Lupusvulgaris: a narrative review. Lupusvulgaris (LV) is a type of paucibacillary cutaneous tuberculosis that can occur due to inoculation, lymphatic, or hematogenous route. It occurs in a previously sensitized individual with high immunity to tuberculosis. LV can have different morphology of presentation, which can lead to difficulty in diagnosis. The Tuberculin test is strongly positive , tuberculin test, dermoscopy, molecular test, and culture would help diagnose LV. This review discusses the introduction, pathogenesis, clinical features, differential diagnosis, investigations, complications, and treatment of lupusvulgaris in detail. This review can help the dermatologist understand the condition better with appropriate diagnosis and therapy.
A case of giant lupusvulgaris. Lupusvulgaris, the commonest form of tuberculosis of the skin, presents with a plaque that enlarges slowly with advancing edges while showing atrophy at other areas. It may be acquired by the blood stream, via lymph, by contiguous spread or from external inoculation. We describe a case of lupusvulgaris with a large erythematous-scaly plaque of 44 × 26 cm over the back and a similar 7 × 5 cm plaque over the right thigh. The plaque over the back was gradually progressive for the previous ten years and showed scarring and atrophy at places. Histopathology of the area showed caseating granulomas with Langhans giant cells, epitheloid cells and lymphocytes. A diagnosis of lupusvulgaris was made. This case is being presented owing to the large size of the lesion.
A Slowly Growing Orange Patch on the Cheek: Diagnosis of LupusVulgaris 20 Years After Onset of First Skin Changes Tuberculosis is a worldwide occurring disease that affects approximately 20-40% of the world's population and in particular in developing countries. However, in times of migration, industrialised countries are again being more and more affected. Cutaneous tuberculosis is rare and lupusvulgaris represents its most common form. Preferentially, young adults in developing or low-income countries are affected from cutaneous tuberculosis, which usually occurs in previously sensitized persons with a high degree of tuberculin sensitivity and a good immunoresponse. In Europe, more elderly people are involved. We present a case of lupusvulgaris that was diagnosed with a delay of about
Lupusvulgaris leading to perforation of nasal septum in a child Lupusvulgaris (LV) is a common form of cutaneous tuberculosis in India, mostly involving the lower half of the body. Facial involvement is uncommon. Untreated disease may lead to significant morbidity due to atrophic scarring, mutilation, and deformity. We report a case of multi-focal LV in a 10-year-old boy affecting the nose
Bindi Tuberculosis – LupusVulgaris Associated with Bindi Use: A Case Report Cutaneous lesions are relatively uncommon manifestations of tuberculosis (TB). A 40-year-old female presented with skin lesion over the forehead since two months. She used to apply bindi over the same area since past 25 years. Based on skin biopsy and other ancillary investigations, she was diagnosed as a case of lupusvulgaris and initiated on anti TB medications following which, the lesion regressed. Thus, we herein report the first case of cutaneous tuberculosis (lupusvulgaris) associated with long term use of bindi.
Spina ventosa with lupusvulgaris and lymphadenopathy: Multifocal tuberculosis Tuberculous dactylitis is a rare yet well-recognized disease of small bones of the hands and feet. It occurs in young children below five years of age. Tubercular dactylitis with lupusvulgaris and lymphadenopathy was suspected clinically and radiologically in an 8-year-old girl who had multiple soft tissue swelling
ulcerated nodules on his left upper extremity. He had a past medical history of bacille Calmette-Guerin vaccine induced lupusvulgaris. Skin biopsy of the nodules showed granulomas and neutrophil-dominated purulent inflammation. Ziehl-Neelsen staining was negative, and the cultures were positive for M. tuberculosis. Furthermore, the M. tuberculosis complex was identified using metagenomic next-generation
of CTB was confirmed on histopathology/cytology and response to standard antitubercular treatment (ATT). All details were recorded on a predesigned proforma. Of 1458 eligible patients, 803 were children. The mean disease duration was 15.3 months. Lupusvulgaris (40.4%) was the most common clinical variant, followed by scrofuloderma (32.7%) and lichen scrofulosorum (15.2%). Other variants included
as a separate entity. The true turning point in the history of lupus occurred at the beginning of the 19th century, when the distinction between lupusvulgaris and cutaneous lupus in its modern sense emerged slowly. Major subsequent contributions from Kaposi, Sequiera and Balean, and Osler enabled the recognition of the systemic nature of the disease, with its modern history being marked by the recognition
chronic ulcers, around chronic sinuses (eg, osteomyelitis), lupusvulgaris (chronic form of cutaneous tuberculosis).Genetic conditions - eg, xeroderma pigmentosum and albinism.Pre-malignant conditions - eg, Bowen's disease, areas of skin showing actinic damage. Multiple actinic keratoses are associated with an estimated 10% lifetime risk of skin cancer. Keratoacanthomas may rarely progress
* * Rheumatoid arthritis * * Dermatomyositis * * Lupusvulgaris * * Carcinoma of the breast post mastectomy * * Concomitant urinary tract infection * * Prolonged therapy with systemic corticosteroids Other rare associations that have been reported include papillary urothelial carcinoma [11] and abdominal malakoplakia following blunt trauma to the abdomen. [12