Summary - Cryotherapy for the prevention of taxane-induced peripheralneuropathy Cryotherapy for the prevention of taxane-induced peripheralneuropathy English summary Une production de l’Institut national d’excellence en santé et en services sociaux (INESSS) MARCH 2023 1 SUMMARY Cryotherapy for the prevention of taxane-induced peripheralneuropathy Many solid tumours are treated with chemotherapy drugs, including those in the taxane family. These drugs can have significant adverse effects, especially symptoms of chemotherapy-induced peripheralneuropathy (CIPN). These symptoms manifest as sensory and motor disorders and as pain in the upper and lower limbs. The symptoms are associated with poorer quality of life. The incidence of peripheral
Spinal cord stimulation for adults with chronic chemotherapy-induced peripheralneuropathy AAAReports & Guidance > Spinal cord stimulationSpinal cord stimulationRegister an interest in this topicTOPIC STATUS Complete Spinal cord stimulation for adults with chronic chemotherapy-induced peripheral neuropathy.Summary Health Technology Wales researchers searched for evidence on the clinical effectiveness and cost effectiveness of on the use of spinal cord stimulation for chronic chemotherapy-induced peripheralneuropathy. HTW’s Assessment Group decided not to progress the topic further as there is existing NICE guidance covering the use of this technology for chronic pain of neuropathic origin.Topic Exploration ReportTER460 05.2023TERView PDFHealth Technology Wales PartnersAdjust contrastQuick
Neuropad for screening and detection of early signs of diabetic peripheralneuropathy Neuropad - Health Technology Wales * CymraegX Search * Home * About * Reports & Guidance * Suggest a topic * Digital Open Topic Call 2022 * Impact * News & Events * Scientific Advice Service * COVID-19 * Contact * Home * About * Reports & Guidance * Suggest a topic * Digital Open Topic Call 2022 * Impact * News & Events * Scientific Advice Service * COVID-19 * ContactReports & Guidance > NeuropadNeuropadTopic Status Complete Neuropad for screening and detection of early signs of diabetic peripheral neuropathySummaryHealth Technology Wales researchers searched for evidence on the use of Neuropad for screening and detection of early signs of diabetic peripheralneuropathy. HTW’s Assessment Group decided
Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheralneuropathy in adults NHS England » Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheralneuropathy in adults Skip to main content Cookies on the NHS England websiteWe’ve put some small files called cookies on your device to make our site work.We’d also like to use analytics cookies. These send * Commissioning * Get involvedOur advice for clinicians on the coronavirus is here.If you are a member of the public looking for information and advice about coronavirus (COVID-19), including information about the COVID-19 vaccine, go to the NHS website. You can also find guidance and support on the GOV.UK website.Rituximab for the treatment of IgM paraproteinaemic demyelinating peripheralneuropathy
Exploring the role of mitochondrial-associated and peripheralneuropathy genes in the pathogenesis of diabetic peripheralneuropathy. Diabetic peripheralneuropathy (DPN) is a prevalent and serious complication of diabetes mellitus, impacting the nerves in the limbs and leading to symptoms like pain, numbness, and diminished function. While the exact molecular and immune mechanisms underlying DPN remain incompletely understood, recent findings indicate that mitochondrial dysfunction may play a role in the advancement of this diabetic condition. Two RNA transcriptome datasets (codes: GSE185011 and GSE95849), comprising samples from diabetic peripheralneuropathy (DPN) patients and healthy controls (HC), were retrieved from the Gene Expression Omnibus (GEO) database hosted by the National
A real-world multicenter cross-sectional observational study to assess the clinical profile of peripheralneuropathy in patients with diabetes. There are limited studies on the prevalence of diabetic peripheralneuropathy (DPN) and related foot deformities in patients with T2DM from India. To investigate the prevalence, characteristics, and risk factors for foot deformities in Asian-Indian
Acetyl-L-carnitine for the treatment of diabetic peripheralneuropathy. Diabetic peripheralneuropathy (DPN) is a common and severe complication that affects 50% of people with diabetes. Painful DPN is reported to occur in 16% to 24% of people with diabetes. A complete and comprehensive management strategy for the prevention and treatment of DPN, whether painful or not, has not yet been
The accuracy of 10 g monofilament use for clinical screening of diabetes peripheralneuropathy among Indian population. The purpose of this study was to test the diagnostic accuracy of the 10g monofilament to screen for diabetic peripheralneuropathy (DPN) in India. The study further assessed the effect of physical activity, footwear use, and occupation on the outcome. Non-probabilistic
Diagnostic contribution of multi-frequency vibrometry to detection of peripheralneuropathy in type 1 diabetes mellitus compared with nerve conduction studies. The aim was to assess the use of multi-frequency vibrometry (MFV) in detecting diabetic peripheralneuropathy (DPN) in type 1 diabetes in comparison to nerve conduction studies (NCS) and neurothesiometer (NT). Our objectives were
Single-cell transcriptome analysis reveals distinct cell populations in dorsal root ganglia and their potential roles in diabetic peripheralneuropathy. Diabetic peripheralneuropathy (DPN) is a common complication associated with diabetes, and can affect quality of life considerably. Dorsal root ganglion (DRG) plays an important role in the development of DPN. However, the relationship between
The relationship between dietary phosphorus and peripheralneuropathy in the general population of the United States: A preliminary research. Dietary phosphorus intake may serve as a potential predictor for peripheralneuropathy (PN). While past research has predominantly focused on the relationship between dietary phosphorus and bone health, relatively little is known about its role
Study on the Efficacy and Safety of the Huangqi Guizhi Wuwu Decoction in the Prevention and Treatment of Chemotherapy-Induced PeripheralNeuropathy: Meta-Analysis of 32 Randomized Controlled Trials Chemotherapy-induced peripheralneuropathy (CIPN) still lacks efficient therapeutic drugs. This study aimed to systematically evaluate the effects of Huangqi Guizhi Wuwu Decoction (HGWD) alone
Prevalence and factors associated with peripheralneuropathy in a setting of retail pharmacies in Malaysia-A cross-sectional study. Peripheralneuropathy is a common cause for neurological consultation, especially among those with diabetes mellitus. However, research on peripheralneuropathy among the general population is lacking in Malaysia. This study aimed to determine the prevalence and factors associated with peripheralneuropathy in a setting of retail pharmacies. This cross-sectional study of 1283 participants was conducted at retail pharmacies in Selangor. Peripheralneuropathy was defined as the final score in the mild to severe category in the severity rating scale using a biothesiometer. SPSS version 26 was used to perform the analysis. Multiple logistic regressions were used
Pattern, causes and functional outcome of peripheralneuropathies in the Amazon region. Peripheralneuropathies have a wide variety of causes and pathophysiologies. Assuming that there are local particularities in the Amazon region, the aim of this study was to describe the characteristics of patients by determining the factors associated with functional severity. This was a retrospective observational study at Cayenne Hospital between January 2015 and May 2023. We included patients from the French hospital activity monitoring database "Programme de médicalisation des systèmes d'information" by searching for the keywords "neuropathy" "Guillain-Barre syndrome"(GBS) "multineuritis" "polyneuritis". The PeripheralNeuropathy Disability (PND) score was determined to quantify the functional severity
Prevalence of painful diabetic peripheralneuropathy in type 2 diabetes mellitus and diabetic peripheralneuropathy: A nationwide cross-sectional study in mainland China. The study aimed to assess the prevalence and risk factors of painful diabetic peripheralneuropathy (PDPN) in patients with type 2 diabetes mellitus (T2DM) and diabetic peripheralneuropathy (DPN) in mainland China
Acupuncture in diabetic peripheralneuropathy-neurological outcomes of the randomized acupuncture in diabetic peripheralneuropathy trial. Diabetic peripheralneuropathy (DPN) is a common complication of diabetes mellitus and can lead to serious complications. Therapeutic strategies for pain control are available but there are few approaches that influence neurological deficits such as numbness
Effects of CXCR1/2 Blockade with Ladarixin on Streptozotocin-Induced Type 1 Diabetes Mellitus and PeripheralNeuropathy and Retinopathy in Rat. The CXC motif chemokine ligand 8 (CXCL8)-CXC motif chemokine receptor 1/2 (CXCR1/2) axis has been implicated in type 1 diabetes mellitus (T1DM). Its actions on non-immune cells may also contribute to T1DM-associated complications, including painful diabetic peripheralneuropathy (DPN) and diabetic retinopathy (DR). We assessed the efficacy of early (4-8 weeks) or late (8-12 weeks) daily ladarixin (LDX) for the treatment of streptozotocin (STZ)-induced T1DM and the related complications of DPN or DR in male rats. Early LDX mitigated STZ-induced dysmetabolism (i.e., blood glucose, insulin), inflammation in dorsal root ganglion/ sciatic nerve
A Retrospective Cohort Study on the Preliminary Efficacy of Massage Therapy for Chemotherapy-Induced PeripheralNeuropathy Among Cancer Patients. Chemotherapy-induced peripheralneuropathy (CIPN) worsens the quality of life for people with cancer. Massage therapy involves neuromuscular modulations and can potentially reduce CIPN symptoms. We examined the immediate improvements in CIPN-related
A Novel Missense Mutation in SLC12A6 Impairs Ion Transport Function of the Protein to Cause Agenesis of the Corpus Callosum With PeripheralNeuropathy. Agenesis of the corpus callosum with peripheralneuropathy (ACCPN) is a rare autosomal recessive disorder characterized by malformation or absence of the corpus callosum, accompanied by progressive peripheral nerve degeneration. ACCPN