"Oropharyngeal cancer"

Oropharyngeal cancer Skip to main contentSkip to searchLog inEnglish#{autosuggest.search}#{autosuggest.search}Oropharyngeal cancer MENULog in or subscribe to access all of BMJ Best PracticeLast reviewed:6 Nov 2023Last updated:05 Dec 2023SummaryOropharyngeal carcinoma is strongly associated with tobacco and alcohol use. Human papillomavirus infection is strongly implicated in people not exposed

Oral cavity and oropharyngeal cancers – surgical treatments MenuNO BIAS. NO MISINFORMATION. NO SPIN. JUST WHAT YOU NEED!The Dental ElfHomeAboutCategoriesPodcastsSearchOral cavity and oropharyngeal cancers – surgical treatmentsNo Responses »SEP42023Posted byDerek RichardsOral cavity and oropharyngeal cancer were grouped under the term oral cancer but are now considered two distinct cancers because cancer is increasingly associated with human papillomavirus (HPV). Diagnosis of HNC is mainly at an advanced stage, with implications for treatment and prognosis. Surgery plays an important part in management of oral cavity and oropharyngeal cancer and may be combined with radiotherapy, chemotherapy, or immunotherapy/ biotherapy.The aim of this Cochrane review update was to evaluate the relative

Oral cavity and oropharyngeal cancers – surgical treatments MenuNO BIAS. NO MISINFORMATION. NO SPIN. JUST WHAT YOU NEED!The Dental ElfHomeAboutCategoriesPodcastsSearchOral cavity and oropharyngeal cancers – surgical treatmentsNo Responses »SEP42023Posted byDerek RichardsOral cavity and oropharyngeal cancer were grouped under the term oral cancer but are now considered two distinct cancers because cancer is increasingly associated with human papillomavirus (HPV). Diagnosis of HNC is mainly at an advanced stage, with implications for treatment and prognosis. Surgery plays an important part in management of oral cavity and oropharyngeal cancer and may be combined with radiotherapy, chemotherapy, or immunotherapy/ biotherapy.The aim of this Cochrane review update was to evaluate the relative

Oropharyngeal Cancer Skip to main contentAn official website of the United States governmentEspañolMenuSearchHome Cancer Types Head and Neck Cancer Health Professional Adult Treatment Oropharyngeal Cancer Treatment (Adult) (PDQ®)–Health Professional VersionPrintEmailOropharyngeal Cancer Treatment (Adult) (PDQ®)–Health Professional VersionGo to Patient VersionON THIS PAGEGeneral Information and MortalityEstimated new cases and deaths from oropharyngeal cancer (included with oral cavity cancer) in the United States in 2023:[1]New cases: 54,540.Deaths: 11,580.Oropharyngeal cancer is increasing in incidence, which is attributed to the rise in human papillomavirus (HPV)-associated oropharyngeal cancer. Men are more than twice as likely as women to have oropharyngeal cancer.[1-3]AnatomyAnatomically

Chemotherapy for oral cavity and oropharyngeal cancer Chemotherapy for oral cavity and oropharyngeal cancer - National Elf ServiceMenu * * Take your event #BeyondTheRoom * Training * #ElfHelp * Contact us * NewsSearch National Elf Service No bias. No misinformation. No spin. Just what you need! The Dental Elf * Home * About * Categories * Cost effectivenessEvaluation and impact are the main risk factors with a higher incidence in men being attributed to greater exposure to these risk factors. Squamous cell carcinoma is the most common cancer of the oral cavity accounting for about 95% of cancers with primary treatment involving surgery or radiotherapy. Oropharyngeal cancers have a different aetiology and are strongly associated with human papilloma virus (HPV) and primary treatment

Distinct immunological features of oropharyngeal cancer peritumoral tonsillar tissues from inflammatory tonsils and regional lymph nodes: A pilot study. Cancer immune responses are generated in secondary lymphoid organs, such as the lymph nodes and tonsils. In the current study, transcriptional profiles of peritumoral tonsillar tissues (PTTs) from oropharyngeal cancers (OPCs) were assessed

Can predictive factors determine the time to treatment initiation for oral and oropharyngeal cancer? A classification and regression tree analysis. This ecological study aimed to identify the factors with the greatest power to discriminate the proportion of oral and oropharyngeal cancer (OOC) records with time to treatment initiation (TTI) within 30 days of diagnosis in Brazilian municipalities

Lymph node metastasis regulation by peritumoral tonsillar tissue mitochondria-related pathway activation in oropharyngeal cancer. Immune-related gene expression profiles of peritumoral tonsillar tissues are modified by oropharyngeal cancer (OPC) nodal status. This study explored immunometabolism and immune cell count alterations in peritumoral tonsillar tissue according to OPC nodal status

The role of surgery and deescalation for HPV-related oropharyngeal cancer. Recently published and ongoing trials are helping to define the role of transoral robotic surgery for oropharyngeal cancer. Evidence to date supports the use of surgery as a valuable tool in the multidisciplinary deescalation of low-risk human papillomavirus-related oropharyngeal squamous cell carcinoma.

Tumor-intrinsic and immune-related features associated with treatment failure in human papillomavirus-related oropharyngeal cancer. Limited understanding of the biology predisposing certain human papillomavirus-related (HPV+) oropharyngeal squamous cell carcinomas (OPSCCs) to relapse impedes therapeutic personalization. We aimed to identify molecular traits that distinguish recurrence-prone

Impact of Transoral Robotic Surgery Versus Radiation on Swallowing Function in Oropharyngeal Cancer Patients: A Sub-Study From a Randomized Trial. This ORATOR sub-study evaluated swallowing physiology in patients treated with transoral robotic surgery (TORS) versus radiotherapy (RT) for early-stage oropharynx cancer. Swallowing physiology was evaluated using videofluoroscopy and outcomes were

Oropharyngeal cancer incidence and trends in Brazil. Oropharyngeal cancer (OPC) incidence is rising globally, predominantly in high-income countries due to human papillomavirus (HPV) infection. However, further data on OPC incidence in Brazil is needed. The aim of this study was to estimate the incidence, trends, and predictions of OPC in Brazilian population-based cancer registries (PBCRs

Final results from a longitudinal observation study evaluating sexual health and facial appearance and distress in human papillomavirus-associated oropharyngeal cancer survivors treated with chemoradiotherapy: Sexual health and facial appearance in HPV O This communication reports on the complete results of a prospective study evaluating sexual health and appearance-related outcomes in human papillomavirus-associated oropharyngeal cancer (HPVOPC) survivors treated with (chemo)radiotherapy ((C)RT). One hundred HPVOPC patients scheduled to receive curative-intent (C)RT were enrolled onto a longitudinal observational study between October 2020 and November 2021. Sexual health was measured using the EORTC Sexual Health Questionnaire (QLQ-SHQ22) and appearance-related issues were measured using FACE-Q

Fine needle aspiration cytology including the analysis of human papilloma virus (HPV) DNA enhances the diagnostic workup of solitary cystic neck lesions in a population with a high incidence of HPV positive oropharyngeal cancer. Distinguishing branchial cleft cysts (BrCCs) from cystic metastases of human papillomavirus (HPV) positive tonsillar or base of tongue squamous cell carcinoma and cancer

Impact of screening for HPV-positive oropharyngeal cancers: a microsimulation-based modeling study. We estimated the impact of screening on morbidity and mortality of HPV16-positive oropharyngeal cancer among US men aged 45-79 years. We developed an individual-level, state-transition natural history microsimulation model to estimate the impact of screening using oral HPV16 detection, HPV16-E6  = 54,881,311), 163,958 clinically diagnosed HPV-positive oropharyngeal cancers and 32,009 deaths would occur through age 84 in the absence of screening. Assuming very-fast progression, 4%, 20%, 31%, and 60% of these cancers would be detected by one-off, 5-yearly, 3-yearly, and annual screening. Annual screening (very-fast progression) could reduce the number of cancers diagnosed at advanced stages (AJCC 7

Imaging extranodal extension (iENE) predicts higher rates of distant recurrence for HPV-positive oropharyngeal cancer: Imaging extranodal extension in HPV+ OPC. Pathologic extranodal extension is a known predictor of poor outcomes in head and neck cancer. However, data on imaging-identified extranodal extension (iENE) in oropharyngeal cancer (OPC) outcomes is limited. This study aimed

Margin Status and Recurrence in Surgically Treated Patients With HPV+ Oropharyngeal Cancer. The optimal margins for surgically treated human papilloma virus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) remain undefined. We evaluated the impact of surgical margins on progression-free survival (PFS) in patients with HPV+ OPSCC treated with primary transoral robotic surgery (TORS

Volume Outcome Relationships of Oropharyngeal Cancer Patients Undergoing Transoral Robotic Surgery. We aim to demonstrate whether facility case volume is associated with (1) perioperative outcomes and (2) overall survival in patients with oropharyngeal cancer (OPC) undergoing transoral robotic surgery (TORS). This is a retrospective cohort analysis of adults with OPC who underwent TORS between

The influence of tobacco use, hazardous drinking, and other risk factors on HPV-associated oropharyngeal cancer risk and screening perceptions among gay and bisexual men: a cross-sectional study. Oropharyngeal cancer is the eighth most common cancer among US men and its incidence is sharply rising. Oropharyngeal cancer manifests in two major ways: the classic form is prevalent among people who use alcohol and tobacco heavily, while a growing subset of incident cases is associated with human papillomavirus-16 (HPV) and transmitted via oral sex. Gay and bisexual men appear at higher risk for each etiologic subset of oropharyngeal cancer than heterosexual men. We conducted a cross-sectional study to learn how tobacco use, hazardous drinking, and other key risk factors affect gay and bisexual

International multispecialty expert physician preoperative identification of extranodal extension in patients with oropharyngeal cancer using computed tomography: Prospective blinded human inter-observer performance evaluation. Pathologic extranodal extension (pENE) is a crucial prognostic factor in oropharyngeal cancer (OPC), but determining pENE from imaging has high inter-observer variability