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Metabolicsyndrome Skip to main contentSkip to searchAbout usHelpSubscribeAccess through your institutionLog inBMJ Best PracticeSearchSearchSelect languageMetabolic syndrome MENULog in or subscribe to access all of BMJ Best PracticeLast reviewed:7 May 2023Last updated:01 Jun 2023SummaryMetabolic syndrome is a cluster of common abnormalities, including insulin resistance, impaired glucose , although there are ethnic variations in the incidence of comorbidities associated with metabolicsyndrome defined by the same criteria.The precise pathogenetic mechanisms unifying all of its components are as yet unknown, although insulin resistance certainly plays a key role.Obesity, an atherogenic diet, and physical inactivity are the strongest risk factors for the development of metabolic
METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE - ASSESSMENT OF PATIENTS WITH OBESITY AND METABOLICSYNDROME - GUIDELINE FROM THE BRAZILIAN SOCIETY OF BARIATRIC AND METABOLIC SURGERY Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease in the world and was recently renamed to emphasize its metabolic component. This article seeks
Primary care: COVID-19 and metabolicsyndrome: could diet be the key? COVID-19 and metabolicsyndrome: could diet be the key? ======================================================= * Maryanne Demasi * diabetes mellitus * endocrinology * nutritional sciences * policy In the current COVID-19 pandemic, governments mandate social distancing and good hand hygiene, but little attention is paid who have fallen seriously ill with COVID-19 were overweight or obese and 99% of deaths in Italy have been in patients with pre-existing conditions, such as hypertension, diabetes and heart disease.3 These conditions, collectively known as metabolicsyndrome, are linked to impaired immune function,4 and more severe [symptoms](https://jamanetwork.com/journals/jama/fullarticle/2765184?guestAccessKey
Neck circumference cutoff point as a predictor of metabolicsyndrome in Brazilian rural workers. Neck circumference (NC) is a predictive measure for the diagnosis of MetabolicSyndrome (MS). The aim of the present study was to establish cutoff points for NC as a predictor of the presence of MS in Brazilian rural workers, based on the MS components according to the IDF and NCEP-ATP III criteria
Physical activity and metabolicsyndrome in primary care patients in Spain. To determine the relationship between self-reported physical activity and the components of premorbid metabolicsyndrome in patients treated in primary care according to sex. Cross-sectional descriptive study conducted on a sample of 2,359 patients without cardiovascular disease or diabetes, included in the cohort high). The analyses were performed stratifying by sex. A total of 854 men and 1,505 women with no identified diseases were included. Women were more sedentary than men (p<0.004; OR = 1,35; IC95% = 1,10-1,65) and presented lower values in all the components of the metabolicsyndrome, except for HDL-cholesterol, which was higher (p<0.001). The adjusted ANOVA model shows that diastolic blood pressure
Accuracy of the Modified Finnish Diabetes Risk Score (Modified FINDRISC) for detecting metabolicsyndrome: Findings from the Indonesian national health survey. This study evaluated the diagnostic accuracy of the Modified Finnish Diabetes Risk Score (Modified FINDRISC) for detecting individuals with metabolicsyndrome in Indonesia. A dataset from the 2018 Indonesian National Basic Health Survey was analysed, and cases of metabolicsyndrome were identified in accordance with both National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III) and International Diabetes Federation (IDF) guidelines. Diagnostic accuracy of the Modified FINDRISC tool was evaluated using the Area Under the Receiver Operating Characteristic (AUC) curve, while optimal cut-off scores were determined
Associations between religiosity/spirituality with insulin resistance and metabolicsyndrome in the Midlife in the United States (MIDUS) study. Religiosity and spirituality (R/S) are central aspects to the lives of many people worldwide. Previous research suggests a potentially beneficial relationship between R/S, mostly understood as religious service attendance, and mortality. Though important , this research often fails to account for the complex and multidimensional nature of R/S. Also lacking is an adequate understanding of the physiological mechanisms that may link R/S with mortality and other health outcomes. Insulin resistance and metabolicsyndrome, subclinical physiological processes that are influenced by the types of lifestyle factors and psychological factors that R/S addresses, serve
Associations between spice or pepper (Capsicum annuum) consumption and diabetes or metabolicsyndrome incidence. Spice and pepper are recognized as sources of antioxidants and anti-inflammatory compounds. This study investigated the association between spice or pepper intake and metabolicsyndrome (MetS), related risk factors, or type 2 diabetes (T2D) incidences. The qualified Tehran Lipid and Glucose Study (TLGS) participants were included. In all examinations, dietary, anthropometrical, and biochemical variables were measured. Multivariable Cox proportional hazards regression models were exploited to determine the relationship between spice or pepper consumption and the hazard ratios for Type 2 Diabetes (T2D), MetabolicSyndrome (MetS), or its components. The analysis was performed on 5340
Application of attenuated total reflection-Fourier transform infrared spectroscopy in semi-quantification of blood lipids and characterization of the metabolicsyndrome. Dyslipidemia, a hallmark of metabolicsyndrome (MetS), contributes to atherosclerotic and cardiometabolic disorders. Due to days-long analysis, current clinical procedures for cardiotoxic blood lipid monitoring are unmet
The efficacy of Lacticaseibacillus paracasei MSMC39-1 and Bifidobacterium animalis TA-1 probiotics in modulating gut microbiota and reducing the risk of the characteristics of metabolicsyndrome: A randomized, double-blinded, placebo-controlled study. Modern treatment, a healthy diet, and physical activity routines lower the risk factors for metabolicsyndrome; however, this condition is associated with all-cause and cardiovascular mortality worldwide. This investigation involved a randomized controlled trial, double-blind, parallel study. Fifty-eight participants with risk factors of metabolicsyndrome according to the inclusion criteria were randomized into two groups and given probiotics (Lacticaseibacillus paracasei MSMC39-1 and Bifidobacterium animalis TA-1) (n = 31) or a placebo (n
Health Effects of Electrolyzed Hydrogen Water for the MetabolicSyndrome and Pre-MetabolicSyndrome: A 3-Month Randomized Controlled Trial and Subsequent Analyses. We studied the effect of three months' use of electrolyzed hydrogen water (EHW, Electrolyzed Hydrogen Water conditioner produced by Nihon Trim Co., Ltd.) on metabolic and pre-metabolicsyndrome groups. This research was carried out jointly by Susaki City; Nihon Trim Co., Ltd.; and Kochi University as part of a local revitalization project with health as a keyword. A randomized, placebo-controlled, double-blind, parallel-group trial was conducted to evaluate the clinical impact of EHW on participants who suffered from metabolicsyndrome or pre-metabolicsyndrome. EHW was produced via electrolysis using a commercially available
Estimating the impact of metabolicsyndrome on low back pain and the joint effects of metabolicsyndrome and depressive symptoms on low back pain: insights from the China Health and Retirement Longitudinal Study. Although metabolicsyndrome (MetS) and depressive symptoms (DS) are predictors of low back pain (LBP), their combined effects and relative contributions to LBP have not been well
The effect of a new developed synbiotic yogurt consumption on metabolicsyndrome components in adults with metabolicsyndrome: a randomized controlled clinical trial. Studies have proposed that probiotic intake may ameliorate some of the clinical components of metabolicsyndrome (MetS). This study aimed to determine the effects of a new developed synbiotic yogurt containing Lactobacillus
Aminotransferases as causal factors for metabolicsyndrome: A bidirectional Mendelian randomization study. Circulating aminotransferases (ALT and AST) have been used as biomarkers for liver injury. The causal relationships between aminotransferases and metabolicsyndrome remain ambiguous. We conducted bidirectional and multivariable Mendelian randomization (MR) analyses between aminotransferases and traits related to metabolicsyndrome using genetic variants obtained from genome-wide association studies (GWASs). MR-PRESSO tests were adopted to remove outliers and eliminate pleiotropy. MR steiger tests were conducted to ensure the correct direction of the causal effects. Both aminotransferases were risk factors for essential hypertension. ALT is a risk factor for type 2 diabetes. The bidirectional
Association between dental scaling and metabolicsyndrome and lifestyle. Periodontal disease is a risk factor for diabetes and metabolicsyndrome, and non-surgical periodontal treatment has been shown to help maintain stable blood sugar in diabetic patients. Determining the level of preventive scaling in patients with metabolicsyndrome will help manage the disease. The purpose of this study was to investigate the extent to which people with metabolicsyndrome or bad lifestyle performed scaling and the association between preventive scaling and metabolicsyndrome or lifestyle in a large population. This study was conducted on adults aged 20 years or older from January 2014 to December 2017 in the National Health Insurance System (NHIS) database. Among 558,067 people who underwent health checkups
Nutrition and Health in Arab Adolescents (NaHAR): Study protocol for the determination of ethnic-specific body fat and anthropometric cut-offs to identify metabolicsyndrome. The prevalence of adolescent obesity in the Middle-East is considered among the highest in the world. Obesity in adolescents is associated with several cardiometabolic abnormalities, the constellation of which is referred to as the metabolicsyndrome (MetS). This multi-country cross-sectional study aims to determine the optimal cut-off values for body fat (BF); body mass index (BMI) z-score; waist circumference (WC) percentile, and mid-upper arm circumference (MUAC) for the prediction of MetS among adolescents from Kingdom of Saudi-Arabia (KSA), Kuwait, Jordan, Lebanon and Syria. A secondary objective is to examine the validity
Effects of niacin and omega-3 fatty acids on HDL-apolipoprotein A-I exchange in subjects with metabolicsyndrome. HDL-apolipoprotein A-I exchange (HAE) measures a functional property associated with HDL's ability to mediate reverse cholesterol transport. HAE has been used to examine HDL function in case-control studies but not in studies of therapeutics that alter HDL particle composition . This study investigates whether niacin and omega-3 fatty acids induce measurable changes in HAE using a cohort of fifty-six subjects with metabolicsyndrome (MetS) who were previously recruited to a double-blind trial where they were randomized to 16 weeks of treatment with dual placebo, extended-release niacin (ERN, 2g/day), prescription omega-3 ethyl esters (P-OM3, 4g/day), or the combination. HAE
Association between human papillomaviruses, metabolicsyndrome, and all-cause death; analysis of the U.S. NHANES 2003-2004 to 2015-2016. Human papillomavirus (HPV) is the most common sexually transmitted infection, attributed to 4.5% of all cancers worldwide. Co-infection with the metabolicsyndrome (MetS), a common cluster of cardiometabolic risk factors, has been shown to increase
A cohort study of the effects of social support on cerebral cardiovascular disease in subjects with metabolicsyndrome. Previous studies have extensively examined the relationship between social support and various health outcomes. However, little is known about the distinct longitudinal associations between perceived social support and the development of cardiovascular events in patients with metabolicsyndrome. In this cohort study, we investigated whether the levels of perceived social support in patients with metabolicsyndrome were associated with an increased risk of cerebrovascular and cardiovascular events. The level of social support was assessed using the Medical Outcomes Study-Social Support Survey (MOS-SSS) in 2,721 individuals living in Wonju and Pyeongchang, South Korea
The impact of metabolicsyndrome severity on racial and ethnic disparities in Metabolic Dysfunction-Associated Steatotic Liver Disease. Previous studies have examined the effects of metabolicsyndrome (MetS) rather than its severity on race and ethnic disparities in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). We used the MetS severity score, a validated sex-race-ethnicity