"Long-term effects of cannabis"

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                            1
                            2020Journal of Affective Disorders
                            Short and Long-Term Effects of Cannabis on Symptoms of Post-Traumatic Stress Disorder. Many individuals use cannabis to manage symptoms of post-traumatic stress disorder (PTSD), and evidence indicates that the endocannabinoid system represents a viable target for treating these symptoms. Data from 404 medical cannabis users who self-identified as having PTSD were obtained from Strainprint®
                            2
                            2014Neuropsychopharmacology
                            Long-Term Effects of Cannabis on Brain Structure. The dose-dependent toxicity of the main psychoactive component of cannabis in brain regions rich in cannabinoid CB1 receptors is well known in animal studies. However, research in humans does not show common findings across studies regarding the brain regions that are affected after long-term exposure to cannabis. In the present study, we
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                            3
                            2024Cannabis Evidence
                            clinical trials supporting cannabis to treat PTSD. Some patients with PTSD may report experiencing short-term symptom relief when using cannabis, but PTSD symptom reduction did not differ between Veterans randomized to cannabis versus placebo in the only extant RCT. The long-term effects of cannabis use in Veterans with PTSD remain unclear. Some Veterans may experience worsening PTSD symptoms
                            4
                            2024Cannabis Evidence
                            neuropsychological decline from childhood to midlife. Proc Natl Acad Sci USA. 2012;109:E2657–64. doi: 10.1073/pnas.1206820109 14. Crean RD, Crane NA, Mason, BJ. An evidence based review of acute and long-term effects of cannabis use on executive cognitive functions. J Addict Med. 2011;5(1):1-8. doi:10.1097/ADM.0b013e31820c23fa. 15. Kroon E, Kuhns, L, Cousijn J. The short-term and long-term effects of cannabis
                            6
                            2023Canadian Centre on Substance Abuse
                            reason for use. As the legal cannabis market evolves, these trends may also evolve, and this research should be ongoing to better understand the long-term effects of cannabis legalization. Other areas worth exploring are the impact of legalization on alcohol-related outcomes (such as hospitalizations), including among specific subgroups, and the impact of proximity to cannabis stores and alcohol stores -term effects of cannabis legalization. Studies referenced in this section (see the Appendix for more details on each): • Barr, A., & Panenka, W. Understanding the relationship between recreational cannabis use and mental health in a marginalized population. • Costello, J., & MacKillop, J. Changes in substance use and mental health in two hospital-based addiction treatment programs over the course
                            7
                            2022American Heart Association
                            Trip Score
                            NarrativeNarrative based
                            EvidenceEvidence based
                            ?
                            cannabis was similar to that in the placebo group (18.21 cm versus 18.26 cm).33 These observations illustrate the differential short-term effect of THC and CBD on cognition. Evidence also suggests that the short-term effects of cannabinoids are transient and can be influenced by the development of tolerance and the use of other drugs.The long-term effect of cannabis on cognition, however, is less well
                            9
                            Case Report: Catastrophic Effects of Using Cannabis Via Bucket Bong in Top End Northern Territory of Australia. The prevalence of cannabis usage is increasing worldwide, including among both Indigenous and non-Indigenous Australians. The long-term effects of cannabis use on the lungs are well-known. However, the acute adverse effects on the lungs are sparsely reported. There are different ways
                            11
                            2020Psychological Medicine
                            capturing within-person changes suggest that cannabis use is linked with greater severity of trauma-related intrusion symptoms over time. A strong person-level directional association between PTSD and CUD was evident. Findings have significant clinical implications for the long-term effects of cannabis use among individuals with PTSD.
                            12
                            2020Pain Medicine
                            Clinical Profiles of Concurrent Cannabis Use in Chronic Pain: A CHOIR Study. Despite evidence of the analgesic benefits of cannabis, there remains a relative scarcity of research on the short- and long-term effects of cannabis use in individuals with chronic pain. The current study is a secondary analysis of clinical data from the Collaborative Health Outcomes Information Registry (CHOIR). Data
                            13
                            of addiction proposed by Koob and Volkow. The model proposes that repeated substance abuse drives neurobiological changes in the brain that can be separated into three distinct stages, each of which perpetuates the cycle of addiction. Here we review previous research on the acute and long-term effects of cannabis use on the brain and behavior, and find that the three-stage framework of addiction applies
                            14
                            2024PROSPERO
                            the prevalence of marijuana use among individuals with and without NSSI at a single point in time.Other Study Designs:Longitudinal cohort studies assessing the long-term effects of marijuana use on NSSI outcomes.Exclusion Criteria:Non-peer-reviewed literature, such as conference abstracts, editorials, letters, or opinion pieces.Animal studies or laboratory-based studies that do not involve human
                            15
                            The effects of marijuana exposure on expiratory airflow. A study of adults who participated in the U.S. National Health and Nutrition Examination Study. Given the inconclusive science on the long-term effects of marijuana exposure on lung function, the increasing tetrahydrocannabinol composition of marijuana over time, and the increasing legal accessibility of the substance, continued
                            16
                            2023PROSPERO
                            of cannabis research: Is there evidence of lasting neurocognitive effects?. PROSPERO 2023 CRD42023466560 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023466560Review questionWhat are the long-term effects of cannabis on neurocognitive function after prolonged (>25 days) of abstinence?SearchesPsycINFO, PsycArticles, PubMedReferences of selected studies and prior meta
                            17
                            2022Clinical Trials
                            on the cardiovascular system in humans. The investigators have data from cell culture and small animal studies that cannabis is toxic to the cardiovascular system. Recently legalized in Canada, the long-term effects of cannabis use on the cardiovascular system may not be apparent for several decades. The purpose of this study is to test the effect of cannabis use on the vascular system. Using a non-invasive test
                            18
                            2021Clinical Trials
                            in modulating the gut microbiome and immune system, which have been found to be disrupted by alcohol. However, it is also possible that cannabinoids, specifically delta-9-Tetrahydrocannabinol (THC), may confer harms in heavy drinkers by enhancing the intoxicating effects of alcohol. The current study will be the first to explore the acute and long-term effects of cannabis on alcohol use and neurobehavioral
                            19
                            2012The Scientific World Journal
                            Assessing Topographical Orientation Skills in Cannabis Users The long-term effects of cannabis on human cognition are still unclear, but, considering that cannabis is a widely used substance and, overall, its potential use in therapeutic interventions, it is important to evaluate them. We hypothesize that the discrepancies among studies could be attributed to the specific cognitive function
                            20
                            2006Journal of Affective Disorders
                            (OR = 0.35, 95% CI: 0.03, 3.49). As 3 years is a relative short period of follow-up, long-term effects of cannabis use on mania outcomes could not be detected. The results suggest that cannabis use may affect population expression of manic symptoms (and subsequent risk to develop bipolar disorder [Regeer, E.J., Krabbendam, L., R, DE Graaf, Ten Have, M., Nolen, W.A., Van Os, J., 2006. A prospective study