PneumatosisIntestinalis in Children with Intestinal Failure: The Result of Intestinal Stress from Enteral Feeding? The incidence and significance of pneumatosisintestinalis (PI) in children with a diagnosis of intestinal failure is not well understood. The aim of this study was to identify clinical and anatomical factors associated with the imaging findings of PI in patients with intestinal
Multicenter epidemiological survey of pneumatosisintestinalis in Japan. Pneumatosisintestinalis (PI) is a rare condition characterized by gas collection in the intestinal wall. We aimed to determine the etiology and affected segments associated with complications, treatment, and outcome. We conducted a multicenter epidemiological survey using a standardized data collection sheet in Japan
Unrecognized PneumatosisIntestinalis in Antimelanoma Differentiation-Associated Gene 5 Antibody-Associated Dermatomyositis. Pneumatosisintestinalis (PI) is the presence of gas within the bowel wall and may result from several autoimmune diseases, including dermatomyositis (DM). A 55-year-old man with antimelanoma differentiation-associated gene 5 antibody (MDA5)-associated DM and interstitial
Clinical characteristics of pneumoperitoneum with pneumatosisintestinalis detected using computed tomography: A descriptive study. Pneumoperitoneum has always been considered a surgical emergency as it represents a perforation of the gastrointestinal tract. Although several cases of pneumoperitoneum with pneumatosisintestinalis (PI) have been reported, the characteristics of such cases remain
Idiopathic pneumatosisintestinalis secondary to lactulose use in patients with cirrhosis. Few case reports exist that link lactulose use with pneumatosisintestinalis in cirrhotics. This study investigates the relationship between lactulose use and idiopathic pneumatosisintestinalis in a cohort of cirrhotic patients. This case series considers several notable cases of patients with idiopathic pneumatosisintestinalis and concurrent lactulose use. Idiopathic pneumatosisintestinalis was defined as pneumatosisintestinalis with no identifiable etiology. A cohort of 119 patients with cirrhosis and pneumatosisintestinalis were identified in a tertiary care setting, via chart review by a multidisciplinary team. Eleven of these patients were found to have idiopathic pneumatosisintestinalis. Nine
Hepatic portal venous gas with pneumatosisintestinalis secondary to mesenteric ischemia in elderly patients: Two case reports. Hepatic portal venous gas (HPVG) is a rare imaging finding. When HPVG is accompanied with pneumatosisintestinalis (PI), the underlying cause is usually mesenteric ischemia with consequent intestinal necrosis. This combination of clinical conditions is associated
Pneumatosisintestinalis and pneumoretroperitoneum post steroid use in a patient with superior mesenteric artery syndrome. Pneumatosisintestinalis (PI) refers to the presence of gas within the wall of the small or large intestine. PI can be both asymptomatic and life-threatening. The patient was a 50-year-old man with previous cervical spine abscess and osteomyelitis post debridement 4 years ago
Pneumatosisintestinalis and hepatic portal venous gas associated with gas-forming bacterial translocation due to postoperative paralytic ileus: A case report. Pneumatosisintestinalis (PI) and hepatic portal venous gas (HPVG) are rare but potentially lethal conditions in which gas pathologically accumulates in the portal vein and intestinal wall, respectively. Proposed mechanisms include flatus
Occult child abuse presenting as pneumatosisintestinalis and portomesenteric venous gas - a case report. Pneumatosisintestinalis and portomesenteric venous gas are usually caused by necrotizing enterocolitis; however they can occur secondary to abusive abdominal trauma with bone fractures and bruising. It is difficult to recognize initially if there is no bruising on the skin or bone fractures . We report a 1-year-old child with no obvious history of trauma who presented with conscious disturbance. Abdominal computed tomography showed acute ischemic bowel complicated with pneumatosisintestinalis and portomesenteric venous gas. The first impression was septic shock with acute ischemic bowel. Two weeks after admission, brain magnetic resonance imaging showed subdural hemorrhage of different
Pneumatosisintestinalis induced by osimertinib in a patient with lung adenocarcinoma harbouring epidermal growth factor receptor gene mutation with simultaneously detected exon 19 deletion and T790 M point mutation: a case report. Pneumatosisintestinalis is a rare adverse event that occurs in patients with lung cancer, especially those undergoing treatment with epidermal growth factor receptor was started as seventh-line therapy. Follow-up computed tomography on the 97th day after osimertinib administration incidentally demonstrated intra-mural air in the transverse colon, as well as intrahepatic portal vein gas. Pneumatosisintestinalis and portal vein gas improved by fasting and temporary interruption of osimertinib. Osimertinib was then restarted and continued without recurrence of pneumatosis
Gefitinib successfully administered in a lung cancer patient with leptomeningeal carcinomatosis after erlotinib-induced pneumatosisintestinalis. Pneumatosisintestinalis (PI) is a rare complication of chemotherapy, characterized by multiple gas accumulations within the bowel wall. A 71-year-old woman with epidermal growth factor receptor (EGFR) mutation-positive lung adenocarcinoma was admitted
Pneumatosisintestinalis after lung transplantation for pulmonary graft-versus-host disease Pneumatosisintestinalis, which could complicate a spectrum of clinical conditions ranging from benign to life-threatening, is a rarely encountered complication after lung transplantation (LT). We describe two cases in which PI developed as a complication following LT for pulmonary graft-versus-host
Pneumatosisintestinalis a trap for the unwary: Case series and literature review PneumatosisIntestinalis (PI) can present with a broad range of presentations from chronic and non-specific to acute and life threatening. It is paradoxically one of the few conditions where a pneumoperitoneum found in the diagnostic workup is not necessarily an indication for laparotomy. The first case is of a 75
When the Benign PneumatosisIntestinalis Becomes No Longer Benign: A Rare Case of Bowel Perforation in a Patient with Systemic Sclerosis Systemic sclerosis is a multisystem disease featured with autoimmunity and organ fibrosis. Although gastrointestinal (GI) tract involvement is common in patients with systemic sclerosis, colonic perforation is extremely rare. Benign pneumatosisintestinalis , a phenomenon more frequently seen in rheumatologic conditions, makes the diagnosis of colonic perforation even more challenging. We report a unique case of colonic perforation in a patient with chronic systemic sclerosis. This patient initially presented with mild abdominal pain and hematemesis. Urgent upper endoscopy was unremarkable and radiology showed stable pneumatosisintestinalis. Due to worsening
Survival from a 75% TBSA thermal injury complicated by bowel ischemia presenting with pneumatosisintestinalis Thermal injury is associated with an increased risk of abdominal complications such as ischemia, infarction and pneumatosisintestinalis (PI). PI is characterized by gas in the intestinal wall and, when diagnosed it can signify the presence of a life-threatening condition. We present
Pseudolipomatosis of the Colon and Cecum Followed by PneumatosisIntestinalis A 74-year-old Japanese woman was diagnosed with pseudolipomatosis of the cecum and ascending colon. Colonoscopy was performed, which revealed the presence of slightly elevated white lesions, while a magnifying observation showed microbubbles within the mucosa. A month after colonoscopy, the patient was diagnosed with pneumatosisintestinalis. Although the exact pathogenesis is unclear, pneumatosisintestinalis may arise secondary to pseudolipomatosis. This case also indicates that a magnifying observation during colonoscopy may aid in the diagnosis of pseudolipomatosis of the large intestine, since it shows microbubbles within the mucosa, which may be a distinctive feature reflecting the pathology of this disease.
Digital gangrene and pneumatosisintestinalis associated with calciphylaxis Reports of calciphylaxis or calcific uremic arteriolopathy associated with acral and gastrointestinal involvement are rare. We describe a 36-year-old white woman with end-stage renal disease on hemodialysis after failed kidney and pancreas transplantation who developed dry gangrene of bilateral digits, osteomyelitis , and small bowel ischemia within several months of each presentation. She had multiple débridements of a septic right ankle. Computed tomography angiography showed severe vascular calcification and pneumatosisintestinalis. She underwent intestinal resection for gangrenous small bowel. A multidisciplinary approach with aggressive medical and surgical management may improve survival. Our case
A case of recurrent pneumatosisintestinalisPneumatosisintestinalis (PI), defined as free gas in the bowel wall, is associated with autoimmune conditions, drugs, pulmonary disease and many other etiologies. Patients with findings of PI may have variable clinical presentations, ranging from asymptomatic to acute abdomen necessitating urgent surgery. Here, we present the case of an individual
Pneumatosisintestinalis in solid organ transplant recipients Pneumatosisintestinalis (PI) is an uncommon medical condition in which gas pockets form in the walls of the gastrointestinal tract. The mechanism by which this occurs is poorly understood; however, it is often seen as a sign of serious bowel ischemia, which is a surgical emergency. Since the early days of solid organ transplantation