidosis (DKA) in patients with type 1 diabetes (T1D) up to 40 months post-infection
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                            2024PLoS ONE
                            Understanding the factors influencing nurses in managing patients with diabetic ketoacidosis in the emergency departments of referral hospitals in Dar es Salaam, Tanzania: A descriptive qualitative study. The quality of nursing management of diabetic ketoacidosis (DKA) in emergency departments may be associated with either increased or decreased length of hospital stay. Despite that patient
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                            Serum Phosphorus and Hypophosphatemia During Therapy of Diabetic Ketoacidosis in Children: Single-Center, Retrospective Cohort 2016-2022. To assess factors associated with serum phosphorus (P) and hypophosphatemia in children with type 1 diabetes mellitus (T1DM) treated for diabetic ketoacidosis (DKA). Retrospective cohort. Community-based PICU in a university-affiliated hospital. Patients 1-20
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                            Predicting and Ranking Diabetic Ketoacidosis Risk among Youth with Type 1 Diabetes with a Clinic-to-Clinic Transferrable Machine Learning Model. To use electronic health record (EHR) data to develop a scalable and transferrable model to predict 6-month risk for diabetic ketoacidosis (DKA)-related hospitalization or emergency care in youth with type 1 diabetes (T1D). To achieve a sharable
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                            2025BMC Neurology
                            Euglycemic diabetic ketoacidosis associated metabolic encephalopathy caused by dapagliflozin: a rare case report. Sodium-glucose cotransporter-2(SGLT-2) inhibitors are a newer class of antidiabetic drugs with the increased risk of euglycemic diabetic ketoacidosis(EuDKA). Encephalopathy is a rare but life-threatening event of EuDKA. Due to paradoxically normal or slightly elevated serum glucose