"Mixed affective state"

Efficacy of Acute Pharmacologic Interventions in Mixed Affective State: A Network Meta-Analysis and Ranking PROSPEROInternational prospective register of systematic reviews Print | PDFEfficacy of Acute Pharmacologic Interventions in Mixed Affective State: A Network Meta-Analysis and RankingBenjamin Trnka, Deepti Anbarasan, Justin Morales, Diego RenteriaTo enable PROSPERO to focus on COVID-19 , Justin Morales, Diego Renteria. Efficacy of Acute Pharmacologic Interventions in Mixed Affective State: A Network Meta-Analysis and Ranking. PROSPERO 2023 CRD42023455054 Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023455054Review questionWhat is the comparative effectiveness of pharmacologic interventions for the acute treatment of manic and depressive symptoms

in pregnancy. Follow the MHRA safety advice on the use of valproate. [2014, amended 2023] 1.5.13 If the clinical presentation is of a mixed affective state, characterised by both manic and depressive symptoms, follow recommendations 1.5.1 to 1.5.12 for the treatment of mania, and monitor closely for the emergence of depression. [2014] 1.5.14 Do not offer lamotrigine to treat mania. [2014] For a short

any exposure in pregnancy. See the MHRA safety advice on valproate use by women and girls. [amended 2020] [amended 2020] 1.5.9 If the clinical presentation is of a mixed affective state, characterised by both manic and depressive symptoms, follow recommendations 1.5.1 to 1.5.8 for the treatment of mania, and monitor closely for the emergence of depression. 1.5.10 Do not offer lamotrigine to treat

-8.24.Lee A, Woo J, Ito S. Frequency of infant adverse events that are associated with citalopram use during breast-feeding. Am J Obstet Gynecol 2004;190:218-21. [PubMed]25.Ritz S. Quetiapine monotherapy in post-partum onset bipolar disorder with a mixed affective state. Eur Neuropsychopharmacol 2005;15 (Suppl 3):S407. doi:10.1016/S0924-977X(05)80825-9 [CrossRef]26.Hale TW, Kendall-Tackett K, Cong Z

depression during breast-feeding. Int J Neuropsychopharmacol 2004;7 (Suppl 2):S245. P01.431. doi:10.1017/S146114570400454710.1017/S1461145704004547 [CrossRef] [CrossRef]18.Ritz S. Quetiapine monotherapy in post-partum onset bipolar disorder with a mixed affective state. Eur Neuropsychopharmacol 2005;15 (Suppl 3):S407. doi:10.1016/S0924-977X(05)80825-9 [CrossRef]19.Gentile S. Quetiapine-fluvoxamine

) (Viguera et al., 2007b).Immediately after childbirth the risk of postpartum psychosis (including mania, mixed affective states and psychotic depres-sion) and episodes of bipolar disorder increases in women with bipolar disorder, but there is some debate as to what extent. A recent meta-analysis of studies reporting on postpartum recur-rences found that the rates varied

is limited, mixed affective states were not assessed, and analyses were cross-sectional. Patients have an increased risk of suicidal ideation when PTSD is comorbid with BD.

sleep hygiene measures (eg, bedtime routines, avoiding caffeine, reduced activity before sleep)[18].Low-dose amitriptyline or chlorpromazine can be given if the problem is serious and chronic and does not respond to sleep hygiene measures.Electroconvulsive therapyThis may be considered for pregnant women who have:Severe depression.Severe mixed affective states or mania in the context of bipolar

. This may include gradual withdrawal of medication, instituting psychological therapy and/or switching to a drug with fewer adverse effects.Electroconvulsive therapy (ECT)Electroconvulsive therapy (ECT) should be considered for pregnant women with severe depression, severe mixed affective states or mania, or catatonia, whose physical health or that of the fetus is at serious risk.ReferralUrgently refer

. Postpartum psychosis is largely affective in nature, although several studies comment on atypical features in the presentation such as mixed affective state, confusion and disturbed behaviour.50 It typically presents in the early postnatal period, usually within the first month. There is a close link with bipolar affective disorder; the risk of developing postpartum psychosis being

Mixed States in Bipolar Disorder: Etiology, Pathogenesis and Treatment Many bipolar disorder patients exhibit mixed affective states, which portend a generally more severe illness course and treatment resistance. In the previous renditions of Diagnostic and Statistical Manual mixed states were narrowly defined in the context of bipolar I disorder, but with the advent of DSM-5 the term "mixed

admission, referral to continuation ECT treatment, number of readmissions, and time until next readmission. Conclusions. Our results support the effectiveness of ECT in patients experiencing a mixed affective state.

Effect of cariprazine across the symptoms of mania in bipolar I disorder: Analyses of pooled data from phase II/III trials. Bipolar I disorder is a chronic disorder characterized by episodic recurrences of mania, depression, and mixed affective states interspersed with periods of full or partial remission; subsyndromal residual symptoms between episodes are common and disabling. Cariprazine

to be greatest in the years soon after diagnosis in younger patients. In some study populations deaths from suicide in BD made up one quarter of all suicide deaths.Individual factors such as male gender, active psychiatric symptoms (especially co-existing anxiety disorder, dysphoria or a mixed affective state), previous history of suicide attempts, recent admission or discharge from a psychiatric hospital

disorder. Mixed episodes are common in fathers at postpartum, posing a higher suicide risk than depressive and manic/hypomanic episodes. Therefore, in order to reduce the suicide risk, clinicians should address and treat adequately mixed affective states in this specific population.