"Mebhydrolin"

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                            1
                            2023PROSPERO
                            ; “astemizole“, “clemastine”, “cyproheptadine”, “desloratadine”, “hydroxyzine”, “loratadine”, “mebhydrolin”, “pimethixene”, “promethazine”, “terfenadine”, antipsychotics; “aripiprazole”, “chlorpromazine”, “chlorprothixene”, “fluphenazine”, “flupenthixol”, “penfluridol”, “perphenazine”, “pimozide”, “promazine”, “sertindole”, “thioridazin”, “trifluoperazine”, “triflupromazine”, calcium channel blockers
                            2
                            , azithromycin, tetracycline, minocycline, vitamin E, ciclosporin, colchicine, mizoribine, mebhydrolin, infliximab and adalimumab with mycophenolate mofetil have all been reported.
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                            3
                            Three explorative studies on the efficacy of the antihistamine mebhydroline (Omeril). The efficacy of a multiple oral dose treatment with mebhydroline (Omeril coated tablets, 100 mg t.i.d.) was examined in 3 studies which were performed in a randomized, double-blind and placebo-controlled 2-way cross-over design. A second target was to investigate the suitability of different pharmacodynamic rhinitis/atopy. The mebhydroline treatment's superiority over placebo was shown statistically at the 95% confidence level for the symptoms itchy nose in study A and for nasal congestion in study B. In study C, allergen-induced weals (planimetric measurement) and itching (visual analog scale) were significantly changed by mebhydroline. A qualitative evaluation revealed a reaction intensity that differed
                            4
                            of mebhydrolin. No effect on breathlessness was detected. In contrast, the standard phenothiazine, chlorpromazine, caused a marked and statistically significant reduction in breathlessness without affecting ventilation and without causing detectable sedation. This unexpected finding merits further study in patients and is discussed with reference to the role of chlorpromazine as a constituent of Brompton's
                            10
                            2003Trip
                            Which antihistamines are safe in the first trimester of pregnancy? We contacted the National Teratology unit for their data concerning this question. Drugs during pregnancy & lactation gives the following recommendation: "First generation H1-blockers like chlorpheniramine, dexachlopheniramine, mebhydroline, clemastine and dimetidine, can be used during pregnancy for the treatment