Effect of paracetamol, mephenoxalone and their combination on pain following bone surgery. Sixty patients suffering moderate postoperative pain after bone surgery were divided randomly into 3 treatment groups on the day following operation. Under double blind conditions they received either 400 mg mephenoxalone, a weak sedative, or 900 mg paracetamol, or the same doses of these drugs simultaneously, three times daily for three days. Pain scores determined by a surgeon 1, 2, 3, and 6 hours after administration of the first dose of the drug indicated that paracetamol and paracetamol + mephenoxalone had similar analgesic effects and were more effective than mephenoxalone alone. However, during repeated administration over 3 days, the mean effect of the drug combination was slightly better
quality of life improved over the course of the study in both the [guaifenesin] and placebo groups, this improvement was not accompanied by changes in sputum properties".[26]See also[edit] * Guaiacol * Guaifenesin/phenylephrine * Methocarbamol * Mephenoxalone * Oxomemazine/guaifenesin * Plastic bronchitisReferences[edit] 1. ^ "Guaifenesin Definition & Meaning". Merriam-Webster. 2. ^ Aluri JB