Diabetic NeuropathicArthropathy of the Knee: Two Case Reports and a Review of the Literature Diabetic neuroarthropathy of the knee or Charcot knee (CK) is a lesser-known complication of diabetes mellitus, with a limited number of case reports and small case series published in the literature. The majority of these reports describe the complexities and challenges that arise in these patients
Outcome after protected full weightbearing treatment in an orthopedic device in diabetic neuropathicarthropathy (Charcot arthropathy): a comparison of unilaterally and bilaterally affected patients. Charcot neuropathicarthropathy (CN) is a chronic, progressive, destructive, non-infectious process that most frequently affects the bone architecture of the foot in patients with sensory neuropathy
Charcot NeuropathicArthropathy of the Foot: A Literature Review and Single-Center Experience Charcot neuropathic osteoarthropathy of the foot is a relatively common complication of diabetic neuropathy. Incorrect diagnosis and improper treatment often result in the extremity having to be amputated. This paper summarises the current view on the etiology, diagnostics, and treatment of diabetic
Unilateral neuropathicarthropathy of the shoulder secondary to syringomyelia: Diagnostic challenges Neuropathicarthropathy of the shoulder is a rare disorder characterized by joint degeneration, and is associated with loss of sensory innervation. Syringomyelia is a disease in which fluid-containing cavities (syrinxes) form within the spinal cord. Here, we report a case of neuropathicarthropathy of the shoulder secondary to syringomyelia in a 40-year-old woman. X-rays of the left shoulder revealed damage to bone and joint architecture. Blood tests indicated vitamin D deficiency and secondary hyperparathyroidism. Magnetic resonance imaging of the cervical spine showed a large syrinx from the second cervical spine to the second dorsal spine. Although neuropathicarthropathy is uncommon
Who was first to diagnose and report neuropathicarthropathy of the foot and ankle: Jean-Martin Charcot or Herbert William Page? In November 1883, Jean-Martin Charcot and Charles Féré reported on bone and joint disease of the foot in cases of tabes dorsalis, and referred to the condition as 'pied tabétique'--a disabling neuropathic osteoarthropathy that we usually now refer to as the Charcot foot
for aseptic loosening, osteomyelitis, or periprosthetic fractures. Unfortunately, the specificity of bone scans is low, and new bone formation can also be seen in normal or abnormal postoperative bony remodeling and neuropathicarthropathy in addition to acute fractures, periprosthetic infection, or aseptic prosthetic loosening. Typical bone scans are either a single or a 3-phase study. The standard of WBC and marrow imaging is not only to differentiate neuropathicarthropathy from acute osteomyelitis but also to differentiate aseptic loosening from acute osteomyelitis. Like neuropathicarthropathy, aseptic loosening will demonstrate spatially congruent WBC and marrow activity, consistent with reactive or hematopoietically active marrow. However, in acute osteomyelitis, In-111-labeled WBCs
Bilateral total knee arthroplasty with modified primary components in the management of neuropathicarthropathy related to chronic pancreatitis: a case with 5-year follow-up Although neuropathicarthropathy of the foot and ankle joints in diabetes is well known, the involvement of the knee joint is rare. Then, the management, particularly the use of arthroplasty, is a matter of debate. We report
reconstruction is planned [11].As previously mentioned, MRI is the imaging modality of choice for investigating the possibility of OM in the feet, having both high sensitivity (77–100%) and specificity (80–100%) [77, 82,83,84]. Unsurprisingly, distribution of OM mirrors that of ulceration, which is most common at the toes, metatarsal heads, calcaneus, and malleoli. On the contrary, neuropathicarthropathy
Not Appropriate ☢☢☢ US foot Usually Not Appropriate O ACR Appropriateness Criteria® 2 Suspected Osteomyelitis of the Foot Variant 2: Soft-tissue swelling without ulcer. Suspected osteomyelitis or early neuropathicarthropathy changes of the foot in patients with diabetes mellitus. Additional imaging following radiographs. Procedure Appropriateness Category Relative Radiation Level MRI osteomyelitis of the foot in patients with diabetes mellitus with or without neuropathicarthropathy. Additional imaging following radiographs. Procedure Appropriateness Category Relative Radiation Level MRI foot without and with IV contrast Usually Appropriate O MRI foot without IV contrast Usually Appropriate O CT foot with IV contrast May Be Appropriate ☢ CT foot without IV
imaging findings help differentiate spinal neuropathicarthropathy from disk space infection? Initial experience. Radiology. 2000;214(3):693-699. 26. Chimelli L. Tumors and tumorlike lesions of the spine and spinal cord. Neuroimaging Clin N Am. 2001;11(1):viii, 79-110. 27. Paulson EK, Sheafor DH, Enterline DS, McAdams HP, Yoshizumi TT. CT fluoroscopy--guided interventional
Multi-joint Charcot arthropathy caused by cervical spondylotic myelopathy and adult degenerative scoliosis with syringomyelia: a case report. Charcot arthropathy, also known as neuropathicarthropathy, is a rare disease whose early diagnosis and treatment are very difficult. Generally, diabetes is considered the most common cause of Charcot arthropathy. Although Charcot arthropathy of other
Establishment of a Neurodegenerative Charcot Mouse Model. This study aimed to mimic the changes from Charcot neuropathicarthropathy in humans by examining the effects of exposing diet-induced obese (DIO) mice to neurotrauma through a regimented running protocol. Forty-eight male wild-type C57BL/6J mice were obtained at age 6 weeks and separated into 2 groups for diet assignment. After a 1-week that ran ( < .001 for each parameter). Changes akin to the earliest changes observed in or before joint destruction identified in diabetic Charcot neuropathicarthropathy in humans were observed. There is currently no standard of treatment for patients with Charcot neuropathicarthropathy. This study establishes a protocol for an animal model that can be used to study and compare interventions to treat
progressiva. The first approved clinical use (1977) was for treatment of Paget's disease of bone. Other approved indications are hypercalcemia of malignancy and heterotopic ossification, with a host of off-label uses (including fibrous dysplasia, periodontal disease, multiple myeloma, neuropathicarthropathy, pulmonary microlithiasis, diabetic retinopathy, bone metastases, melorheostosis, urinary stone
Clinical insights into Charcot foot. Charcot neuropathicarthropathy (CN) is a devastating condition resulting in non-reducible foot deformity that places patients with distal peripheral neuropathy at risk for the development of chronic neuropathic foot ulcers, major lower extremity amputation, and even death. The condition is often misdiagnosed early in its presentation because of a lack
2013 Aug 18.Trieb K; The Charcot foot: pathophysiology, diagnosis and classification. Bone Joint J. 2016 Sep98-B(9):1155-9. doi: 10.1302/0301-620X.98B9.37038.Diabetic foot problems: prevention and management; NICE Guidelines (August 2015 - last updated October 2019)Harris A, Violand M; Charcot Neuropathic Osteoarthropathy.Chan RLS, Chan CH, Chan HF, et al; The many facets of neuropathicarthropathy
arthroplasty and postsurgical infection (n = 2), 1 patient with elbow arthrodesis due to neuropathicarthropathy, and postsurgical infection after open reduction and internal fixation of olecranon fractures (n = 2). All patients had a BR muscle flap and skin grafting. Orthopedic hardware was removed in 3 cases. At the mean follow-up of 45 months (range, 26-61 months), all patients had viable and functional
Charcot arthropathy of the shoulder joint as a presenting feature of basilar impression with syringomyelia: A case report and literature review. Charcot arthropathy, also known as Neuropathicarthropathy (NA), is an unusual chronic degenerative disease. To date, there exists a paucity of research on NA caused by syringomyelia. A 52-year-old non-diabetic female presented with progressive swelling , pain and limited movement in her left shoulder joint combined with asthenia of her left upper extremity for three months. Neuropathicarthropathy of the shoulder associated with the cervicothoracic syrinx and basilar impressions was diagnosed. The treatment is directed to its potential cause to cease its progression. A posterior fossa decompression (PFD) was conducted for this patient
spinal surgery, proximal migration of the level of the sensorineural loss negatively affected the polyneuropathy and eventually resulted in Charcot knee joint in a short period of time. However, the etiology of the neuropathicarthropathy hasn't been well described yet, it is usually seen at patients with diabetes mellitus as a long-term complication with or without polyneuropathy. In addition to the spinal canal pathologies, it is reported that Charcot arthropathy can be seen even after spinal anesthesia procedures. In conclusion, spinal procedures should be applied with extra caution on the patients with polyneuropathy or any neuropathicarthropathy. It should be remembered that it is possible to encounter unexpected complications such as proximally migration of the level of sensorineural loss
The Charcot foot: pathophysiology, diagnosis and classification. Neuropathic changes in the foot are common with a prevalence of approximately 1%. The diagnosis of neuropathicarthropathy is often delayed in diabetic patients with harmful consequences including amputation. The appropriate diagnosis and treatment can avoid an extensive programme of treatment with significant morbidity